ID   ZAPD_VIBC3              Reviewed;         246 AA.
AC   A5F5K1; C3M4R9;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Cell division protein ZapD {ECO:0000255|HAMAP-Rule:MF_01092};
DE   AltName: Full=Z ring-associated protein D {ECO:0000255|HAMAP-Rule:MF_01092};
GN   Name=zapD {ECO:0000255|HAMAP-Rule:MF_01092};
GN   OrderedLocusNames=VC0395_A2005, VC395_2543;
OS   Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 /
OS   O395).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=345073;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39541 / Classical Ogawa 395 / O395;
RA   Heidelberg J.;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39541 / Classical Ogawa 395 / O395;
RX   PubMed=19115014; DOI=10.1371/journal.pone.0004053;
RA   Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J.,
RA   Wang W., Wang J., Qian W., Li D., Wang L.;
RT   "A recalibrated molecular clock and independent origins for the cholera
RT   pandemic clones.";
RL   PLoS ONE 3:E4053-E4053(2008).
CC   -!- FUNCTION: Cell division factor that enhances FtsZ-ring assembly.
CC       Directly interacts with FtsZ and promotes bundling of FtsZ
CC       protofilaments, with a reduction in FtsZ GTPase activity.
CC       {ECO:0000255|HAMAP-Rule:MF_01092}.
CC   -!- SUBUNIT: Interacts with FtsZ. {ECO:0000255|HAMAP-Rule:MF_01092}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01092}.
CC       Note=Localizes to mid-cell in an FtsZ-dependent manner.
CC       {ECO:0000255|HAMAP-Rule:MF_01092}.
CC   -!- SIMILARITY: Belongs to the ZapD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01092}.
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DR   EMBL; CP000627; ABQ21319.1; -; Genomic_DNA.
DR   EMBL; CP001235; ACP10530.1; -; Genomic_DNA.
DR   RefSeq; WP_000207198.1; NZ_JAACZH010000010.1.
DR   AlphaFoldDB; A5F5K1; -.
DR   SMR; A5F5K1; -.
DR   STRING; 345073.VC395_2543; -.
DR   EnsemblBacteria; ABQ21319; ABQ21319; VC0395_A2005.
DR   GeneID; 57741034; -.
DR   KEGG; vco:VC0395_A2005; -.
DR   KEGG; vcr:VC395_2543; -.
DR   PATRIC; fig|345073.21.peg.2445; -.
DR   eggNOG; COG4582; Bacteria.
DR   HOGENOM; CLU_076303_0_0_6; -.
DR   OMA; LPAYYAW; -.
DR   Proteomes; UP000000249; Chromosome 2.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR   GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.60.440.10; -; 1.
DR   HAMAP; MF_01092; ZapD; 1.
DR   InterPro; IPR009777; ZapD.
DR   InterPro; IPR027462; ZapD_C.
DR   InterPro; IPR036268; ZapD_sf.
DR   PANTHER; PTHR39455; PTHR39455; 1.
DR   Pfam; PF07072; ZapD; 1.
DR   SUPFAM; SSF160950; SSF160950; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cytoplasm; Septation.
FT   CHAIN           1..246
FT                   /note="Cell division protein ZapD"
FT                   /id="PRO_1000073027"
SQ   SEQUENCE   246 AA;  28841 MW;  0E208D249FB3927C CRC64;
     MTTHQFEHPL NEKTRIYLRV EALLNQMERA STFSDGIQHQ LFFRSLFDML EIFEQIQLKS
     ELAKDMEKQR LTYRSWLHVE GVDQEMLNSL LTEVDEVHRD LMSAERFGQS LKEDRFLSAI
     RQRFNLPGGS CCFDLPALHY WLHLPLDRKM RDAQQWMQTV TPLSNALKLW LKLTRETGHY
     RSRMASNGFY QSDAEDANIL RLAIPLEYGV YPMISGHKNR FAIKFIDFHS GQACTQDIAF
     DLAVCC