ID   ZBT44_XENTR             Reviewed;         448 AA.
AC   Q0P4X6;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Zinc finger and BTB domain-containing protein 44;
GN   Name=zbtb44;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; BC121859; AAI21860.1; -; mRNA.
DR   RefSeq; NP_001072459.1; NM_001078991.1.
DR   AlphaFoldDB; Q0P4X6; -.
DR   SMR; Q0P4X6; -.
DR   STRING; 8364.ENSXETP00000038830; -.
DR   PaxDb; Q0P4X6; -.
DR   GeneID; 779914; -.
DR   KEGG; xtr:779914; -.
DR   CTD; 29068; -.
DR   Xenbase; XB-GENE-1033035; zbtb44.
DR   eggNOG; KOG1721; Eukaryota.
DR   InParanoid; Q0P4X6; -.
DR   Proteomes; UP000008143; Chromosome 7.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.710.10; -; 1.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF00096; zf-C2H2; 2.
DR   SMART; SM00225; BTB; 1.
DR   SMART; SM00355; ZnF_C2H2; 2.
DR   SUPFAM; SSF54695; SSF54695; 1.
DR   SUPFAM; SSF57667; SSF57667; 1.
DR   PROSITE; PS50097; BTB; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 2.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE   2: Evidence at transcript level;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..448
FT                   /note="Zinc finger and BTB domain-containing protein 44"
FT                   /id="PRO_0000274611"
FT   DOMAIN          31..98
FT                   /note="BTB"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
FT   ZN_FING         394..416
FT                   /note="C2H2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         422..444
FT                   /note="C2H2-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   REGION          289..320
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        299..320
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   448 AA;  50009 MW;  934CEBE127EB74BE CRC64;
     MGVKTFTHNS PGHSQEMLGK LNMLRNDGHF CDITIRVQDK IFRAHKVVLA ACSEFFRTKL
     VGQAEDSSQC VLDLHHVTVT GFTPLLEYAY TATLSINTEN IIDVLAAASY MQMFSVASTC
     SEFMKSSILW NTQQEKILDT GQENPVNCNN FRDGSLSPVS SECSVVERTI PICRESRRKR
     KSYIVMSPES PLKCNTQTSS PQVLNPTPSY AEARNQSVDS SHAFPWTFPF GIDRRIQSEK
     VKQIESRTLE LPGPSEVARR VTDYVACEST KVSSPLVMED DVRVKVERLS DEEVHEEVSQ
     PVSASQSSMS DQQTVPGSEQ VQEDLLISPQ SSSIGSIDEG VSEGLPTLQS TASTSVHADD
     DDRLENVQYP YQLYLAPTTS STERPSPNGP DRPFQCPTCG VRFTRIQNLK QHMLIHSGIK
     PFQCDRCGKK FTRAYSLKMH RLKHEAIS