ID   ZCRB1_BOVIN             Reviewed;         217 AA.
AC   Q56JZ7; Q32KW1;
DT   17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=Zinc finger CCHC-type and RNA-binding motif-containing protein 1;
DE   AltName: Full=U11/U12 small nuclear ribonucleoprotein 31 kDa protein;
DE            Short=U11/U12 snRNP 31 kDa protein;
GN   Name=ZCRB1;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Lymphoid epithelium;
RA   Yu J., Meng Y., Wang Z., Hansen C., Li C., Moore S.S.;
RT   "Analysis of sequences obtained from constructed full-length bovine cDNA
RT   libraries.";
RL   Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-139.
RC   TISSUE=Lymphoid tissue;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Component of the U11/U12 snRNPs that are part of the U12-type
CC       spliceosome. Interacts with ZRSR1 (By similarity). {ECO:0000250,
CC       ECO:0000250|UniProtKB:Q9CZ96}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleoplasm {ECO:0000250}.
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DR   EMBL; AY911330; AAW82098.1; -; mRNA.
DR   EMBL; BC109899; AAI09900.1; -; mRNA.
DR   RefSeq; NP_001020489.1; NM_001025318.2.
DR   AlphaFoldDB; Q56JZ7; -.
DR   SMR; Q56JZ7; -.
DR   STRING; 9913.ENSBTAP00000025452; -.
DR   PaxDb; Q56JZ7; -.
DR   PRIDE; Q56JZ7; -.
DR   Ensembl; ENSBTAT00000025452; ENSBTAP00000025452; ENSBTAG00000019119.
DR   GeneID; 504536; -.
DR   KEGG; bta:504536; -.
DR   CTD; 85437; -.
DR   VEuPathDB; HostDB:ENSBTAG00000019119; -.
DR   VGNC; VGNC:37124; ZCRB1.
DR   eggNOG; KOG0118; Eukaryota.
DR   GeneTree; ENSGT00730000111061; -.
DR   HOGENOM; CLU_059455_1_0_1; -.
DR   InParanoid; Q56JZ7; -.
DR   OMA; RXVTIMK; -.
DR   OrthoDB; 1422822at2759; -.
DR   TreeFam; TF106263; -.
DR   Proteomes; UP000009136; Chromosome 5.
DR   Bgee; ENSBTAG00000019119; Expressed in myometrium and 107 other tissues.
DR   ExpressionAtlas; Q56JZ7; baseline.
DR   GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005689; C:U12-type spliceosomal complex; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR   CDD; cd12393; RRM_ZCRB1; 1.
DR   Gene3D; 3.30.70.330; -; 1.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   InterPro; IPR003954; RRM_dom_euk.
DR   InterPro; IPR044598; ZCRB1.
DR   InterPro; IPR034219; ZCRB1_RRM.
DR   InterPro; IPR001878; Znf_CCHC.
DR   InterPro; IPR036875; Znf_CCHC_sf.
DR   PANTHER; PTHR46259; PTHR46259; 1.
DR   Pfam; PF00076; RRM_1; 1.
DR   Pfam; PF00098; zf-CCHC; 1.
DR   SMART; SM00360; RRM; 1.
DR   SMART; SM00361; RRM_1; 1.
DR   SMART; SM00343; ZnF_C2HC; 1.
DR   SUPFAM; SSF54928; SSF54928; 1.
DR   SUPFAM; SSF57756; SSF57756; 1.
DR   PROSITE; PS50102; RRM; 1.
DR   PROSITE; PS50158; ZF_CCHC; 1.
PE   2: Evidence at transcript level;
KW   Metal-binding; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein;
KW   Reference proteome; RNA-binding; Spliceosome; Zinc; Zinc-finger.
FT   CHAIN           1..217
FT                   /note="Zinc finger CCHC-type and RNA-binding motif-
FT                   containing protein 1"
FT                   /id="PRO_0000252372"
FT   DOMAIN          10..88
FT                   /note="RRM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   ZN_FING         105..122
FT                   /note="CCHC-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
FT   REGION          120..217
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        147..163
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        197..217
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         155
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8TBF4"
FT   MOD_RES         210
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8TBF4"
FT   MOD_RES         216
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8TBF4"
SQ   SEQUENCE   217 AA;  24620 MW;  DC165F473D2130A9 CRC64;
     MSGGLAPSKS TVYVSNLPFS LTNNDLYRIF SKYGKVVKVT IMKDKDTRRS KGVAFILFLD
     KDSAQNCTRA INNKQLFGRV IKASIAIDNG RAAEFIRRRN YFDKSKCYEC GESGHLSYAC
     PKNMLGEREP PKKKEKKKKK KIPEPEEEIE EVEESEDEGE DPALDSLSQA IAFQQAKIEE
     EQKKWKPSSG GPSTSDDSRR PRIKKSTYFS DEEELSD