ID   ZC3C1_XENLA             Reviewed;         477 AA.
AC   Q6P7H4;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=Zinc finger C3HC-type protein 1-like;
DE   AltName: Full=NIPA-like protein;
GN   Name=zc3hc1; Synonyms=nipa;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable component of a SCF-type E3 ligase complex,
CC       SCF(NIPA), a complex that controls mitotic entry by mediating
CC       ubiquitination and subsequent degradation of cyclin B1 (CCNB1).
CC       {ECO:0000250}.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC   -!- SUBUNIT: Probable component of a SCF(NIPA) E3 complex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; BC061669; AAH61669.1; -; mRNA.
DR   RefSeq; NP_001083590.1; NM_001090121.1.
DR   AlphaFoldDB; Q6P7H4; -.
DR   MaxQB; Q6P7H4; -.
DR   DNASU; 399009; -.
DR   GeneID; 399009; -.
DR   KEGG; xla:399009; -.
DR   CTD; 399009; -.
DR   Xenbase; XB-GENE-948891; zc3hc1.L.
DR   OrthoDB; 1626741at2759; -.
DR   UniPathway; UPA00143; -.
DR   Proteomes; UP000186698; Chromosome 3L.
DR   Bgee; 399009; Expressed in neurula embryo and 19 other tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR013909; NIPA/Rsm1.
DR   InterPro; IPR012935; Znf_C3HC-like.
DR   Pfam; PF08600; Rsm1; 2.
DR   Pfam; PF07967; zf-C3HC; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Metal-binding; Mitosis; Nucleus;
KW   Reference proteome; Ubl conjugation pathway; Zinc; Zinc-finger.
FT   CHAIN           1..477
FT                   /note="Zinc finger C3HC-type protein 1-like"
FT                   /id="PRO_0000096852"
FT   ZN_FING         95..149
FT                   /note="C3HC-type"
FT   REGION          163..203
FT                   /note="F-box-like"
FT   REGION          287..392
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        353..367
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   477 AA;  53291 MW;  9DD7692C7DFC6E44 CRC64;
     MATTCEEVLV SPVKSTAVTP LKIRELINEG IVCGERSGIG RKEASETPEE NTAFEDLPGN
     NSYESTSKDA FFSRVESFSS LKWAGKPPEL CPLICAKYGW CNIECDMLKC SSCNAYLCAS
     LQPILDFSKY KQRCVELQEA LRKAHEKFCF WPDSPCPEHF WALLVTEPSS VLSDFVERFH
     NLCHLEMQLP SLKHEDVKSM DITEDTVSRL LRLIEDELKP KEGREANSHS LPSDSLQVHI
     SACILALCGW NTSFSSGSLC IINCPRCMRK VGLWAFQQLE TVELDNSLSA PGTPVSPAEG
     HERSPLGFMS PSRRVTRSRD AEQSPAFAYG RTRSSDLLSP ADSEAVRNRP VTRSMGQGEN
     TGLGNELHSS PHRRAKRPRL CSSSSSDTSP RSCFDPLSQH RSWCPWVNVC QASGTNTMGS
     EIQEEARRKE YGWKEVLKVL LAEENSRTIS NPDTSSVPEK SHKVFRIFRQ WQLAASS