ID   ZAT7_ARATH              Reviewed;         168 AA.
AC   Q42453;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 159.
DE   RecName: Full=Zinc finger protein ZAT7;
GN   Name=ZAT7; OrderedLocusNames=At3g46090; ORFNames=F12M12.60;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], AND TISSUE SPECIFICITY.
RC   STRAIN=cv. Columbia;
RX   PubMed=9132053; DOI=10.1023/a:1005746803089;
RA   Meissner R., Michael A.J.;
RT   "Isolation and characterisation of a diverse family of Arabidopsis two and
RT   three-fingered protein genes and cDNA's.";
RL   Plant Mol. Biol. 33:615-624(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130713; DOI=10.1038/35048706;
RA   Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA   Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA   Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA   Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA   Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA   Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA   Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA   Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA   Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA   Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA   Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA   Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA   de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA   Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA   Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA   Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA   Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA   Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA   Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA   Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA   Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA   Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA   Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA   Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL   Nature 408:820-822(2000).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Kim C.J., Chen H., Shinn P., Ecker J.R.;
RT   "Arabidopsis ORF clones.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Fujita M., Mizukado S., Seki M., Shinozaki K., Mitsuda N., Takiguchi Y.,
RA   Takagi M.;
RT   "ORF cloning and analysis of Arabidopsis transcription factor genes.";
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN   [6]
RP   FUNCTION, AND INDUCTION.
RX   PubMed=14722088; DOI=10.1074/jbc.m313350200;
RA   Rizhsky L., Davletova S., Liang H., Mittler R.;
RT   "The zinc finger protein Zat12 is required for cytosolic ascorbate
RT   peroxidase 1 expression during oxidative stress in Arabidopsis.";
RL   J. Biol. Chem. 279:11736-11743(2004).
RN   [7]
RP   INDUCTION BY CUCUMBER MOSAIC VIRUS.
RX   PubMed=18922600; DOI=10.1016/j.jplph.2008.08.006;
RA   Mitsuya Y., Takahashi Y., Berberich T., Miyazaki A., Matsumura H.,
RA   Takahashi H., Terauchi R., Kusano T.;
RT   "Spermine signaling plays a significant role in the defense response of
RT   Arabidopsis thaliana to cucumber mosaic virus.";
RL   J. Plant Physiol. 166:626-643(2009).
CC   -!- FUNCTION: Probable transcription factor involved in oxidative stress
CC       response. {ECO:0000269|PubMed:14722088}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Expressed in roots, stems and leaves.
CC       {ECO:0000269|PubMed:9132053}.
CC   -!- INDUCTION: By H(2)O(2), heat stress, wounding and cucumber mosaic virus
CC       (CMV). {ECO:0000269|PubMed:14722088, ECO:0000269|PubMed:18922600}.
CC   -!- MISCELLANEOUS: Plants overexpressing ZAT7 show retarded growth and
CC       development, and enhanced tolerance to oxidative stress.
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DR   EMBL; X98676; CAA67234.1; -; mRNA.
DR   EMBL; X98677; CAA67235.1; -; Genomic_DNA.
DR   EMBL; AL355775; CAB90936.1; -; Genomic_DNA.
DR   EMBL; CP002686; AEE78112.1; -; Genomic_DNA.
DR   EMBL; BT024870; ABD65601.1; -; mRNA.
DR   EMBL; AB493641; BAH30479.1; -; mRNA.
DR   PIR; T49250; T49250.
DR   RefSeq; NP_190195.1; NM_114478.4.
DR   AlphaFoldDB; Q42453; -.
DR   BioGRID; 9072; 3.
DR   IntAct; Q42453; 47.
DR   STRING; 3702.AT3G46090.1; -.
DR   PaxDb; Q42453; -.
DR   PRIDE; Q42453; -.
DR   DNASU; 823752; -.
DR   EnsemblPlants; AT3G46090.1; AT3G46090.1; AT3G46090.
DR   GeneID; 823752; -.
DR   Gramene; AT3G46090.1; AT3G46090.1; AT3G46090.
DR   KEGG; ath:AT3G46090; -.
DR   Araport; AT3G46090; -.
DR   TAIR; locus:2075291; AT3G46090.
DR   eggNOG; KOG1721; Eukaryota.
DR   HOGENOM; CLU_059471_3_3_1; -.
DR   InParanoid; Q42453; -.
DR   OMA; TEATCLM; -.
DR   OrthoDB; 1412405at2759; -.
DR   PhylomeDB; Q42453; -.
DR   PRO; PR:Q42453; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q42453; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0071456; P:cellular response to hypoxia; HEP:TAIR.
DR   GO; GO:0045926; P:negative regulation of growth; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR   GO; GO:0010200; P:response to chitin; IBA:GO_Central.
DR   GO; GO:0006979; P:response to oxidative stress; IMP:UniProtKB.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   SMART; SM00355; ZnF_C2H2; 2.
DR   SUPFAM; SSF57667; SSF57667; 2.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 2.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE   2: Evidence at transcript level;
KW   Metal-binding; Nucleus; Reference proteome; Repeat; Transcription;
KW   Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..168
FT                   /note="Zinc finger protein ZAT7"
FT                   /id="PRO_0000409716"
FT   ZN_FING         40..62
FT                   /note="C2H2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         86..108
FT                   /note="C2H2-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
SQ   SEQUENCE   168 AA;  18359 MW;  2CF7DD7ACCE86988 CRC64;
     MVARSEEIVI VEEDTTAKCL MLLSRVGECG GGCGGDERVF RCKTCLKEFS SFQALGGHRA
     SHKKLINSDN PSLLGSLSNK KTKTSHPCPI CGVKFPMGQA LGGHMRRHRN EKVSGSLVTR
     SFLPETTTVT ALKKFSSGKR VACLDLDLDS MESLVNWKLE LGRTISWS