ZAPD_SALTY
ID ZAPD_SALTY Reviewed; 247 AA.
AC P67693; Q8XEX8;
DT 11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 83.
DE RecName: Full=Cell division protein ZapD {ECO:0000255|HAMAP-Rule:MF_01092};
DE AltName: Full=Z ring-associated protein D {ECO:0000255|HAMAP-Rule:MF_01092};
GN Name=zapD {ECO:0000255|HAMAP-Rule:MF_01092}; OrderedLocusNames=STM0139;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- FUNCTION: Cell division factor that enhances FtsZ-ring assembly.
CC Directly interacts with FtsZ and promotes bundling of FtsZ
CC protofilaments, with a reduction in FtsZ GTPase activity.
CC {ECO:0000255|HAMAP-Rule:MF_01092}.
CC -!- SUBUNIT: Interacts with FtsZ. {ECO:0000255|HAMAP-Rule:MF_01092}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01092}.
CC Note=Localizes to mid-cell in an FtsZ-dependent manner.
CC {ECO:0000255|HAMAP-Rule:MF_01092}.
CC -!- SIMILARITY: Belongs to the ZapD family. {ECO:0000255|HAMAP-
CC Rule:MF_01092}.
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DR EMBL; AE006468; AAL19103.1; -; Genomic_DNA.
DR RefSeq; NP_459144.1; NC_003197.2.
DR RefSeq; WP_000557441.1; NC_003197.2.
DR PDB; 5GNP; X-ray; 2.80 A; A=3-247.
DR PDBsum; 5GNP; -.
DR AlphaFoldDB; P67693; -.
DR SMR; P67693; -.
DR STRING; 99287.STM0139; -.
DR PaxDb; P67693; -.
DR EnsemblBacteria; AAL19103; AAL19103; STM0139.
DR GeneID; 1251657; -.
DR KEGG; stm:STM0139; -.
DR PATRIC; fig|99287.12.peg.147; -.
DR HOGENOM; CLU_076303_0_0_6; -.
DR OMA; LPAYYAW; -.
DR PhylomeDB; P67693; -.
DR BioCyc; SENT99287:STM0139-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0032153; C:cell division site; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR GO; GO:0043093; P:FtsZ-dependent cytokinesis; IBA:GO_Central.
DR Gene3D; 2.60.440.10; -; 1.
DR HAMAP; MF_01092; ZapD; 1.
DR InterPro; IPR009777; ZapD.
DR InterPro; IPR027462; ZapD_C.
DR InterPro; IPR036268; ZapD_sf.
DR PANTHER; PTHR39455; PTHR39455; 1.
DR Pfam; PF07072; ZapD; 1.
DR SUPFAM; SSF160950; SSF160950; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cell cycle; Cell division; Cytoplasm; Reference proteome;
KW Septation.
FT CHAIN 1..247
FT /note="Cell division protein ZapD"
FT /id="PRO_0000211678"
FT STRAND 4..12
FT /evidence="ECO:0007829|PDB:5GNP"
FT HELIX 13..30
FT /evidence="ECO:0007829|PDB:5GNP"
FT HELIX 37..53
FT /evidence="ECO:0007829|PDB:5GNP"
FT HELIX 54..56
FT /evidence="ECO:0007829|PDB:5GNP"
FT HELIX 59..74
FT /evidence="ECO:0007829|PDB:5GNP"
FT STRAND 77..79
FT /evidence="ECO:0007829|PDB:5GNP"
FT HELIX 85..104
FT /evidence="ECO:0007829|PDB:5GNP"
FT HELIX 110..114
FT /evidence="ECO:0007829|PDB:5GNP"
FT HELIX 116..124
FT /evidence="ECO:0007829|PDB:5GNP"
FT TURN 133..135
FT /evidence="ECO:0007829|PDB:5GNP"
FT HELIX 137..142
FT /evidence="ECO:0007829|PDB:5GNP"
FT HELIX 147..159
FT /evidence="ECO:0007829|PDB:5GNP"
FT HELIX 162..176
FT /evidence="ECO:0007829|PDB:5GNP"
FT STRAND 182..187
FT /evidence="ECO:0007829|PDB:5GNP"
FT STRAND 190..194
FT /evidence="ECO:0007829|PDB:5GNP"
FT STRAND 199..206
FT /evidence="ECO:0007829|PDB:5GNP"
FT HELIX 207..209
FT /evidence="ECO:0007829|PDB:5GNP"
FT STRAND 211..230
FT /evidence="ECO:0007829|PDB:5GNP"
FT TURN 231..233
FT /evidence="ECO:0007829|PDB:5GNP"
FT STRAND 238..246
FT /evidence="ECO:0007829|PDB:5GNP"
SQ SEQUENCE 247 AA; 28426 MW; E1B9826AD004BE48 CRC64;
MHTQVLFEHP LNEKMRTWLR IEFLIQQLSI NLPIADHAGA LHFFRNISDL LDVFERGEVR
TELLKELERQ QRKLQAWVEV PGVDQDRIEA LRQQLKSAGS VLISAPRIGQ QLREDRLIAL
VRQRLSIPGG CCSFDLPTLH IWLHLQQAQR DAQIESWLAS LNPLTQALTL VLDLIRNSAP
FRKQTSLNGF YQDNGDDADL LRLMLTLDSQ LYPQISGHKS RFAIRFMPLD SENGLVPERL
DFELACC
