ZAT10_ARATH
ID ZAT10_ARATH Reviewed; 227 AA.
AC Q96289; Q42423; Q9SFY6;
DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 03-AUG-2022, entry version 153.
DE RecName: Full=Zinc finger protein ZAT10;
DE AltName: Full=Salt-tolerance zinc finger;
GN Name=ZAT10; Synonyms=STZ; OrderedLocusNames=At1g27730; ORFNames=T22C5.18;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY, AND INDUCTION BY
RP SALT.
RX PubMed=8662738; DOI=10.1074/jbc.271.22.12859;
RA Lippuner V., Cyert M.S., Gasser C.S.;
RT "Two classes of plant cDNA clones differentially complement yeast
RT calcineurin mutants and increase salt tolerance of wild-type yeast.";
RL J. Biol. Chem. 271:12859-12866(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], AND TISSUE SPECIFICITY.
RC STRAIN=cv. Columbia;
RX PubMed=9132053; DOI=10.1023/a:1005746803089;
RA Meissner R., Michael A.J.;
RT "Isolation and characterisation of a diverse family of Arabidopsis two and
RT three-fingered protein genes and cDNA's.";
RL Plant Mol. Biol. 33:615-624(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=10929106; DOI=10.1046/j.1365-313x.2000.00809.x;
RA Kleinow T., Bhalerao R., Breuer F., Umeda M., Salchert K., Koncz C.;
RT "Functional identification of an Arabidopsis Snf4 ortholog by screening for
RT heterologous multicopy suppressors of snf4 deficiency in yeast.";
RL Plant J. 23:115-122(2000).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [7]
RP TISSUE SPECIFICITY, AND INDUCTION.
RX PubMed=10806347; DOI=10.1016/s0378-1119(00)00133-5;
RA Sakamoto H., Araki T., Meshi T., Iwabuchi M.;
RT "Expression of a subset of the Arabidopsis Cys(2)/His(2)-type zinc-finger
RT protein gene family under water stress.";
RL Gene 248:23-32(2000).
RN [8]
RP INDUCTION.
RX PubMed=11351099; DOI=10.1104/pp.126.1.363;
RA Gong Z., Koiwa H., Cushman M.A., Ray A., Bufford D., Kore-eda S.,
RA Matsumoto T.K., Zhu J., Cushman J.C., Bressan R.A., Hasegawa P.M.;
RT "Genes that are uniquely stress regulated in salt overly sensitive (sos)
RT mutants.";
RL Plant Physiol. 126:363-375(2001).
RN [9]
RP FUNCTION.
RX PubMed=12032082; DOI=10.1093/emboj/21.11.2692;
RA Lee H., Guo Y., Ohta M., Xiong L., Stevenson B., Zhu J.K.;
RT "LOS2, a genetic locus required for cold-responsive gene transcription
RT encodes a bi-functional enolase.";
RL EMBO J. 21:2692-2702(2002).
RN [10]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND INDUCTION.
RX PubMed=15333755; DOI=10.1104/pp.104.046599;
RA Sakamoto H., Maruyama K., Sakuma Y., Meshi T., Iwabuchi M., Shinozaki K.,
RA Yamaguchi-Shinozaki K.;
RT "Arabidopsis Cys2/His2-type zinc-finger proteins function as transcription
RT repressors under drought, cold, and high-salinity stress conditions.";
RL Plant Physiol. 136:2734-2746(2004).
RN [11]
RP INDUCTION.
RX PubMed=12837949; DOI=10.1105/tpc.011650;
RA Ogawa M., Hanada A., Yamauchi Y., Kuwahara A., Kamiya Y., Yamaguchi S.;
RT "Gibberellin biosynthesis and response during Arabidopsis seed
RT germination.";
RL Plant Cell 15:1591-1604(2003).
RN [12]
RP FUNCTION, AND INDUCTION.
RX PubMed=17112521; DOI=10.1016/j.febslet.2006.11.002;
RA Mittler R., Kim Y., Song L., Coutu J., Coutu A., Ciftci-Yilmaz S., Lee H.,
RA Stevenson B., Zhu J.K.;
RT "Gain- and loss-of-function mutations in Zat10 enhance the tolerance of
RT plants to abiotic stress.";
RL FEBS Lett. 580:6537-6542(2006).
RN [13]
RP FUNCTION.
RX PubMed=18216250; DOI=10.1073/pnas.0711203105;
RA Pauwels L., Morreel K., De Witte E., Lammertyn F., Van Montagu M.,
RA Boerjan W., Inze D., Goossens A.;
RT "Mapping methyl jasmonate-mediated transcriptional reprogramming of
RT metabolism and cell cycle progression in cultured Arabidopsis cells.";
RL Proc. Natl. Acad. Sci. U.S.A. 105:1380-1385(2008).
RN [14]
RP FUNCTION.
RX PubMed=20140232; DOI=10.4161/psb.3.10.5993;
RA Pauwels L., Goossens A.;
RT "Fine-tuning of early events in the jasmonate response.";
RL Plant Signal. Behav. 3:846-847(2008).
CC -!- FUNCTION: Transcriptional repressor involved in abiotic stress
CC responses. Can repress the stress responsive genes DREB1A and LTI78.
CC Probably involved in jasmonate (JA) early signaling response. May
CC regulate the expression of the JA biosynthesis gene LOX3 and control
CC the expression of TIFY10A/JAZ1, a key repressor in the JA signaling
CC cascade. {ECO:0000269|PubMed:12032082, ECO:0000269|PubMed:15333755,
CC ECO:0000269|PubMed:17112521, ECO:0000269|PubMed:18216250,
CC ECO:0000269|PubMed:20140232, ECO:0000269|PubMed:8662738}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:15333755}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, stems and leaves.
CC {ECO:0000269|PubMed:10806347, ECO:0000269|PubMed:15333755,
CC ECO:0000269|PubMed:8662738, ECO:0000269|PubMed:9132053}.
CC -!- INDUCTION: By salt, cold and drought stresses. Down-regulated by
CC gibberellin. {ECO:0000269|PubMed:10806347, ECO:0000269|PubMed:11351099,
CC ECO:0000269|PubMed:12837949, ECO:0000269|PubMed:15333755,
CC ECO:0000269|PubMed:17112521, ECO:0000269|PubMed:8662738}.
CC -!- MISCELLANEOUS: Plants overexpressing ZAT10 show growth retardation and
CC enhanced tolerance to drought, salt, heat and osmotic stresses. Plants
CC silencing ZAT10 show enhanced tolerance to salt and osmotic stresses.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF24959.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; X95573; CAA64820.1; -; mRNA.
DR EMBL; X98670; CAA67228.1; -; mRNA.
DR EMBL; X98671; CAA67229.1; -; Genomic_DNA.
DR EMBL; AF250336; AAG10142.1; -; mRNA.
DR EMBL; AC012375; AAF24959.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE30870.1; -; Genomic_DNA.
DR EMBL; AY034998; AAK59503.1; -; mRNA.
DR EMBL; AY063006; AAL34180.1; -; mRNA.
DR RefSeq; NP_174094.1; NM_102538.3.
DR AlphaFoldDB; Q96289; -.
DR SMR; Q96289; -.
DR BioGRID; 24901; 6.
DR STRING; 3702.AT1G27730.1; -.
DR PaxDb; Q96289; -.
DR PRIDE; Q96289; -.
DR ProteomicsDB; 242942; -.
DR EnsemblPlants; AT1G27730.1; AT1G27730.1; AT1G27730.
DR GeneID; 839666; -.
DR Gramene; AT1G27730.1; AT1G27730.1; AT1G27730.
DR KEGG; ath:AT1G27730; -.
DR Araport; AT1G27730; -.
DR TAIR; locus:2199246; AT1G27730.
DR eggNOG; KOG1721; Eukaryota.
DR HOGENOM; CLU_059471_1_2_1; -.
DR InParanoid; Q96289; -.
DR OMA; VIPQRHR; -.
DR OrthoDB; 1395906at2759; -.
DR PRO; PR:Q96289; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q96289; baseline and differential.
DR Genevisible; Q96289; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IDA:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0071456; P:cellular response to hypoxia; HEP:TAIR.
DR GO; GO:0035264; P:multicellular organism growth; IMP:TAIR.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:TAIR.
DR GO; GO:0010117; P:photoprotection; IMP:TAIR.
DR GO; GO:0015979; P:photosynthesis; IMP:TAIR.
DR GO; GO:0009737; P:response to abscisic acid; IEP:TAIR.
DR GO; GO:0010200; P:response to chitin; IEP:TAIR.
DR GO; GO:0009409; P:response to cold; IEP:TAIR.
DR GO; GO:0009644; P:response to high light intensity; IEP:TAIR.
DR GO; GO:0006979; P:response to oxidative stress; IMP:TAIR.
DR GO; GO:0009651; P:response to salt stress; IEP:TAIR.
DR GO; GO:0009414; P:response to water deprivation; IMP:TAIR.
DR GO; GO:0009611; P:response to wounding; IEP:TAIR.
DR InterPro; IPR044653; AZF1/2/3-like.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR45988; PTHR45988; 1.
DR SMART; SM00355; ZnF_C2H2; 2.
DR SUPFAM; SSF57667; SSF57667; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 2.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE 2: Evidence at transcript level;
KW Metal-binding; Nucleus; Reference proteome; Repeat; Repressor;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..227
FT /note="Zinc finger protein ZAT10"
FT /id="PRO_0000409719"
FT ZN_FING 80..102
FT /note="C2H2-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 136..158
FT /note="C2H2-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT REGION 96..128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 168..189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 102..128
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 168..187
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 58
FT /note="C -> W (in Ref. 2; CAA67228/CAA67229)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 227 AA; 24614 MW; F3B70CCF695A6F54 CRC64;
MALEALTSPR LASPIPPLFE DSSVFHGVEH WTKGKRSKRS RSDFHHQNLT EEEYLAFCLM
LLARDNRQPP PPPAVEKLSY KCSVCDKTFS SYQALGGHKA SHRKNLSQTL SGGGDDHSTS
SATTTSAVTT GSGKSHVCTI CNKSFPSGQA LGGHKRCHYE GNNNINTSSV SNSEGAGSTS
HVSSSHRGFD LNIPPIPEFS MVNGDDEVMS PMPAKKPRFD FPVKLQL
