ID   ZC3HE_CHICK             Reviewed;         730 AA.
AC   Q5F3Z9;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Zinc finger CCCH domain-containing protein 14;
GN   Name=ZC3H14; ORFNames=RCJMB04_4a10;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: May bind to RNA. {ECO:0000250|UniProtKB:Q6PJT7}.
CC   -!- SUBCELLULAR LOCATION: Nucleus speckle {ECO:0000250|UniProtKB:Q8BJ05}.
CC       Note=Colocalizes with poly(A) RNA in nuclear speckles.
CC       {ECO:0000250|UniProtKB:Q8BJ05}.
CC   -!- SIMILARITY: Belongs to the ZC3H14 family. {ECO:0000305}.
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DR   EMBL; AJ851501; CAH65135.1; -; mRNA.
DR   RefSeq; NP_001012604.1; NM_001012586.2.
DR   AlphaFoldDB; Q5F3Z9; -.
DR   STRING; 9031.ENSGALP00000036845; -.
DR   PaxDb; Q5F3Z9; -.
DR   GeneID; 423399; -.
DR   KEGG; gga:423399; -.
DR   CTD; 79882; -.
DR   VEuPathDB; HostDB:geneid_423399; -.
DR   eggNOG; KOG3702; Eukaryota.
DR   InParanoid; Q5F3Z9; -.
DR   OrthoDB; 893844at2759; -.
DR   PhylomeDB; Q5F3Z9; -.
DR   PRO; PR:Q5F3Z9; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0016607; C:nuclear speck; ISS:UniProtKB.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008143; F:poly(A) binding; IBA:GO_Central.
DR   GO; GO:1900364; P:negative regulation of mRNA polyadenylation; IBA:GO_Central.
DR   GO; GO:0043488; P:regulation of mRNA stability; IBA:GO_Central.
DR   InterPro; IPR040366; Nab2/ZC3H14.
DR   InterPro; IPR000571; Znf_CCCH.
DR   PANTHER; PTHR14738; PTHR14738; 1.
DR   SMART; SM00356; ZnF_C3H1; 3.
DR   PROSITE; PS50103; ZF_C3H1; 3.
PE   2: Evidence at transcript level;
KW   Metal-binding; Nucleus; Reference proteome; Repeat; RNA-binding; Zinc;
KW   Zinc-finger.
FT   CHAIN           1..730
FT                   /note="Zinc finger CCCH domain-containing protein 14"
FT                   /id="PRO_0000331315"
FT   ZN_FING         588..613
FT                   /note="C3H1-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT   ZN_FING         614..633
FT                   /note="C3H1-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT   ZN_FING         634..649
FT                   /note="C3H1-type 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT   ZN_FING         676..693
FT                   /note="C3H1-type 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT   ZN_FING         695..713
FT                   /note="C3H1-type 5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00723"
FT   REGION          76..154
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          269..290
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          307..345
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        76..101
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        117..153
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   730 AA;  81653 MW;  0768F25968B07E6A CRC64;
     MEIGTEISRK IRGAIKGKLQ ELGAYVDEEL PDYIMVMVAN KKSQEQMTED LSLFLGNNTV
     RFTVWLHGVL DKLRSVTTEP SGTKSSEPNI FESNHSSSKS SSCVSDERRR EDTLPPLAVS
     STRSERTDSR VSTSSQEQRN TASRQSCEDG SASRLMSTVK PLRELSPSEA VIDIKPEPDD
     LIDEDLNFVQ ENPLSRKKPI VTVTYGSSRP TAEIYRPPAS RSADGSLQVH RLPQQGNLQG
     NRQLDTQSCR SLETVQLCNP EAFGSLAESY RPTSKLSADK VGSEEEGSRK RRLPIVSSVV
     KVKKFCNDGE EEEEEDDYGL RTGSISSSVS VPAKPERRPS LPPSKQVNKN LILKAISEAQ
     ESVTKTTNYS AVPQKQTVPV APRTRISPEE SHLEVIHLQS RLPALCSQLQ VEEPKEQAVE
     GIQGAEQKEL SSRLQVDPVI EDTLQVTQDY YDGESMVHTD TRSFILKKPK LSEEIAAQNQ
     QLGKRATEAM RVLSGRLIQT RDQIAQPEKP ASPKFIVTLD GVPSPPGYLS DQEEEDMYIT
     EGLKPIPQNI CAGKGLKGLR AQQMQIVTRQ LDSSDVEMEQ LNVLQKQEKV LERCKYWPAC
     KNGDECVYHH PTQPCKVFPN CKFADKCLFI HPNCKYDAKC TKPDCPYTHA SRRNPLPSPK
     PVPLPTQSVS SSSPLCKFFP ACKKMECPFY HPKHCRFNTQ CTRPDCTFYH PTIAVPPRHA
     LKWTRTQTSE