ID   ZAPD_VIBCH              Reviewed;         246 AA.
AC   Q9KPE2;
DT   14-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Cell division protein ZapD {ECO:0000255|HAMAP-Rule:MF_01092};
DE   AltName: Full=Z ring-associated protein D {ECO:0000255|HAMAP-Rule:MF_01092};
GN   Name=zapD {ECO:0000255|HAMAP-Rule:MF_01092}; OrderedLocusNames=VC_2428;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   -!- FUNCTION: Cell division factor that enhances FtsZ-ring assembly.
CC       Directly interacts with FtsZ and promotes bundling of FtsZ
CC       protofilaments, with a reduction in FtsZ GTPase activity.
CC       {ECO:0000255|HAMAP-Rule:MF_01092}.
CC   -!- SUBUNIT: Interacts with FtsZ. {ECO:0000255|HAMAP-Rule:MF_01092}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01092}.
CC       Note=Localizes to mid-cell in an FtsZ-dependent manner.
CC       {ECO:0000255|HAMAP-Rule:MF_01092}.
CC   -!- SIMILARITY: Belongs to the ZapD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01092}.
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DR   EMBL; AE003852; AAF95571.1; -; Genomic_DNA.
DR   PIR; D82078; D82078.
DR   RefSeq; NP_232058.1; NC_002505.1.
DR   RefSeq; WP_000207198.1; NZ_LT906614.1.
DR   AlphaFoldDB; Q9KPE2; -.
DR   SMR; Q9KPE2; -.
DR   STRING; 243277.VC_2428; -.
DR   DNASU; 2612970; -.
DR   EnsemblBacteria; AAF95571; AAF95571; VC_2428.
DR   GeneID; 57741034; -.
DR   KEGG; vch:VC_2428; -.
DR   PATRIC; fig|243277.26.peg.2311; -.
DR   eggNOG; COG4582; Bacteria.
DR   HOGENOM; CLU_076303_0_0_6; -.
DR   OMA; LPAYYAW; -.
DR   BioCyc; VCHO:VC2428-MON; -.
DR   Proteomes; UP000000584; Chromosome 1.
DR   GO; GO:0032153; C:cell division site; IBA:GO_Central.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR   GO; GO:0043093; P:FtsZ-dependent cytokinesis; IBA:GO_Central.
DR   Gene3D; 2.60.440.10; -; 1.
DR   HAMAP; MF_01092; ZapD; 1.
DR   InterPro; IPR009777; ZapD.
DR   InterPro; IPR027462; ZapD_C.
DR   InterPro; IPR036268; ZapD_sf.
DR   PANTHER; PTHR39455; PTHR39455; 1.
DR   Pfam; PF07072; ZapD; 1.
DR   SUPFAM; SSF160950; SSF160950; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cytoplasm; Reference proteome; Septation.
FT   CHAIN           1..246
FT                   /note="Cell division protein ZapD"
FT                   /id="PRO_0000211682"
SQ   SEQUENCE   246 AA;  28841 MW;  0E208D249FB3927C CRC64;
     MTTHQFEHPL NEKTRIYLRV EALLNQMERA STFSDGIQHQ LFFRSLFDML EIFEQIQLKS
     ELAKDMEKQR LTYRSWLHVE GVDQEMLNSL LTEVDEVHRD LMSAERFGQS LKEDRFLSAI
     RQRFNLPGGS CCFDLPALHY WLHLPLDRKM RDAQQWMQTV TPLSNALKLW LKLTRETGHY
     RSRMASNGFY QSDAEDANIL RLAIPLEYGV YPMISGHKNR FAIKFIDFHS GQACTQDIAF
     DLAVCC