CC160_HUMAN
ID CC160_HUMAN Reviewed; 325 AA.
AC A6NGH7;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 02-SEP-2008, sequence version 3.
DT 03-AUG-2022, entry version 96.
DE RecName: Full=Coiled-coil domain-containing protein 160;
GN Name=CCDC160;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15772651; DOI=10.1038/nature03440;
RA Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D.,
RA Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L.,
RA Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.,
RA Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A.,
RA Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P.,
RA Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D.,
RA Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D.,
RA Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L.,
RA Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P.,
RA Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G.,
RA Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J.,
RA Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D.,
RA Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L.,
RA Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z.,
RA Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S.,
RA Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S.,
RA Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O.,
RA Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H.,
RA Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T.,
RA Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L.,
RA Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R.,
RA Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y.,
RA Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K.,
RA Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J.,
RA Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L.,
RA Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S.,
RA Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A.,
RA Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L.,
RA Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D.,
RA Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H.,
RA McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S.,
RA Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C.,
RA Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S.,
RA Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V.,
RA Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K.,
RA Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K.,
RA Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D.,
RA Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R.,
RA Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B.,
RA Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C.,
RA d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q.,
RA Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N.,
RA Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A.,
RA Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J.,
RA Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A.,
RA Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F.,
RA Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L.,
RA Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S.,
RA Rogers J., Bentley D.R.;
RT "The DNA sequence of the human X chromosome.";
RL Nature 434:325-337(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the CCDC160 family. {ECO:0000305}.
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DR EMBL; AC004409; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH471107; EAX11768.1; -; Genomic_DNA.
DR CCDS; CCDS48171.1; -.
DR RefSeq; NP_001094827.1; NM_001101357.1.
DR RefSeq; XP_005262466.1; XM_005262409.4.
DR RefSeq; XP_005262467.1; XM_005262410.4.
DR AlphaFoldDB; A6NGH7; -.
DR SMR; A6NGH7; -.
DR BioGRID; 131441; 1.
DR IntAct; A6NGH7; 1.
DR MINT; A6NGH7; -.
DR STRING; 9606.ENSP00000427951; -.
DR iPTMnet; A6NGH7; -.
DR PhosphoSitePlus; A6NGH7; -.
DR BioMuta; CCDC160; -.
DR MassIVE; A6NGH7; -.
DR MaxQB; A6NGH7; -.
DR PaxDb; A6NGH7; -.
DR PeptideAtlas; A6NGH7; -.
DR PRIDE; A6NGH7; -.
DR ProteomicsDB; 1127; -.
DR Antibodypedia; 50575; 9 antibodies from 5 providers.
DR DNASU; 347475; -.
DR Ensembl; ENST00000370809.4; ENSP00000359845.4; ENSG00000203952.9.
DR Ensembl; ENST00000517294.5; ENSP00000427951.1; ENSG00000203952.9.
DR GeneID; 347475; -.
DR KEGG; hsa:347475; -.
DR UCSC; uc011mvj.2; human.
DR CTD; 347475; -.
DR GeneCards; CCDC160; -.
DR HGNC; HGNC:37286; CCDC160.
DR HPA; ENSG00000203952; Tissue enhanced (salivary).
DR neXtProt; NX_A6NGH7; -.
DR OpenTargets; ENSG00000203952; -.
DR PharmGKB; PA165756450; -.
DR VEuPathDB; HostDB:ENSG00000203952; -.
DR eggNOG; ENOG502RVAM; Eukaryota.
DR GeneTree; ENSGT00390000013938; -.
DR HOGENOM; CLU_058746_0_0_1; -.
DR InParanoid; A6NGH7; -.
DR OMA; CIWNAKE; -.
DR OrthoDB; 1366530at2759; -.
DR PhylomeDB; A6NGH7; -.
DR TreeFam; TF351883; -.
DR PathwayCommons; A6NGH7; -.
DR SignaLink; A6NGH7; -.
DR BioGRID-ORCS; 347475; 15 hits in 689 CRISPR screens.
DR ChiTaRS; CCDC160; human.
DR GenomeRNAi; 347475; -.
DR Pharos; A6NGH7; Tdark.
DR PRO; PR:A6NGH7; -.
DR Proteomes; UP000005640; Chromosome X.
DR RNAct; A6NGH7; protein.
DR Bgee; ENSG00000203952; Expressed in oviduct epithelium and 94 other tissues.
DR Genevisible; A6NGH7; HS.
DR InterPro; IPR026789; Ccdc160.
DR PANTHER; PTHR11636:SF71; PTHR11636:SF71; 1.
PE 3: Inferred from homology;
KW Coiled coil; Reference proteome.
FT CHAIN 1..325
FT /note="Coiled-coil domain-containing protein 160"
FT /id="PRO_0000345951"
FT REGION 18..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 81..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 144..288
FT /evidence="ECO:0000255"
FT COMPBIAS 20..45
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 89..123
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 325 AA; 38277 MW; 63E95ACBF5A6910C CRC64;
MDARRKHWKE NMFTPFFSAQ DVLEETSEPE SSSEQTTADS SKGMEEIYNL SSRKFQEESK
FKRKKYIFQL NEIEQEQNLR ENKRNISKNE TDTNSASYES SNVDVTTEES FNSTEDNSTC
STDNLPALLR QDIRKKFMER MSPKLCLNLL NEELEELNMK YRKIEEEFEN AEKELLHYKK
EIFTKPLNFQ ETETDASKSD YELQALRNDL SEKATNVKNL SEQLQQAKEV IHKLNLENRN
LKEAVRKLKH QTEVGNVLLK EEMKSYYELE MAKIRGELSV IKNELRTEKT LQARNNRALE
LLRKYYASSM VTSSSILDHF TGDFF
