ZAPD_ECO27
ID ZAPD_ECO27 Reviewed; 247 AA.
AC B7UIF1;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 1.
DT 25-MAY-2022, entry version 68.
DE RecName: Full=Cell division protein ZapD {ECO:0000255|HAMAP-Rule:MF_01092};
DE AltName: Full=Z ring-associated protein D {ECO:0000255|HAMAP-Rule:MF_01092};
GN Name=zapD {ECO:0000255|HAMAP-Rule:MF_01092}; OrderedLocusNames=E2348C_0106;
OS Escherichia coli O127:H6 (strain E2348/69 / EPEC).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=574521;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E2348/69 / EPEC;
RX PubMed=18952797; DOI=10.1128/jb.01238-08;
RA Iguchi A., Thomson N.R., Ogura Y., Saunders D., Ooka T., Henderson I.R.,
RA Harris D., Asadulghani M., Kurokawa K., Dean P., Kenny B., Quail M.A.,
RA Thurston S., Dougan G., Hayashi T., Parkhill J., Frankel G.;
RT "Complete genome sequence and comparative genome analysis of
RT enteropathogenic Escherichia coli O127:H6 strain E2348/69.";
RL J. Bacteriol. 191:347-354(2009).
CC -!- FUNCTION: Cell division factor that enhances FtsZ-ring assembly.
CC Directly interacts with FtsZ and promotes bundling of FtsZ
CC protofilaments, with a reduction in FtsZ GTPase activity.
CC {ECO:0000255|HAMAP-Rule:MF_01092}.
CC -!- SUBUNIT: Interacts with FtsZ. {ECO:0000255|HAMAP-Rule:MF_01092}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01092}.
CC Note=Localizes to mid-cell in an FtsZ-dependent manner.
CC {ECO:0000255|HAMAP-Rule:MF_01092}.
CC -!- SIMILARITY: Belongs to the ZapD family. {ECO:0000255|HAMAP-
CC Rule:MF_01092}.
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DR EMBL; FM180568; CAS07654.1; -; Genomic_DNA.
DR RefSeq; WP_001194731.1; NC_011601.1.
DR AlphaFoldDB; B7UIF1; -.
DR SMR; B7UIF1; -.
DR EnsemblBacteria; CAS07654; CAS07654; E2348C_0106.
DR KEGG; ecg:E2348C_0106; -.
DR HOGENOM; CLU_076303_0_0_6; -.
DR OMA; LPAYYAW; -.
DR Proteomes; UP000008205; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR Gene3D; 2.60.440.10; -; 1.
DR HAMAP; MF_01092; ZapD; 1.
DR InterPro; IPR009777; ZapD.
DR InterPro; IPR027462; ZapD_C.
DR InterPro; IPR036268; ZapD_sf.
DR PANTHER; PTHR39455; PTHR39455; 1.
DR Pfam; PF07072; ZapD; 1.
DR SUPFAM; SSF160950; SSF160950; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Cytoplasm; Septation.
FT CHAIN 1..247
FT /note="Cell division protein ZapD"
FT /id="PRO_1000149888"
SQ SEQUENCE 247 AA; 28278 MW; 390BC17A7FA844AC CRC64;
MQTQVLFEHP LNEKMRTWLR IEFLIQQLTV NLPIVDHAGA LHFFRNVSEL LDVFERGEVR
TELLKELDRQ QRKLQTWIGV PGVDQSRIEA LIQQLKAAGS VLISAPRIGQ FLREDRLIAL
VRQRLSIPGG CCSFDLPTLH IWLHLPQAQR DSQVETWIAS LNPLTQALTM VLDLIRQSAP
FRKQTSLNGF YQDNGGDADL LRLNLSLDSQ LYPQISGHKS RFAIRFMPLD SENGQVPERL
DFELACC