CC160_MOUSE
ID CC160_MOUSE Reviewed; 323 AA.
AC Q3UYG1;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2005, sequence version 1.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=Coiled-coil domain-containing protein 160;
GN Name=Ccdc160;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Medulla oblongata;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the CCDC160 family. {ECO:0000305}.
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DR EMBL; AK134708; BAE22251.1; -; mRNA.
DR EMBL; CH466570; EDL29116.1; -; Genomic_DNA.
DR EMBL; BX936351; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC138946; AAI38947.1; -; mRNA.
DR EMBL; BC138947; AAI38948.1; -; mRNA.
DR CCDS; CCDS30126.1; -.
DR RefSeq; NP_001029231.1; NM_001034059.1.
DR RefSeq; XP_006541574.1; XM_006541511.1.
DR AlphaFoldDB; Q3UYG1; -.
DR SMR; Q3UYG1; -.
DR STRING; 10090.ENSMUSP00000099121; -.
DR iPTMnet; Q3UYG1; -.
DR PhosphoSitePlus; Q3UYG1; -.
DR MaxQB; Q3UYG1; -.
DR PaxDb; Q3UYG1; -.
DR PeptideAtlas; Q3UYG1; -.
DR PRIDE; Q3UYG1; -.
DR ProteomicsDB; 265698; -.
DR Antibodypedia; 50575; 9 antibodies from 5 providers.
DR Ensembl; ENSMUST00000101588; ENSMUSP00000099121; ENSMUSG00000073207.
DR GeneID; 434778; -.
DR KEGG; mmu:434778; -.
DR UCSC; uc009tem.1; mouse.
DR CTD; 347475; -.
DR MGI; MGI:3588225; Ccdc160.
DR VEuPathDB; HostDB:ENSMUSG00000073207; -.
DR eggNOG; ENOG502RVAM; Eukaryota.
DR GeneTree; ENSGT00390000013938; -.
DR HOGENOM; CLU_058746_0_0_1; -.
DR InParanoid; Q3UYG1; -.
DR OMA; CIWNAKE; -.
DR OrthoDB; 1366530at2759; -.
DR PhylomeDB; Q3UYG1; -.
DR TreeFam; TF351883; -.
DR BioGRID-ORCS; 434778; 3 hits in 73 CRISPR screens.
DR ChiTaRS; Ccdc160; mouse.
DR PRO; PR:Q3UYG1; -.
DR Proteomes; UP000000589; Chromosome X.
DR RNAct; Q3UYG1; protein.
DR Bgee; ENSMUSG00000073207; Expressed in facial nucleus and 155 other tissues.
DR Genevisible; Q3UYG1; MM.
DR InterPro; IPR026789; Ccdc160.
DR PANTHER; PTHR11636:SF71; PTHR11636:SF71; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Reference proteome.
FT CHAIN 1..323
FT /note="Coiled-coil domain-containing protein 160"
FT /id="PRO_0000345952"
FT REGION 1..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 144..289
FT /evidence="ECO:0000255"
FT COMPBIAS 29..56
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..81
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 323 AA; 37398 MW; BCB10A5BBC712E40 CRC64;
MDARRKHWKD NTFTPFLNEH DFQEAAAPPQ PLSEQSSADN HKRMGRVSNF SVRNTQEGNK
FKRKDYSSQI AEGEQDSNLR ERRMNVSKND ANTNSAFWDS LHLDDATKES SHRRESASAW
NKKKLPAATQ VTRKKWTEAM PPKLRLHLLN EELGELSLKC REIERDFENA EKELLNFRKE
ASVKAVNFQE PGTGASKKDR ELQALKNDLS EKATNVKNLT EELQQAKEVM YRLSLENRNL
KDAVRKLKHQ TELNTALLRE EMKLFYELEM EKIRLELGAI KNELRVEKTL RVKNSRALEV
LGRHVASVVR SSNPADHFTG NIF
