ID   ZCHC7_XENLA             Reviewed;         563 AA.
AC   A1L2T6;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   14-APR-2009, sequence version 2.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=Zinc finger CCHC domain-containing protein 7;
DE   AltName: Full=TRAMP-like complex RNA-binding factor ZCCHC7;
GN   Name=zcchc7;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Thymus;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Component of a nucleolar TRAMP-like complex, an ATP-dependent
CC       exosome regulatory complex consisting of a helicase (MTREX), an
CC       oligadenylate polymerase (PAPD5 or PAPD7), and a substrate specific
CC       RNA-binding factor (ZCCHC7 or ZCCHC8). Several TRAMP-like complexes
CC       exist with specific compositions and are associated with nuclear, or
CC       nucleolar RNA exosomes (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAI29702.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BC129701; AAI29702.1; ALT_INIT; mRNA.
DR   AlphaFoldDB; A1L2T6; -.
DR   PRIDE; A1L2T6; -.
DR   Proteomes; UP000186698; Genome assembly.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   InterPro; IPR001878; Znf_CCHC.
DR   InterPro; IPR036875; Znf_CCHC_sf.
DR   Pfam; PF00098; zf-CCHC; 1.
DR   SMART; SM00343; ZnF_C2HC; 5.
DR   SUPFAM; SSF57756; SSF57756; 2.
DR   PROSITE; PS50158; ZF_CCHC; 3.
PE   2: Evidence at transcript level;
KW   Metal-binding; Nucleus; Reference proteome; Repeat; Zinc; Zinc-finger.
FT   CHAIN           1..563
FT                   /note="Zinc finger CCHC domain-containing protein 7"
FT                   /id="PRO_0000370243"
FT   ZN_FING         265..282
FT                   /note="CCHC-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
FT   ZN_FING         287..304
FT                   /note="CCHC-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
FT   ZN_FING         305..322
FT                   /note="CCHC-type 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
FT   ZN_FING         328..345
FT                   /note="CCHC-type 4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
FT   ZN_FING         372..389
FT                   /note="CCHC-type 5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
FT   REGION          41..64
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          133..157
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          443..494
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   563 AA;  64410 MW;  4D4C83EBFBB177D6 CRC64;
     MFNCDEDLKA YEDELYHEET SSDESIDSEL EFHLYSQVHY SQNLSESKPE EDTGGDSVTY
     VPGAKQQNNA CTEKDDKLVD IIILSDSDAK VSDTCPVIIL SDTTEEDSVY SSKIKKKYSS
     TYVQGESLCG PCSHSTPKVS APQSNNFKSQ KSCQNSSSKN YSGGYVQEVL VIRGSSEDEE
     ANKSENDIII SESDMSDVEN WMLLGRAKED GDASIQLNLE GYKILSDDEG ERGAAWSISE
     KDVEAQIGNY TPLRRSNRYY TDKNVVCRNC DKRGHLSKNC PVPKKLPACC LCGERGHYQN
     SCPSRYCLNC FLPGHFFKEC IERAYWRKTC HRCSMPGHYA DACPEIWRQY HLTIKAGPIK
     KPKSHSGQKD IVYCCNCAKK GHCIYECKER RMNSDKLPTC QLVFSYDHEY DIRKRNERTK
     SKIKDFQKAG LLTCEMREFS ESKVDAKPPA KKRKKKHPSK KERKGTIRDY ECAETKQKKK
     HKKRKSGLQE IEGDFPRGIP NSYVELKKPS KKYDGSFLHL DKTKDMFKNR QKKTRRGKRC
     SSAVDQDLLI IKQKKKKSKR KVA