ID   ZAPD_VIBCM              Reviewed;         246 AA.
AC   C3LQX1;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2009, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=Cell division protein ZapD {ECO:0000255|HAMAP-Rule:MF_01092};
DE   AltName: Full=Z ring-associated protein D {ECO:0000255|HAMAP-Rule:MF_01092};
GN   Name=zapD {ECO:0000255|HAMAP-Rule:MF_01092}; OrderedLocusNames=VCM66_2351;
OS   Vibrio cholerae serotype O1 (strain M66-2).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=579112;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M66-2;
RX   PubMed=19115014; DOI=10.1371/journal.pone.0004053;
RA   Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J.,
RA   Wang W., Wang J., Qian W., Li D., Wang L.;
RT   "A recalibrated molecular clock and independent origins for the cholera
RT   pandemic clones.";
RL   PLoS ONE 3:E4053-E4053(2008).
CC   -!- FUNCTION: Cell division factor that enhances FtsZ-ring assembly.
CC       Directly interacts with FtsZ and promotes bundling of FtsZ
CC       protofilaments, with a reduction in FtsZ GTPase activity.
CC       {ECO:0000255|HAMAP-Rule:MF_01092}.
CC   -!- SUBUNIT: Interacts with FtsZ. {ECO:0000255|HAMAP-Rule:MF_01092}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01092}.
CC       Note=Localizes to mid-cell in an FtsZ-dependent manner.
CC       {ECO:0000255|HAMAP-Rule:MF_01092}.
CC   -!- SIMILARITY: Belongs to the ZapD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01092}.
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DR   EMBL; CP001233; ACP06649.1; -; Genomic_DNA.
DR   RefSeq; WP_000207198.1; NC_012578.1.
DR   AlphaFoldDB; C3LQX1; -.
DR   SMR; C3LQX1; -.
DR   EnsemblBacteria; ACP06649; ACP06649; VCM66_2351.
DR   GeneID; 57741034; -.
DR   KEGG; vcm:VCM66_2351; -.
DR   HOGENOM; CLU_076303_0_0_6; -.
DR   OMA; LPAYYAW; -.
DR   Proteomes; UP000001217; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR   GO; GO:0043093; P:FtsZ-dependent cytokinesis; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.60.440.10; -; 1.
DR   HAMAP; MF_01092; ZapD; 1.
DR   InterPro; IPR009777; ZapD.
DR   InterPro; IPR027462; ZapD_C.
DR   InterPro; IPR036268; ZapD_sf.
DR   PANTHER; PTHR39455; PTHR39455; 1.
DR   Pfam; PF07072; ZapD; 1.
DR   SUPFAM; SSF160950; SSF160950; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cytoplasm; Septation.
FT   CHAIN           1..246
FT                   /note="Cell division protein ZapD"
FT                   /id="PRO_1000149892"
SQ   SEQUENCE   246 AA;  28841 MW;  0E208D249FB3927C CRC64;
     MTTHQFEHPL NEKTRIYLRV EALLNQMERA STFSDGIQHQ LFFRSLFDML EIFEQIQLKS
     ELAKDMEKQR LTYRSWLHVE GVDQEMLNSL LTEVDEVHRD LMSAERFGQS LKEDRFLSAI
     RQRFNLPGGS CCFDLPALHY WLHLPLDRKM RDAQQWMQTV TPLSNALKLW LKLTRETGHY
     RSRMASNGFY QSDAEDANIL RLAIPLEYGV YPMISGHKNR FAIKFIDFHS GQACTQDIAF
     DLAVCC