CC138_MOUSE
ID CC138_MOUSE Reviewed; 680 AA.
AC Q0VF22; Q8CG93;
DT 29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-SEP-2006, sequence version 1.
DT 03-AUG-2022, entry version 87.
DE RecName: Full=Coiled-coil domain-containing protein 138;
GN Name=Ccdc138;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=FVB/N; TISSUE=Brain, and Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [2]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-64, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
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DR EMBL; BC042726; AAH42726.1; -; mRNA.
DR EMBL; BC119028; AAI19029.1; -; mRNA.
DR EMBL; BC119030; AAI19031.1; -; mRNA.
DR CCDS; CCDS48565.1; -.
DR RefSeq; NP_001156428.1; NM_001162956.1.
DR AlphaFoldDB; Q0VF22; -.
DR SMR; Q0VF22; -.
DR BioGRID; 217987; 1.
DR STRING; 10090.ENSMUSP00000043040; -.
DR iPTMnet; Q0VF22; -.
DR PhosphoSitePlus; Q0VF22; -.
DR MaxQB; Q0VF22; -.
DR PaxDb; Q0VF22; -.
DR PRIDE; Q0VF22; -.
DR ProteomicsDB; 283707; -.
DR Antibodypedia; 33133; 69 antibodies from 15 providers.
DR Ensembl; ENSMUST00000036576; ENSMUSP00000043040; ENSMUSG00000038010.
DR GeneID; 76138; -.
DR KEGG; mmu:76138; -.
DR UCSC; uc007fdf.2; mouse.
DR CTD; 165055; -.
DR MGI; MGI:1923388; Ccdc138.
DR VEuPathDB; HostDB:ENSMUSG00000038010; -.
DR eggNOG; ENOG502QU8J; Eukaryota.
DR GeneTree; ENSGT00390000000217; -.
DR HOGENOM; CLU_026862_0_0_1; -.
DR InParanoid; Q0VF22; -.
DR OMA; KHLNVNC; -.
DR OrthoDB; 852769at2759; -.
DR PhylomeDB; Q0VF22; -.
DR TreeFam; TF329029; -.
DR BioGRID-ORCS; 76138; 0 hits in 74 CRISPR screens.
DR ChiTaRS; Ccdc138; mouse.
DR PRO; PR:Q0VF22; -.
DR Proteomes; UP000000589; Chromosome 10.
DR RNAct; Q0VF22; protein.
DR Bgee; ENSMUSG00000038010; Expressed in spermatid and 78 other tissues.
DR InterPro; IPR038798; CCDC138.
DR PANTHER; PTHR34523; PTHR34523; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Phosphoprotein; Reference proteome.
FT CHAIN 1..680
FT /note="Coiled-coil domain-containing protein 138"
FT /id="PRO_0000288456"
FT REGION 390..410
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 260..339
FT /evidence="ECO:0000255"
FT MOD_RES 63
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q96M89"
FT MOD_RES 64
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:21183079"
FT MOD_RES 484
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q96M89"
SQ SEQUENCE 680 AA; 77947 MW; 84ED06340C051385 CRC64;
MERRVVKPPG QDMVVERLKS RYGLAGRCPV EENDMTGVWA ALMNQQHELS DFDQTKYKRR
IVTSPDGLDT YSSGDKVGSS PRYYSDGRNH PTPPFCSSFK HLNVNCLDDE LDSFHDLKKW
ETEKELMEDD HRDGASKITK QSFKEMETDA LMTSMASGLE TECCSGSIDS PLKQAVYPRP
KVSKKQGLLP HEINQIYDEL YHIHMKLQYE TTAQKKFAEE LQKREQFLAE REQLLFSHET
ALSKIKGVKE EVLTRFQILK EQHGTEIEHL TEALKEKNKE NKRMRSSFDT LRELNDNLRK
QLNEVSEENK KMEIQAKRVQ ARLDNLQRKY EFMTVQRLKG DSHAAHEVKS SKQEKAPAPK
PFKAALNGQV YELLTVFMDW ISDCHLSKVE PEEPGVDGGK PPAKPSQRSD IQEKCVKLLP
MMTEQLQWMP LVSAKLHEPF VRFIYWSLRQ LDASARQSTM ASTLRRLGED VFKGVTMKGT
QDNSLEHSVE NKAKTAVFFK SSSLPLRFLS TLIVLRTVTQ ADYLAQAFDS LCLDLKTDEG
KTLFLEYQAI PVILKHLRIS SKGLLSNVID SLLQMTVESK SLQPFLEACS NSLFFRTCSV
LLRTPKLDLH ILEKLSIILQ KLSKIKSNKK LFEVFTIHLM LQEIQRTTHP EHAFLCINLN
STLFNLGLTK CNSLVTSTSH