ID   ZAR1_TAKRU              Reviewed;         320 AA.
AC   Q7T3T9;
DT   15-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=Zygote arrest protein 1;
DE   AltName: Full=Oocyte-specific maternal effect factor;
GN   Name=zar1;
OS   Takifugu rubripes (Japanese pufferfish) (Fugu rubripes).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Tetradontoidea; Tetraodontidae; Takifugu.
OX   NCBI_TaxID=31033;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=12773403; DOI=10.1095/biolreprod.103.016022;
RA   Wu X., Wang P., Brown C.A., Zilinski C.A., Matzuk M.M.;
RT   "Zygote arrest 1 (Zar1) is an evolutionarily conserved gene expressed in
RT   vertebrate ovaries.";
RL   Biol. Reprod. 69:861-867(2003).
CC   -!- FUNCTION: Essential for female fertility. May play a role in the
CC       oocyte-to-embryo transition (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ZAR1 family. {ECO:0000305}.
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DR   EMBL; AY283177; AAP37039.1; -; mRNA.
DR   RefSeq; NP_001027939.1; NM_001032767.1.
DR   AlphaFoldDB; Q7T3T9; -.
DR   GeneID; 446008; -.
DR   KEGG; tru:446008; -.
DR   CTD; 326340; -.
DR   InParanoid; Q7T3T9; -.
DR   OrthoDB; 822936at2759; -.
DR   Proteomes; UP000005226; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR026775; Zar1.
DR   InterPro; IPR027377; Znf-3CxxC.
DR   PANTHER; PTHR31054; PTHR31054; 1.
DR   Pfam; PF13695; zf-3CxxC; 1.
DR   SMART; SM01328; zf-3CxxC; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Developmental protein; Reference proteome.
FT   CHAIN           1..320
FT                   /note="Zygote arrest protein 1"
FT                   /id="PRO_0000187015"
FT   REGION          106..130
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          155..208
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        177..202
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   320 AA;  36796 MW;  885957EE9B5B2706 CRC64;
     MATYCDEPVD SYFYSSYNPY MGRYPRHRDA GWKYKSYLSH YGDTSEAFSN QQRAQLKSIL
     SQINPKLTPR LRKANTKDVA VQVNPKRDAS VQCSIGPRTL LVVKRELRRR RKLNPGPPGT
     PQKTEGEVRY PRTLAVYSPI AFRSVTSFLV ETGKDRPAAE AQAEELPGEQ PEQKGGENQA
     GEETNANLPE QRKPQSEDAQ TAADAEGSKG KARVRFQFLE QKYGYYHCRE CNLRWESAYV
     WCVQGTNKVY FKQFCRKCQK DFNPYRVEDI TCHVCNKARC ACAETQRHVD PKRPHRQDLC
     GRCKGKRLSC DSTFSFKYIV