ZCH24_MOUSE
ID ZCH24_MOUSE Reviewed; 241 AA.
AC B2RVL6;
DT 14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-2008, sequence version 1.
DT 03-AUG-2022, entry version 82.
DE RecName: Full=Zinc finger CCHC domain-containing protein 24 {ECO:0000250|UniProtKB:Q8N2G6};
GN Name=Zcchc24 {ECO:0000250|UniProtKB:Q8N2G6};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1] {ECO:0000312|EMBL:EDL01418.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000312|EMBL:AAI47264.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain {ECO:0000312|EMBL:AAI47264.1};
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Embryonic fibroblast;
RX PubMed=19131326; DOI=10.1074/mcp.m800451-mcp200;
RA Sweet S.M., Bailey C.M., Cunningham D.L., Heath J.K., Cooper H.J.;
RT "Large scale localization of protein phosphorylation by use of electron
RT capture dissociation mass spectrometry.";
RL Mol. Cell. Proteomics 8:904-912(2009).
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DR EMBL; CH466613; EDL01418.1; -; Genomic_DNA.
DR EMBL; BC147263; AAI47264.1; -; mRNA.
DR EMBL; BC147264; AAI47265.1; -; mRNA.
DR CCDS; CCDS49419.1; -.
DR RefSeq; NP_001094903.1; NM_001101433.1.
DR AlphaFoldDB; B2RVL6; -.
DR STRING; 10090.ENSMUSP00000068677; -.
DR iPTMnet; B2RVL6; -.
DR PhosphoSitePlus; B2RVL6; -.
DR jPOST; B2RVL6; -.
DR MaxQB; B2RVL6; -.
DR PaxDb; B2RVL6; -.
DR PeptideAtlas; B2RVL6; -.
DR PRIDE; B2RVL6; -.
DR ProteomicsDB; 275132; -.
DR Antibodypedia; 29874; 126 antibodies from 19 providers.
DR Ensembl; ENSMUST00000069180; ENSMUSP00000068677; ENSMUSG00000055538.
DR GeneID; 71918; -.
DR KEGG; mmu:71918; -.
DR UCSC; uc011zho.1; mouse.
DR CTD; 219654; -.
DR MGI; MGI:1919168; Zcchc24.
DR VEuPathDB; HostDB:ENSMUSG00000055538; -.
DR eggNOG; ENOG502QRVW; Eukaryota.
DR GeneTree; ENSGT00390000008264; -.
DR HOGENOM; CLU_081736_0_0_1; -.
DR InParanoid; B2RVL6; -.
DR OMA; NEPAVGH; -.
DR OrthoDB; 1317500at2759; -.
DR PhylomeDB; B2RVL6; -.
DR TreeFam; TF319664; -.
DR BioGRID-ORCS; 71918; 2 hits in 71 CRISPR screens.
DR ChiTaRS; Zcchc24; mouse.
DR PRO; PR:B2RVL6; -.
DR Proteomes; UP000000589; Chromosome 14.
DR RNAct; B2RVL6; protein.
DR Bgee; ENSMUSG00000055538; Expressed in cerebellar nuclear complex and 215 other tissues.
DR Genevisible; B2RVL6; MM.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR InterPro; IPR033446; Zcchc24_Znf-3CxxC.
DR InterPro; IPR025829; Zn_knuckle_CX2CX3GHX4C.
DR InterPro; IPR027377; Znf-3CxxC.
DR InterPro; IPR001878; Znf_CCHC.
DR InterPro; IPR036875; Znf_CCHC_sf.
DR Pfam; PF17180; zf-3CxxC_2; 1.
DR Pfam; PF13696; zf-CCHC_2; 1.
DR SMART; SM01328; zf-3CxxC; 1.
DR SUPFAM; SSF57756; SSF57756; 1.
DR PROSITE; PS50158; ZF_CCHC; 1.
PE 1: Evidence at protein level;
KW Metal-binding; Phosphoprotein; Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..241
FT /note="Zinc finger CCHC domain-containing protein 24"
FT /id="PRO_0000351149"
FT ZN_FING 132..149
FT /note="CCHC-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
FT MOD_RES 65
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q8N2G6"
FT MOD_RES 93
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q8N2G6"
SQ SEQUENCE 241 AA; 26961 MW; 04B29B3B6A73F306 CRC64;
MSLLSAIDTS AASVYQPAQL LNWVYLSLQD THQASAFDAF RPEPPAGAAP PELAFGKGRP
EQLGSPLHSS YLNSVFQLQR GEALSSSVYR NASPYGSLNN IADGLSSLTE HFSDLTLTSE
ARKPSKRPPP NYLCHLCFNK GHYIKDCPQA RPKGEGLTPY QGKKRCFGEY KCPKCKRKWM
SGNSWANMGQ ECIKCHINVY PHKQRPLEKP DGLDVSDQSK EHPQHLCEKC KVLGYYCRRV
Q