ID   ZCH13_HUMAN             Reviewed;         166 AA.
AC   Q8WW36;
DT   10-MAY-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 139.
DE   RecName: Full=Zinc finger CCHC domain-containing protein 13;
GN   Name=ZCCHC13;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- INTERACTION:
CC       Q8WW36; Q96NT3-2: GUCD1; NbExp=3; IntAct=EBI-954111, EBI-11978177;
CC       Q8WW36; Q8IUQ4: SIAH1; NbExp=3; IntAct=EBI-954111, EBI-747107;
CC       Q8WW36; P09012: SNRPA; NbExp=3; IntAct=EBI-954111, EBI-607085;
CC       Q8WW36; P15622-3: ZNF250; NbExp=3; IntAct=EBI-954111, EBI-10177272;
CC       Q8WW36; Q5T619: ZNF648; NbExp=3; IntAct=EBI-954111, EBI-11985915;
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DR   EMBL; BC021176; AAH21176.1; -; mRNA.
DR   CCDS; CCDS14425.1; -.
DR   RefSeq; NP_976048.1; NM_203303.2.
DR   AlphaFoldDB; Q8WW36; -.
DR   BioGRID; 133309; 6.
DR   IntAct; Q8WW36; 6.
DR   STRING; 9606.ENSP00000345633; -.
DR   iPTMnet; Q8WW36; -.
DR   PhosphoSitePlus; Q8WW36; -.
DR   BioMuta; ZCCHC13; -.
DR   DMDM; 71152962; -.
DR   MassIVE; Q8WW36; -.
DR   PaxDb; Q8WW36; -.
DR   PeptideAtlas; Q8WW36; -.
DR   PRIDE; Q8WW36; -.
DR   Antibodypedia; 28012; 78 antibodies from 16 providers.
DR   DNASU; 389874; -.
DR   Ensembl; ENST00000339534.4; ENSP00000345633.2; ENSG00000187969.6.
DR   GeneID; 389874; -.
DR   KEGG; hsa:389874; -.
DR   MANE-Select; ENST00000339534.4; ENSP00000345633.2; NM_203303.3; NP_976048.1.
DR   UCSC; uc004ebs.5; human.
DR   CTD; 389874; -.
DR   DisGeNET; 389874; -.
DR   GeneCards; ZCCHC13; -.
DR   HGNC; HGNC:31749; ZCCHC13.
DR   HPA; ENSG00000187969; Tissue enriched (testis).
DR   neXtProt; NX_Q8WW36; -.
DR   OpenTargets; ENSG00000187969; -.
DR   PharmGKB; PA134926925; -.
DR   VEuPathDB; HostDB:ENSG00000187969; -.
DR   eggNOG; KOG4400; Eukaryota.
DR   GeneTree; ENSGT00950000183041; -.
DR   HOGENOM; CLU_058879_4_0_1; -.
DR   InParanoid; Q8WW36; -.
DR   OMA; QKEQKCY; -.
DR   OrthoDB; 1535084at2759; -.
DR   PhylomeDB; Q8WW36; -.
DR   TreeFam; TF316974; -.
DR   PathwayCommons; Q8WW36; -.
DR   SignaLink; Q8WW36; -.
DR   BioGRID-ORCS; 389874; 15 hits in 691 CRISPR screens.
DR   GenomeRNAi; 389874; -.
DR   Pharos; Q8WW36; Tdark.
DR   PRO; PR:Q8WW36; -.
DR   Proteomes; UP000005640; Chromosome X.
DR   RNAct; Q8WW36; protein.
DR   Bgee; ENSG00000187969; Expressed in left testis and 12 other tissues.
DR   Genevisible; Q8WW36; HS.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   GO; GO:0003727; F:single-stranded RNA binding; IBA:GO_Central.
DR   GO; GO:0045182; F:translation regulator activity; IBA:GO_Central.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:2000767; P:positive regulation of cytoplasmic translation; IBA:GO_Central.
DR   InterPro; IPR001878; Znf_CCHC.
DR   InterPro; IPR036875; Znf_CCHC_sf.
DR   Pfam; PF00098; zf-CCHC; 4.
DR   SMART; SM00343; ZnF_C2HC; 6.
DR   SUPFAM; SSF57756; SSF57756; 3.
DR   PROSITE; PS50158; ZF_CCHC; 4.
PE   1: Evidence at protein level;
KW   Metal-binding; Reference proteome; Repeat; Zinc; Zinc-finger.
FT   CHAIN           1..166
FT                   /note="Zinc finger CCHC domain-containing protein 13"
FT                   /id="PRO_0000150974"
FT   ZN_FING         4..21
FT                   /note="CCHC-type 1; degenerate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
FT   ZN_FING         45..62
FT                   /note="CCHC-type 2; degenerate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
FT   ZN_FING         65..82
FT                   /note="CCHC-type 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
FT   ZN_FING         89..106
FT                   /note="CCHC-type 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
FT   ZN_FING         110..127
FT                   /note="CCHC-type 5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
FT   ZN_FING         128..145
FT                   /note="CCHC-type 6"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
SQ   SEQUENCE   166 AA;  18005 MW;  40CC28B9FF3F64C3 CRC64;
     MSSKDFFACG HSGHWARGCP RGGAGGRRGG GHGRGSQCGS TTLSYTCYCC GESGRNAKNC
     VLLGNICYNC GRSGHIAKDC KDPKRERRQH CYTCGRLGHL ARDCDRQKEQ KCYSCGKLGH
     IQKDCAQVKC YRCGEIGHVA INCSKARPGQ LLPLRQIPTS SQGMSQ