CC163_HUMAN
ID CC163_HUMAN Reviewed; 145 AA.
AC A0A0D9SF12;
DT 20-JUN-2018, integrated into UniProtKB/Swiss-Prot.
DT 27-MAY-2015, sequence version 1.
DT 03-AUG-2022, entry version 36.
DE RecName: Full=Transmembrane protein CCDC163 {ECO:0000305};
DE AltName: Full=Coiled-coil domain-containing protein 163 {ECO:0000305};
DE AltName: Full=coiled-coil domain containing 163 pseudogene {ECO:0000312|HGNC:HGNC:27003};
GN Name=CCDC163 {ECO:0000312|HGNC:HGNC:27003};
GN Synonyms=C1orf231 {ECO:0000312|HGNC:HGNC:27003},
GN CCDC163P {ECO:0000312|HGNC:HGNC:27003};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16710414; DOI=10.1038/nature04727;
RA Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A.,
RA Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C.,
RA Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.,
RA Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C.,
RA Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W.,
RA Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J.,
RA Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J.,
RA Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y.,
RA Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J.,
RA Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S.,
RA Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K.,
RA Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R.,
RA Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M.,
RA Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S.,
RA Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J.,
RA Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W.,
RA McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N.,
RA Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V.,
RA Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J.,
RA Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E.,
RA Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S.,
RA Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M.,
RA White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H.,
RA Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E.,
RA Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G.,
RA Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.;
RT "The DNA sequence and biological annotation of human chromosome 1.";
RL Nature 441:315-321(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Single-pass membrane
CC protein {ECO:0000255}.
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DR EMBL; AL451136; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC101255; -; NOT_ANNOTATED_CDS; mRNA.
DR AlphaFoldDB; A0A0D9SF12; -.
DR SMR; A0A0D9SF12; -.
DR PhosphoSitePlus; A0A0D9SF12; -.
DR BioMuta; CCDC163; -.
DR MassIVE; A0A0D9SF12; -.
DR PaxDb; A0A0D9SF12; -.
DR PeptideAtlas; A0A0D9SF12; -.
DR Ensembl; ENST00000629482.3; ENSP00000486197.1; ENSG00000280670.3.
DR MANE-Select; ENST00000629482.3; ENSP00000486197.1; NM_001102601.3; NP_001096071.1.
DR GeneCards; CCDC163; -.
DR HGNC; HGNC:27003; CCDC163.
DR HPA; ENSG00000280670; Not detected.
DR neXtProt; NX_A0A0D9SF12; -.
DR OpenTargets; ENSG00000280670; -.
DR VEuPathDB; HostDB:ENSG00000280670; -.
DR GeneTree; ENSGT00940000165040; -.
DR OMA; IDLCNCF; -.
DR ChiTaRS; CCDC163; human.
DR Pharos; A0A0D9SF12; Tdark.
DR PRO; PR:A0A0D9SF12; -.
DR Proteomes; UP000005640; Chromosome 1.
DR RNAct; A0A0D9SF12; protein.
DR Bgee; ENSG00000280670; Expressed in oocyte and 102 other tissues.
DR ExpressionAtlas; A0A0D9SF12; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR039284; CCDC159/163.
DR PANTHER; PTHR34533; PTHR34533; 2.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..145
FT /note="Transmembrane protein CCDC163"
FT /id="PRO_0000444575"
FT TRANSMEM 38..54
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 145 AA; 16203 MW; 9BDA0DC861063867 CRC64;
MNTSLSWFEQ LDVLLNATDG NVVRNKQWLY PLGVSTELIG LCICFFCSSG CIFLGSPPQN
STAVTPAVLW EESEIMQKEL KLLQYQLSQH QELLLKQLAE GRQAQVGSWK IPRGAPFLTW
SPASFSSMPR VLSKRTYSFG APKCS
