ZAPD_ECO55
ID ZAPD_ECO55 Reviewed; 247 AA.
AC B7LFX0;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 1.
DT 25-MAY-2022, entry version 61.
DE RecName: Full=Cell division protein ZapD {ECO:0000255|HAMAP-Rule:MF_01092};
DE AltName: Full=Z ring-associated protein D {ECO:0000255|HAMAP-Rule:MF_01092};
GN Name=zapD {ECO:0000255|HAMAP-Rule:MF_01092};
GN OrderedLocusNames=EC55989_0096;
OS Escherichia coli (strain 55989 / EAEC).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=585055;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=55989 / EAEC;
RX PubMed=19165319; DOI=10.1371/journal.pgen.1000344;
RA Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P.,
RA Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H.,
RA Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E.,
RA Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C.,
RA Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S.,
RA Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J.,
RA Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E.;
RT "Organised genome dynamics in the Escherichia coli species results in
RT highly diverse adaptive paths.";
RL PLoS Genet. 5:E1000344-E1000344(2009).
CC -!- FUNCTION: Cell division factor that enhances FtsZ-ring assembly.
CC Directly interacts with FtsZ and promotes bundling of FtsZ
CC protofilaments, with a reduction in FtsZ GTPase activity.
CC {ECO:0000255|HAMAP-Rule:MF_01092}.
CC -!- SUBUNIT: Interacts with FtsZ. {ECO:0000255|HAMAP-Rule:MF_01092}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01092}.
CC Note=Localizes to mid-cell in an FtsZ-dependent manner.
CC {ECO:0000255|HAMAP-Rule:MF_01092}.
CC -!- SIMILARITY: Belongs to the ZapD family. {ECO:0000255|HAMAP-
CC Rule:MF_01092}.
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DR EMBL; CU928145; CAU95984.1; -; Genomic_DNA.
DR RefSeq; WP_001194734.1; NC_011748.1.
DR AlphaFoldDB; B7LFX0; -.
DR SMR; B7LFX0; -.
DR EnsemblBacteria; CAU95984; CAU95984; EC55989_0096.
DR GeneID; 66671609; -.
DR KEGG; eck:EC55989_0096; -.
DR HOGENOM; CLU_076303_0_0_6; -.
DR OMA; LPAYYAW; -.
DR Proteomes; UP000000746; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR Gene3D; 2.60.440.10; -; 1.
DR HAMAP; MF_01092; ZapD; 1.
DR InterPro; IPR009777; ZapD.
DR InterPro; IPR027462; ZapD_C.
DR InterPro; IPR036268; ZapD_sf.
DR PANTHER; PTHR39455; PTHR39455; 1.
DR Pfam; PF07072; ZapD; 1.
DR SUPFAM; SSF160950; SSF160950; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Cytoplasm; Septation.
FT CHAIN 1..247
FT /note="Cell division protein ZapD"
FT /id="PRO_1000149889"
SQ SEQUENCE 247 AA; 28292 MW; 3C0B917A7FA844AC CRC64;
MQTQVLFEHP LNEKMRTWLR IEFLIQQLTV NLPIVDHAGA LHFFRNVSEL LDVFERGEVR
TELLKELDRQ QRKLQTWIGV PGVDQSRIEA LIQQLKAAGS VLISAPRIGQ FLREDRLIAL
VRQRLSIPGG CCSFDLPTLH IWLHLPQAQR DSQVETWIAS LNPLTQALTM VLDLIRQSAP
FRKQTSLNGF YQDNGGDADL LRLNLSLDSQ LYPQISGHKS RFAIRFMPLD TENGQVPERL
DFELACC