CC150_MOUSE
ID CC150_MOUSE Reviewed; 1110 AA.
AC Q8CDI7; E9QMC0;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 27-JUL-2011, sequence version 2.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=Coiled-coil domain-containing protein 150;
GN Name=Ccdc150;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
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DR EMBL; AK029994; BAC26722.1; -; mRNA.
DR EMBL; AC124175; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC124538; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS35564.1; -.
DR RefSeq; NP_084301.2; NM_030025.2.
DR AlphaFoldDB; Q8CDI7; -.
DR SMR; Q8CDI7; -.
DR BioGRID; 219096; 2.
DR STRING; 10090.ENSMUSP00000027128; -.
DR iPTMnet; Q8CDI7; -.
DR PhosphoSitePlus; Q8CDI7; -.
DR EPD; Q8CDI7; -.
DR jPOST; Q8CDI7; -.
DR MaxQB; Q8CDI7; -.
DR PaxDb; Q8CDI7; -.
DR PRIDE; Q8CDI7; -.
DR ProteomicsDB; 265288; -.
DR Antibodypedia; 67231; 33 antibodies from 9 providers.
DR DNASU; 78016; -.
DR Ensembl; ENSMUST00000027128; ENSMUSP00000027128; ENSMUSG00000025983.
DR GeneID; 78016; -.
DR KEGG; mmu:78016; -.
DR UCSC; uc007azo.1; mouse.
DR CTD; 284992; -.
DR MGI; MGI:1925266; Ccdc150.
DR VEuPathDB; HostDB:ENSMUSG00000025983; -.
DR eggNOG; ENOG502QRGC; Eukaryota.
DR GeneTree; ENSGT00390000005285; -.
DR HOGENOM; CLU_004802_0_0_1; -.
DR InParanoid; Q8CDI7; -.
DR OMA; AQEKCNL; -.
DR OrthoDB; 624497at2759; -.
DR PhylomeDB; Q8CDI7; -.
DR TreeFam; TF338017; -.
DR BioGRID-ORCS; 78016; 2 hits in 74 CRISPR screens.
DR PRO; PR:Q8CDI7; -.
DR Proteomes; UP000000589; Chromosome 1.
DR RNAct; Q8CDI7; protein.
DR Bgee; ENSMUSG00000025983; Expressed in spermatid and 26 other tissues.
DR ExpressionAtlas; Q8CDI7; baseline and differential.
DR Genevisible; Q8CDI7; MM.
DR InterPro; IPR038807; CCDC150.
DR PANTHER; PTHR35352; PTHR35352; 2.
PE 2: Evidence at transcript level;
KW Coiled coil; Reference proteome.
FT CHAIN 1..1110
FT /note="Coiled-coil domain-containing protein 150"
FT /id="PRO_0000328985"
FT COILED 122..250
FT /evidence="ECO:0000255"
FT COILED 288..313
FT /evidence="ECO:0000255"
FT COILED 413..695
FT /evidence="ECO:0000255"
FT COILED 728..1048
FT /evidence="ECO:0000255"
FT CONFLICT 496
FT /note="V -> I (in Ref. 1; BAC26722)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 1110 AA; 128502 MW; 2380A7BFA9FA63D1 CRC64;
METNLLPGGP SYGLLDESGV QMETTVCRPV LSPTHINGTA SETFTVLQQK MRIVEEQTSS
LRDDLIMLGY GDRRGQLETP NYLEDPASQK AISPIPNEVI CPESPGNLWR NYEFLVNRMC
YLENLIQSLK MNIFHLQTEK ESNPQKTAFL NDQLNIIQGE HSKGLKLLQL EVMNLRQQLK
VVKEEEDRAQ DEMQRLTATL EIATETKKNA AVIEEELKTT KRKMNLKIQE LRRQLAQEKL
VRESLETSAS SMLLKVQEMG SVVEAERQQV HALQEKCTAL HSSMKTTQDL LAQEQRKNED
LGMTISQLKS DLNSRDNLIC KLVEENKATQ ISLKKEHEEN IYLKSEILSL QDVSGKAQVL
NDQLSKKCSE LTSMLQVVKM ENSRIIAEHQ AILKVEQKMI TETFQEQNLL LDAAHASITG
ELQAVQNEKA QLQIHLDHLI LEHNQCLQKS QEAEKRTVVQ KELLESTIAR LQGELKASLQ
EKKSLLEKNE WFQREVNKTE KEVAKEKCNL EKELAESKED INVLNQNLQT LMEENKHLTN
KMASLEHHKA TSDYQGKVEK ALEKITDSKN MLAYEKGKLQ TKVKQLEAQL HTFAETMLQK
DHLHKLNKAL EVKYTQANSE LSASKAYLEQ TEAHLKEMKS ILGKNEEELA QAVKCRDAAL
KESQKLKGDL KALEDRESKK VGNFQKQLAE AKEDNCKVTI MLENVLASHS KMQGALEKVQ
IELGRRDSEI AGLKKERSLN QQRVQKLEAE VDQWQARMLI VEAQHGSEIE PLQKSLDITR
EDNRKLAMSL EQALQTNGHL QSKLDHLQEK LESKERERQS LEAFKEQVAE ESKVEAELHA
ERIEALRKQF QTERETAKKA SQREVSELKK ALDEANFRSV EVSRANRELR HKATELEKVV
NSNKEKLKNQ RAQIKLHLSA KANNAQNMER MKQIEMELRQ MEIIKDQYQK KNYEQSLSIQ
RFVSEMNTLQ KEMELLTKSQ YETSARNKQQ ELRLVAERKM RLELENRCKE LEETIRHLKR
CKEATENKLK EASVESEQIT ANLEEAHRWF KCRFDGLQLE LTKNRLQRLP REDRWLEENQ
DMMHNVATSQ SVLHRWETKQ KYHSDTERKK
