ID   ZB8AB_XENLA             Reviewed;         469 AA.
AC   A1L2U9;
DT   07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Zinc finger and BTB domain-containing protein 8A.1-B;
GN   Name=zbtb8a.1-b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Thymus;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in transcriptional regulation.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
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DR   EMBL; BC129718; AAI29719.1; -; mRNA.
DR   RefSeq; NP_001091193.1; NM_001097724.1.
DR   AlphaFoldDB; A1L2U9; -.
DR   SMR; A1L2U9; -.
DR   DNASU; 100036960; -.
DR   GeneID; 100036960; -.
DR   KEGG; xla:100036960; -.
DR   CTD; 100036960; -.
DR   Xenbase; XB-GENE-6255849; zbtb8a.1.S.
DR   OrthoDB; 755439at2759; -.
DR   Proteomes; UP000186698; Chromosome 2S.
DR   Bgee; 100036960; Expressed in oocyte and 19 other tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.710.10; -; 1.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF00096; zf-C2H2; 1.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00355; ZnF_C2H2; 2.
DR   SUPFAM; SSF54695; SSF54695; 1.
DR   SUPFAM; SSF57667; SSF57667; 1.
DR   PROSITE; PS50097; BTB; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 2.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE   2: Evidence at transcript level;
KW   DNA-binding; Metal-binding; Nucleus; Phosphoprotein; Reference proteome;
KW   Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..469
FT                   /note="Zinc finger and BTB domain-containing protein 8A.1-
FT                   B"
FT                   /id="PRO_0000378512"
FT   DOMAIN          24..92
FT                   /note="BTB"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
FT   ZN_FING         315..337
FT                   /note="C2H2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         343..366
FT                   /note="C2H2-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
SQ   SEQUENCE   469 AA;  52998 MW;  BA2B6D07F4AAB559 CRC64;
     MEFSSHHIRL LQQLDEQRRR DLFCDCHIIV EGQMFKAHRN VLFASSGYFK MLLSQSCRDM
     GEPITATFDV FSADTFTAIL DFVYSGKLPL SGQNVIEVMS AASYLQMTDV IGVCKMFIKS
     SLDINEKDRD GFFSLSDKDT DSNGSGLYAA GWRTESSPTH THKTTEHGSF IAGYNYPPPI
     SSRLQHPFSK SPRKPELVRK HRRRLLPEAL TPALSHIPLG DLVGGSTECM LHDEETVESV
     SQEEERTQTQ VSIISIKVED LDATSNSWPE SPPQESLDQG SALHITKAEE LYKAMPTILG
     GVSGWGEDEL SSGRFKCPFC THTVKRKADL KRHLRCHTGE RPYPCEACGK RFTRLEHLRN
     HFQTIHEAGK LICRRCKLPV TKVTGRVIQD GTRRYRLCQA CLAEAGLDNV NFDYGEDQPL
     VLPPENEREH CWNFKEEGRQ ENGSEAAESD LVIQEVVDSE EDELKQKQD