ID   ZB8AL_XENTR             Reviewed;         455 AA.
AC   Q6P882;
DT   07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 129.
DE   RecName: Full=Zinc finger and BTB domain-containing protein 8A.2;
GN   Name=zbtb8a.2; Synonyms=zbtb8.2;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Neurula;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in transcriptional regulation.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
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DR   EMBL; BC061347; AAH61347.1; -; mRNA.
DR   RefSeq; NP_989007.1; NM_203676.1.
DR   RefSeq; XP_012812095.1; XM_012956641.2.
DR   AlphaFoldDB; Q6P882; -.
DR   SMR; Q6P882; -.
DR   PaxDb; Q6P882; -.
DR   PRIDE; Q6P882; -.
DR   DNASU; 394603; -.
DR   Ensembl; ENSXETT00000057916; ENSXETP00000057916; ENSXETG00000027866.
DR   GeneID; 394603; -.
DR   KEGG; xtr:394603; -.
DR   CTD; 394603; -.
DR   Xenbase; XB-GENE-490775; zbtb8a.2.
DR   eggNOG; KOG1721; Eukaryota.
DR   HOGENOM; CLU_022356_1_1_1; -.
DR   InParanoid; Q6P882; -.
DR   OMA; HYRTIHE; -.
DR   OrthoDB; 755439at2759; -.
DR   PhylomeDB; Q6P882; -.
DR   TreeFam; TF330979; -.
DR   Proteomes; UP000008143; Chromosome 2.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000027866; Expressed in testis and 12 other tissues.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000977; F:RNA polymerase II transcription regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   Gene3D; 3.30.710.10; -; 1.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF00651; BTB; 1.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00355; ZnF_C2H2; 2.
DR   SUPFAM; SSF54695; SSF54695; 1.
DR   SUPFAM; SSF57667; SSF57667; 1.
DR   PROSITE; PS50097; BTB; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 2.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE   2: Evidence at transcript level;
KW   DNA-binding; Metal-binding; Nucleus; Phosphoprotein; Reference proteome;
KW   Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..455
FT                   /note="Zinc finger and BTB domain-containing protein 8A.2"
FT                   /id="PRO_0000378514"
FT   DOMAIN          24..92
FT                   /note="BTB"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
FT   ZN_FING         299..321
FT                   /note="C2H2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         327..350
FT                   /note="C2H2-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
SQ   SEQUENCE   455 AA;  51422 MW;  628308CF505CE452 CRC64;
     MDLPSHHSRL LRQLDEQRRR NLFCDCHIMI DGHTFRAHRN VLYASSGYFK MLLSQSSGNV
     GQPTTATFDV FSADTFTAIL DFMYSGKLNL SGQNVIEIMS AASYLQMTEV IGVCKMFIKS
     SLDINEKDRD GFLDISDKET GQQTGQCGLY STGWGMGRYH CNQPEGDIAA YLETSSCTPY
     GFCSRTDEHP SSQNSISTAT MKMLDRHNRI PQIPSSTCSP EEHLRECRIL ESDDTGCHIE
     VELPQGEETE AFLNCQTVVQ PRSRRRHSLN RATKADEVYA KIMGIKGCLG EDNLPSLHFK
     CPFCTHTVKR KADLKRHLLC HTGERPYPCQ ACGKRFTRLE HVRSHYRTIH EAGKPICRWC
     KRHVTEDSGQ VVQEGTRRFR LCNKCVAEVG VGSFPNEVDD DEPTIILSGD EDKEPTWNFH
     DGIQTSDPEI IEDVSSDVVI HKVDDSDDEI KPIIC