ZCRB1_XENLA
ID ZCRB1_XENLA Reviewed; 218 AA.
AC Q6DJI9;
DT 17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 03-AUG-2022, entry version 87.
DE RecName: Full=Zinc finger CCHC-type and RNA-binding motif-containing protein 1;
DE AltName: Full=U11/U12 small nuclear ribonucleoprotein 31 kDa protein;
DE Short=U11/U12 snRNP 31 kDa protein;
GN Name=zcrb1;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Kidney;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Component of the U11/U12 snRNPs that are part of the U12-type
CC spliceosome. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR EMBL; BC075189; AAH75189.1; -; mRNA.
DR RefSeq; NP_001086476.1; NM_001093007.1.
DR AlphaFoldDB; Q6DJI9; -.
DR SMR; Q6DJI9; -.
DR MaxQB; Q6DJI9; -.
DR DNASU; 446310; -.
DR GeneID; 446310; -.
DR KEGG; xla:446310; -.
DR CTD; 446310; -.
DR Xenbase; XB-GENE-6251504; zcrb1.L.
DR OMA; RXVTIMK; -.
DR OrthoDB; 1422822at2759; -.
DR Proteomes; UP000186698; Chromosome 3L.
DR Bgee; 446310; Expressed in gastrula and 19 other tissues.
DR GO; GO:0005689; C:U12-type spliceosomal complex; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR CDD; cd12393; RRM_ZCRB1; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR003954; RRM_dom_euk.
DR InterPro; IPR044598; ZCRB1.
DR InterPro; IPR034219; ZCRB1_RRM.
DR InterPro; IPR001878; Znf_CCHC.
DR InterPro; IPR036875; Znf_CCHC_sf.
DR PANTHER; PTHR46259; PTHR46259; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF00098; zf-CCHC; 1.
DR SMART; SM00360; RRM; 1.
DR SMART; SM00361; RRM_1; 1.
DR SMART; SM00343; ZnF_C2HC; 1.
DR SUPFAM; SSF54928; SSF54928; 1.
DR SUPFAM; SSF57756; SSF57756; 1.
DR PROSITE; PS50102; RRM; 1.
DR PROSITE; PS50158; ZF_CCHC; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Metal-binding; mRNA processing; mRNA splicing; Nucleus;
KW Reference proteome; RNA-binding; Spliceosome; Zinc; Zinc-finger.
FT CHAIN 1..218
FT /note="Zinc finger CCHC-type and RNA-binding motif-
FT containing protein 1"
FT /id="PRO_0000252377"
FT DOMAIN 10..88
FT /note="RRM"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT ZN_FING 105..122
FT /note="CCHC-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
FT REGION 119..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 132..188
FT /evidence="ECO:0000255"
FT COMPBIAS 127..146
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 147..164
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 178..218
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 218 AA; 24881 MW; 4AF57EDBD6D8C946 CRC64;
MSGGLAPSKS TVYVSNLPFS LTNNDLHRIF SKYGKVVKVT ILKDKDSRKS KGVSFVLFLD
KESAQNCVRG LNNKQLFGRA IKASIAKDNG RATEFIRRRN YTDKSRCYEC GDTGHLSYAC
PKNMLGEREP PQKKEKKKRK RLVEEEEEEV VEEEESEDEG EDPALDSLSQ AIAFQQARID
EEKNKYRHDP AEASTSEDSR RPRIKKSTYF SDEDELSD
