ZAPB_SALDC
ID ZAPB_SALDC Reviewed; 79 AA.
AC B5FPT6;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 14-OCT-2008, sequence version 1.
DT 25-MAY-2022, entry version 69.
DE RecName: Full=Cell division protein ZapB {ECO:0000255|HAMAP-Rule:MF_01196};
GN Name=zapB {ECO:0000255|HAMAP-Rule:MF_01196}; OrderedLocusNames=SeD_A4487;
OS Salmonella dublin (strain CT_02021853).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=439851;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CT_02021853;
RX PubMed=21602358; DOI=10.1128/jb.00297-11;
RA Fricke W.F., Mammel M.K., McDermott P.F., Tartera C., White D.G.,
RA Leclerc J.E., Ravel J., Cebula T.A.;
RT "Comparative genomics of 28 Salmonella enterica isolates: evidence for
RT CRISPR-mediated adaptive sublineage evolution.";
RL J. Bacteriol. 193:3556-3568(2011).
CC -!- FUNCTION: Non-essential, abundant cell division factor that is required
CC for proper Z-ring formation. It is recruited early to the divisome by
CC direct interaction with FtsZ, stimulating Z-ring assembly and thereby
CC promoting cell division earlier in the cell cycle. Its recruitment to
CC the Z-ring requires functional FtsA or ZipA. {ECO:0000255|HAMAP-
CC Rule:MF_01196}.
CC -!- SUBUNIT: Homodimer. The ends of the coiled-coil dimer bind to each
CC other, forming polymers. Interacts with FtsZ. {ECO:0000255|HAMAP-
CC Rule:MF_01196}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01196}.
CC Note=Localizes to the septum at mid-cell, in a FtsZ-like pattern.
CC {ECO:0000255|HAMAP-Rule:MF_01196}.
CC -!- SIMILARITY: Belongs to the ZapB family. {ECO:0000255|HAMAP-
CC Rule:MF_01196}.
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DR EMBL; CP001144; ACH74157.1; -; Genomic_DNA.
DR RefSeq; WP_000051370.1; NC_011205.1.
DR AlphaFoldDB; B5FPT6; -.
DR SMR; B5FPT6; -.
DR KEGG; sed:SeD_A4487; -.
DR HOGENOM; CLU_171174_2_0_6; -.
DR OMA; VQSAQHG; -.
DR Proteomes; UP000008322; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01196; ZapB; 1.
DR InterPro; IPR009252; Cell_div_ZapB.
DR Pfam; PF06005; ZapB; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Coiled coil; Cytoplasm; Septation.
FT CHAIN 1..79
FT /note="Cell division protein ZapB"
FT /id="PRO_1000138444"
FT REGION 36..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 3..79
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01196"
SQ SEQUENCE 79 AA; 9312 MW; AAC86A5B410EFFAA CRC64;
MSLEVFEKLE AKVQQAIDTI TLLQMEIEEL KEKNNSLTQE VQSAQHQREE LERENNSLKE
QQSGWQERLQ ALLGRMEEV