ID   ZC3C1_XENTR             Reviewed;         478 AA.
AC   Q5M8S7;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=Zinc finger C3HC-type protein 1-like;
DE   AltName: Full=NIPA-like protein;
GN   Name=zc3hc1; Synonyms=nipa;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable component of a SCF-type E3 ligase complex,
CC       SCF(NIPA), a complex that controls mitotic entry by mediating
CC       ubiquitination and subsequent degradation of cyclin B1 (CCNB1).
CC       {ECO:0000250}.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC   -!- SUBUNIT: Probable component of a SCF(NIPA) E3 complex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; BC087863; AAH87863.1; -; mRNA.
DR   RefSeq; NP_001011259.1; NM_001011259.1.
DR   AlphaFoldDB; Q5M8S7; -.
DR   STRING; 8364.ENSXETP00000059993; -.
DR   PaxDb; Q5M8S7; -.
DR   DNASU; 496709; -.
DR   GeneID; 496709; -.
DR   KEGG; xtr:496709; -.
DR   CTD; 51530; -.
DR   Xenbase; XB-GENE-948885; zc3hc1.
DR   eggNOG; KOG4765; Eukaryota.
DR   InParanoid; Q5M8S7; -.
DR   OrthoDB; 1626741at2759; -.
DR   UniPathway; UPA00143; -.
DR   Proteomes; UP000008143; Chromosome 3.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR013909; NIPA/Rsm1.
DR   InterPro; IPR012935; Znf_C3HC-like.
DR   Pfam; PF08600; Rsm1; 2.
DR   Pfam; PF07967; zf-C3HC; 1.
PE   2: Evidence at transcript level;
KW   Cell cycle; Cell division; Metal-binding; Mitosis; Nucleus;
KW   Reference proteome; Ubl conjugation pathway; Zinc; Zinc-finger.
FT   CHAIN           1..478
FT                   /note="Zinc finger C3HC-type protein 1-like"
FT                   /id="PRO_0000096853"
FT   ZN_FING         93..147
FT                   /note="C3HC-type"
FT   REGION          161..201
FT                   /note="F-box-like"
FT   REGION          285..389
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        350..366
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        373..389
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   478 AA;  53190 MW;  41222717CC710C55 CRC64;
     MATSCEDVSP VKSPAVTPLK IRELINEGIV TGERSSIGRK ETAVVPEENN GFEDPLSNSS
     YESTSKDAFF GRVESFSSLK WAGKPSELCP LICAKYGWSN IECDMLKCSS CNAYLCASLQ
     PVLDFSKYKQ RCVELQEALR KAHEKFCFWP DSPCPDYFWA LMVTEPSSVL SDFVGRFDNL
     CHLEIQLPSI KHEDLKNMDI TEETVSHLLR LIEDELKSKD GREDNSRLAS DSLQVHISAC
     ILALCGWSTS YTSGSLCIIN CPRCMRKVGL WAFQQLEAVE LDNSLSAPNT PVSPAEGHER
     SPFGIMSPNR RVTRSRDAEQ SPALAYGRTR SSDLLSPADS EAVRSRPVTR SMGQGESSGL
     SNELHSSPLR RSKRPRLCSS SSSDTSPRGC FDPLSQHRSW CPWVNVCQAS ETSTLGSEIQ
     EEASRKEYGW KEVLNVLLAE ENSRTLSDPD TSSVPEKSHK VFRIFRQWQM AASASENP