ZC21C_HUMAN
ID ZC21C_HUMAN Reviewed; 456 AA.
AC Q53FD0; E9PJQ0; Q9BTA8; Q9H5S9;
DT 30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 16-MAY-2012, sequence version 3.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=Zinc finger C2HC domain-containing protein 1C;
GN Name=ZC2HC1C; Synonyms=C14orf140, FAM164C;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC TISSUE=Lung;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC TISSUE=Testis;
RA Suzuki Y., Sugano S., Totoki Y., Toyoda A., Takeda T., Sakaki Y.,
RA Tanaka A., Yokoyama S.;
RL Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12508121; DOI=10.1038/nature01348;
RA Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C.,
RA Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A.,
RA Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H.,
RA Du H., Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T.,
RA Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B.,
RA Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D.,
RA Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R.,
RA Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S.,
RA Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C.,
RA Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S.,
RA Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C.,
RA Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P.,
RA Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M.,
RA Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V.,
RA Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J.,
RA Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F.,
RA Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F.,
RA Waterston R., Hood L., Weissenbach J.;
RT "The DNA sequence and analysis of human chromosome 14.";
RL Nature 421:601-607(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC TISSUE=Uterus;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- INTERACTION:
CC Q53FD0; Q8N9N5: BANP; NbExp=3; IntAct=EBI-740767, EBI-744695;
CC Q53FD0; Q8NA61: CBY2; NbExp=3; IntAct=EBI-740767, EBI-741724;
CC Q53FD0; Q96JN2-2: CCDC136; NbExp=3; IntAct=EBI-740767, EBI-10171416;
CC Q53FD0; Q9Y6C2: EMILIN1; NbExp=3; IntAct=EBI-740767, EBI-744586;
CC Q53FD0; A1L4K1: FSD2; NbExp=3; IntAct=EBI-740767, EBI-5661036;
CC Q53FD0; P14136: GFAP; NbExp=3; IntAct=EBI-740767, EBI-744302;
CC Q53FD0; Q96ED9: HOOK2; NbExp=3; IntAct=EBI-740767, EBI-743290;
CC Q53FD0; P19012: KRT15; NbExp=4; IntAct=EBI-740767, EBI-739566;
CC Q53FD0; Q6A162: KRT40; NbExp=3; IntAct=EBI-740767, EBI-10171697;
CC Q53FD0; Q9UJV3-2: MID2; NbExp=3; IntAct=EBI-740767, EBI-10172526;
CC Q53FD0; Q5JR59: MTUS2; NbExp=4; IntAct=EBI-740767, EBI-742948;
CC Q53FD0; Q8ND90: PNMA1; NbExp=4; IntAct=EBI-740767, EBI-302345;
CC Q53FD0; Q9UJ41: RABGEF1; NbExp=3; IntAct=EBI-740767, EBI-913954;
CC Q53FD0; P31947: SFN; NbExp=3; IntAct=EBI-740767, EBI-476295;
CC Q53FD0; Q96R06: SPAG5; NbExp=3; IntAct=EBI-740767, EBI-413317;
CC Q53FD0; Q9UBB9: TFIP11; NbExp=4; IntAct=EBI-740767, EBI-1105213;
CC Q53FD0; Q13077: TRAF1; NbExp=3; IntAct=EBI-740767, EBI-359224;
CC Q53FD0; Q12933: TRAF2; NbExp=3; IntAct=EBI-740767, EBI-355744;
CC Q53FD0; P36406: TRIM23; NbExp=3; IntAct=EBI-740767, EBI-740098;
CC Q53FD0; P14373: TRIM27; NbExp=3; IntAct=EBI-740767, EBI-719493;
CC Q53FD0-2; P35609: ACTN2; NbExp=3; IntAct=EBI-14104088, EBI-77797;
CC Q53FD0-2; Q49AR9: ANKS1A; NbExp=3; IntAct=EBI-14104088, EBI-11954519;
CC Q53FD0-2; Q9H6L4: ARMC7; NbExp=3; IntAct=EBI-14104088, EBI-742909;
CC Q53FD0-2; Q8TD16-2: BICD2; NbExp=3; IntAct=EBI-14104088, EBI-11975051;
CC Q53FD0-2; Q13895: BYSL; NbExp=3; IntAct=EBI-14104088, EBI-358049;
CC Q53FD0-2; Q5BKX5-3: C19orf54; NbExp=3; IntAct=EBI-14104088, EBI-11976299;
CC Q53FD0-2; Q9NP86: CABP5; NbExp=3; IntAct=EBI-14104088, EBI-10311131;
CC Q53FD0-2; Q9H257-2: CARD9; NbExp=3; IntAct=EBI-14104088, EBI-11530605;
CC Q53FD0-2; P55212: CASP6; NbExp=3; IntAct=EBI-14104088, EBI-718729;
CC Q53FD0-2; Q68D86: CCDC102B; NbExp=6; IntAct=EBI-14104088, EBI-10171570;
CC Q53FD0-2; Q2TAC2-2: CCDC57; NbExp=3; IntAct=EBI-14104088, EBI-10961624;
CC Q53FD0-2; A6NC98: CCDC88B; NbExp=3; IntAct=EBI-14104088, EBI-347573;
CC Q53FD0-2; P06307: CCK; NbExp=3; IntAct=EBI-14104088, EBI-6624398;
CC Q53FD0-2; P28329-3: CHAT; NbExp=3; IntAct=EBI-14104088, EBI-25837549;
CC Q53FD0-2; Q96Q77: CIB3; NbExp=3; IntAct=EBI-14104088, EBI-10292696;
CC Q53FD0-2; O95833: CLIC3; NbExp=3; IntAct=EBI-14104088, EBI-10192241;
CC Q53FD0-2; Q9BSW2: CRACR2A; NbExp=3; IntAct=EBI-14104088, EBI-739773;
CC Q53FD0-2; P26196: DDX6; NbExp=3; IntAct=EBI-14104088, EBI-351257;
CC Q53FD0-2; Q01658: DR1; NbExp=3; IntAct=EBI-14104088, EBI-750300;
CC Q53FD0-2; Q9Y6C2-2: EMILIN1; NbExp=3; IntAct=EBI-14104088, EBI-11748557;
CC Q53FD0-2; Q9H0I2: ENKD1; NbExp=3; IntAct=EBI-14104088, EBI-744099;
CC Q53FD0-2; Q86YD7: FAM90A1; NbExp=3; IntAct=EBI-14104088, EBI-6658203;
CC Q53FD0-2; Q9NVK5-3: FGFR1OP2; NbExp=3; IntAct=EBI-14104088, EBI-12377025;
CC Q53FD0-2; P22607: FGFR3; NbExp=3; IntAct=EBI-14104088, EBI-348399;
CC Q53FD0-2; P14136: GFAP; NbExp=3; IntAct=EBI-14104088, EBI-744302;
CC Q53FD0-2; Q92805: GOLGA1; NbExp=3; IntAct=EBI-14104088, EBI-6164177;
CC Q53FD0-2; Q08379: GOLGA2; NbExp=3; IntAct=EBI-14104088, EBI-618309;
CC Q53FD0-2; Q9NYA3: GOLGA6A; NbExp=3; IntAct=EBI-14104088, EBI-11163335;
CC Q53FD0-2; Q96D09: GPRASP2; NbExp=3; IntAct=EBI-14104088, EBI-473189;
CC Q53FD0-2; Q14957: GRIN2C; NbExp=3; IntAct=EBI-14104088, EBI-8285963;
CC Q53FD0-2; Q9Y5Q9: GTF3C3; NbExp=3; IntAct=EBI-14104088, EBI-1054873;
CC Q53FD0-2; O00291: HIP1; NbExp=3; IntAct=EBI-14104088, EBI-473886;
CC Q53FD0-2; Q5SUL5: HLA-A; NbExp=3; IntAct=EBI-14104088, EBI-8561769;
CC Q53FD0-2; P30519: HMOX2; NbExp=3; IntAct=EBI-14104088, EBI-712096;
CC Q53FD0-2; Q96ED9-2: HOOK2; NbExp=3; IntAct=EBI-14104088, EBI-10961706;
CC Q53FD0-2; O75031: HSF2BP; NbExp=3; IntAct=EBI-14104088, EBI-7116203;
CC Q53FD0-2; P42858: HTT; NbExp=3; IntAct=EBI-14104088, EBI-466029;
CC Q53FD0-2; Q8WXH2: JPH3; NbExp=3; IntAct=EBI-14104088, EBI-1055254;
CC Q53FD0-2; Q8N6L0: KASH5; NbExp=3; IntAct=EBI-14104088, EBI-749265;
CC Q53FD0-2; Q92993: KAT5; NbExp=6; IntAct=EBI-14104088, EBI-399080;
CC Q53FD0-2; Q9H079: KATNBL1; NbExp=3; IntAct=EBI-14104088, EBI-715394;
CC Q53FD0-2; O60333-2: KIF1B; NbExp=3; IntAct=EBI-14104088, EBI-10975473;
CC Q53FD0-2; Q9HAQ2: KIF9; NbExp=3; IntAct=EBI-14104088, EBI-8472129;
CC Q53FD0-2; P19012: KRT15; NbExp=3; IntAct=EBI-14104088, EBI-739566;
CC Q53FD0-2; P13473-2: LAMP2; NbExp=3; IntAct=EBI-14104088, EBI-21591415;
CC Q53FD0-2; Q03252: LMNB2; NbExp=3; IntAct=EBI-14104088, EBI-2830427;
CC Q53FD0-2; Q8TAP4-4: LMO3; NbExp=3; IntAct=EBI-14104088, EBI-11742507;
CC Q53FD0-2; Q9BRK4: LZTS2; NbExp=3; IntAct=EBI-14104088, EBI-741037;
CC Q53FD0-2; P45984: MAPK9; NbExp=3; IntAct=EBI-14104088, EBI-713568;
CC Q53FD0-2; Q9UPY8: MAPRE3; NbExp=3; IntAct=EBI-14104088, EBI-726739;
CC Q53FD0-2; Q9NZQ3-3: NCKIPSD; NbExp=3; IntAct=EBI-14104088, EBI-10963850;
CC Q53FD0-2; Q9GZM8: NDEL1; NbExp=3; IntAct=EBI-14104088, EBI-928842;
CC Q53FD0-2; Q9UHB4: NDOR1; NbExp=3; IntAct=EBI-14104088, EBI-10249760;
CC Q53FD0-2; I6L9F6: NEFL; NbExp=3; IntAct=EBI-14104088, EBI-10178578;
CC Q53FD0-2; P07196: NEFL; NbExp=3; IntAct=EBI-14104088, EBI-475646;
CC Q53FD0-2; Q9HC98-4: NEK6; NbExp=3; IntAct=EBI-14104088, EBI-11750983;
CC Q53FD0-2; Q86UR1-2: NOXA1; NbExp=3; IntAct=EBI-14104088, EBI-12025760;
CC Q53FD0-2; Q96HA8: NTAQ1; NbExp=3; IntAct=EBI-14104088, EBI-741158;
CC Q53FD0-2; Q9UJX0: OSGIN1; NbExp=3; IntAct=EBI-14104088, EBI-9057006;
CC Q53FD0-2; Q99471: PFDN5; NbExp=3; IntAct=EBI-14104088, EBI-357275;
CC Q53FD0-2; Q4G0R1: PIBF1; NbExp=3; IntAct=EBI-14104088, EBI-14066006;
CC Q53FD0-2; O15160: POLR1C; NbExp=3; IntAct=EBI-14104088, EBI-1055079;
CC Q53FD0-2; P62937-2: PPIA; NbExp=3; IntAct=EBI-14104088, EBI-25884072;
CC Q53FD0-2; O43741: PRKAB2; NbExp=3; IntAct=EBI-14104088, EBI-1053424;
CC Q53FD0-2; P41219: PRPH; NbExp=3; IntAct=EBI-14104088, EBI-752074;
CC Q53FD0-2; O43586: PSTPIP1; NbExp=3; IntAct=EBI-14104088, EBI-1050964;
CC Q53FD0-2; O75771: RAD51D; NbExp=3; IntAct=EBI-14104088, EBI-1055693;
CC Q53FD0-2; P62826: RAN; NbExp=3; IntAct=EBI-14104088, EBI-286642;
CC Q53FD0-2; Q6NUQ1: RINT1; NbExp=3; IntAct=EBI-14104088, EBI-726876;
CC Q53FD0-2; Q9Y3C5: RNF11; NbExp=3; IntAct=EBI-14104088, EBI-396669;
CC Q53FD0-2; Q15047-2: SETDB1; NbExp=3; IntAct=EBI-14104088, EBI-9090795;
CC Q53FD0-2; Q9Y371: SH3GLB1; NbExp=3; IntAct=EBI-14104088, EBI-2623095;
CC Q53FD0-2; Q9BRV8: SIKE1; NbExp=6; IntAct=EBI-14104088, EBI-1773646;
CC Q53FD0-2; Q96GM5: SMARCD1; NbExp=3; IntAct=EBI-14104088, EBI-358489;
CC Q53FD0-2; O60504: SORBS3; NbExp=3; IntAct=EBI-14104088, EBI-741237;
CC Q53FD0-2; O14787-2: TNPO2; NbExp=3; IntAct=EBI-14104088, EBI-12076664;
CC Q53FD0-2; Q12933: TRAF2; NbExp=3; IntAct=EBI-14104088, EBI-355744;
CC Q53FD0-2; P36406: TRIM23; NbExp=3; IntAct=EBI-14104088, EBI-740098;
CC Q53FD0-2; P57075-2: UBASH3A; NbExp=3; IntAct=EBI-14104088, EBI-7353612;
CC Q53FD0-2; Q9UMX0: UBQLN1; NbExp=3; IntAct=EBI-14104088, EBI-741480;
CC Q53FD0-2; Q8N1B4: VPS52; NbExp=3; IntAct=EBI-14104088, EBI-2799833;
CC Q53FD0-2; O76024: WFS1; NbExp=3; IntAct=EBI-14104088, EBI-720609;
CC Q53FD0-2; P61981: YWHAG; NbExp=3; IntAct=EBI-14104088, EBI-359832;
CC Q53FD0-2; Q8N720: ZNF655; NbExp=5; IntAct=EBI-14104088, EBI-625509;
CC Q53FD0-2; P36508: ZNF76; NbExp=3; IntAct=EBI-14104088, EBI-7254550;
CC Q53FD0-2; Q9Y649; NbExp=3; IntAct=EBI-14104088, EBI-25900580;
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q53FD0-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q53FD0-2; Sequence=VSP_043105;
CC -!- SIMILARITY: Belongs to the ZC2HC1 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB15541.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AK026746; BAB15541.1; ALT_FRAME; mRNA.
DR EMBL; AK223359; BAD97079.1; -; mRNA.
DR EMBL; AL049780; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC004259; AAH04259.1; -; mRNA.
DR CCDS; CCDS41972.1; -. [Q53FD0-1]
DR CCDS; CCDS45138.1; -. [Q53FD0-2]
DR RefSeq; NP_001035895.1; NM_001042430.2. [Q53FD0-2]
DR RefSeq; NP_078919.2; NM_024643.3. [Q53FD0-1]
DR RefSeq; XP_005268119.1; XM_005268062.3. [Q53FD0-1]
DR RefSeq; XP_011535457.1; XM_011537155.2. [Q53FD0-1]
DR RefSeq; XP_011535458.1; XM_011537156.2. [Q53FD0-1]
DR RefSeq; XP_016877133.1; XM_017021644.1. [Q53FD0-2]
DR RefSeq; XP_016877134.1; XM_017021645.1. [Q53FD0-2]
DR AlphaFoldDB; Q53FD0; -.
DR SMR; Q53FD0; -.
DR BioGRID; 122817; 102.
DR IntAct; Q53FD0; 107.
DR MINT; Q53FD0; -.
DR STRING; 9606.ENSP00000435550; -.
DR iPTMnet; Q53FD0; -.
DR PhosphoSitePlus; Q53FD0; -.
DR BioMuta; ZC2HC1C; -.
DR DMDM; 387912891; -.
DR MassIVE; Q53FD0; -.
DR PaxDb; Q53FD0; -.
DR PeptideAtlas; Q53FD0; -.
DR PRIDE; Q53FD0; -.
DR ProteomicsDB; 62464; -. [Q53FD0-1]
DR ProteomicsDB; 62465; -. [Q53FD0-2]
DR Antibodypedia; 25790; 57 antibodies from 19 providers.
DR DNASU; 79696; -.
DR Ensembl; ENST00000439583.2; ENSP00000390606.2; ENSG00000119703.15. [Q53FD0-2]
DR Ensembl; ENST00000524913.3; ENSP00000435550.1; ENSG00000119703.15. [Q53FD0-1]
DR Ensembl; ENST00000525046.2; ENSP00000435684.2; ENSG00000119703.15. [Q53FD0-2]
DR Ensembl; ENST00000526130.2; ENSP00000437160.2; ENSG00000119703.15. [Q53FD0-2]
DR Ensembl; ENST00000554763.2; ENSP00000451195.2; ENSG00000119703.15. [Q53FD0-2]
DR Ensembl; ENST00000673981.1; ENSP00000501014.1; ENSG00000119703.15. [Q53FD0-2]
DR Ensembl; ENST00000674017.1; ENSP00000501062.1; ENSG00000119703.15. [Q53FD0-2]
DR Ensembl; ENST00000674086.1; ENSP00000501056.1; ENSG00000119703.15. [Q53FD0-1]
DR Ensembl; ENST00000674097.1; ENSP00000501052.1; ENSG00000119703.15. [Q53FD0-2]
DR GeneID; 79696; -.
DR KEGG; hsa:79696; -.
DR MANE-Select; ENST00000524913.3; ENSP00000435550.1; NM_024643.4; NP_078919.2.
DR UCSC; uc001xrh.5; human. [Q53FD0-1]
DR CTD; 79696; -.
DR DisGeNET; 79696; -.
DR GeneCards; ZC2HC1C; -.
DR HGNC; HGNC:20354; ZC2HC1C.
DR HPA; ENSG00000119703; Tissue enhanced (epididymis, testis).
DR neXtProt; NX_Q53FD0; -.
DR OpenTargets; ENSG00000119703; -.
DR PharmGKB; PA162386996; -.
DR VEuPathDB; HostDB:ENSG00000119703; -.
DR eggNOG; KOG3940; Eukaryota.
DR GeneTree; ENSGT00940000160947; -.
DR HOGENOM; CLU_039058_0_0_1; -.
DR InParanoid; Q53FD0; -.
DR OMA; ERHSNVC; -.
DR OrthoDB; 1123751at2759; -.
DR PhylomeDB; Q53FD0; -.
DR TreeFam; TF319585; -.
DR PathwayCommons; Q53FD0; -.
DR SignaLink; Q53FD0; -.
DR BioGRID-ORCS; 79696; 3 hits in 1081 CRISPR screens.
DR GenomeRNAi; 79696; -.
DR Pharos; Q53FD0; Tdark.
DR PRO; PR:Q53FD0; -.
DR Proteomes; UP000005640; Chromosome 14.
DR RNAct; Q53FD0; protein.
DR Bgee; ENSG00000119703; Expressed in left testis and 104 other tissues.
DR ExpressionAtlas; Q53FD0; baseline and differential.
DR Genevisible; Q53FD0; HS.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR026104; ZNF_C2HC_dom_1C.
DR PANTHER; PTHR14649; PTHR14649; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Coiled coil; Metal-binding; Reference proteome; Zinc;
KW Zinc-finger.
FT CHAIN 1..456
FT /note="Zinc finger C2HC domain-containing protein 1C"
FT /id="PRO_0000089940"
FT ZN_FING 387..411
FT /note="C2HC-type"
FT REGION 16..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 85..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 336..388
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 211..265
FT /evidence="ECO:0000255"
FT COMPBIAS 25..46
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 357..386
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 276..456
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:14702039,
FT ECO:0000303|PubMed:15489334, ECO:0000303|Ref.2"
FT /id="VSP_043105"
FT CONFLICT 72
FT /note="P -> L (in Ref. 2; BAD97079)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 456 AA; 51658 MW; F7BD49C093D2AC2B CRC64;
MAGLQRLASH LPVGVMLPHN TTEAPGPHSA KQDSYEQGDS SQQSLKGHLR NNFQKQLLSN
KELILDKVYT HPKWNTQTKA RSYSYPHCTG ISQQDPESDS QGQGNGLFYS SGPQSWYPKA
NNQDFIPFTK KRVGVDRAFP LKPMVHRKSC STGEAGTDGD HNVYPRPPEP REFSSRNFGV
RNQGNFSVVG TVLAATQAEK AVANFDRTEW VQIRRLEAAG ESLEEEIRRK QILLRGKLKK
TEEELRRIQT QKEQAKENEN GELQKIILPR SRVKGNKSNT MYKPIFSPEF EFEEEFSRDR
REDETWGRSQ QNSGPFQFSD YRIQRLKRER LVASNNKIRD PVSEPSVEKF SPPSETPVGA
LQGSARNSSL SMAPDSSGSS GSIEEPQLGE CSHCGRKFLS FRLERHSNIC SRMRGSKRKV
FDSSRARAKG TELEQYLNWK GPASAKAEPP QKSNWR
