ID   ZB8AA_XENLA             Reviewed;         470 AA.
AC   Q0IH98;
DT   07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Zinc finger and BTB domain-containing protein 8A.1-A;
GN   Name=zbtb8a.1-a; Synonyms=zbtb8, zbtb8.1;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Neurula;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in transcriptional regulation.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
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DR   EMBL; BC123247; AAI23248.1; -; mRNA.
DR   RefSeq; NP_001090368.1; NM_001096899.1.
DR   RefSeq; XP_018100870.1; XM_018245381.1.
DR   AlphaFoldDB; Q0IH98; -.
DR   SMR; Q0IH98; -.
DR   MaxQB; Q0IH98; -.
DR   DNASU; 779279; -.
DR   GeneID; 779279; -.
DR   KEGG; xla:779279; -.
DR   CTD; 779279; -.
DR   Xenbase; XB-GENE-866345; zbtb8a.1.L.
DR   OMA; VPHYKSS; -.
DR   OrthoDB; 755439at2759; -.
DR   Proteomes; UP000186698; Chromosome 2L.
DR   Bgee; 779279; Expressed in neurula embryo and 19 other tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.710.10; -; 1.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF00096; zf-C2H2; 1.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00355; ZnF_C2H2; 2.
DR   SUPFAM; SSF54695; SSF54695; 1.
DR   SUPFAM; SSF57667; SSF57667; 1.
DR   PROSITE; PS50097; BTB; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 2.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE   2: Evidence at transcript level;
KW   DNA-binding; Metal-binding; Nucleus; Phosphoprotein; Reference proteome;
KW   Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..470
FT                   /note="Zinc finger and BTB domain-containing protein 8A.1-
FT                   A"
FT                   /id="PRO_0000378511"
FT   DOMAIN          24..92
FT                   /note="BTB"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
FT   ZN_FING         316..338
FT                   /note="C2H2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         344..367
FT                   /note="C2H2-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   REGION          260..280
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          439..470
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   470 AA;  53154 MW;  60BE8D11A2078567 CRC64;
     MEFSSHHIRL LQQLDEQRQK DLFCDCHIIV EGQMFKAHRN VLFASSGYFK MLLSQSCRDM
     GEPITATFDV FSADTFTAIL DFVYSGKLPL SGQNVIEVMS AASYLQMTDV IGVCKMFIKS
     SLDINEKDRD GFFSLSDKDA GSNGSGLYAA GWRTESSPTH THDTAEHGSF IAGYNYPPPI
     TSRLQRPFSK HPRKPELVRK HRRRLLPEPL TPAPLSHIPL GDLVGGSAEC MLHDEETVES
     VSQEEERTQT QESIISIKDE DEDAASHSWP ESPQQESLDQ GPALHITKAE ELYKAMPTML
     GGVSGWGEDE LSSGRFKCPF CTHTVKRKAD LKRHLRCHTG ERPYPCEACG KRFTRLEHLR
     NHFQTIHEAG KLICRRCKLP VTKVTGRVIQ DGTRRYRLCH ACLAEAGLDN VNFDYGEDQP
     LVLPPENERE HCWNFKEEGR KENGSERAES DLAIQEVVDS EDDELKEKQD