ID   CC167_DANRE             Reviewed;         100 AA.
AC   Q5RHZ2; A3KNS5; B0S617;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Coiled-coil domain-containing protein 167;
GN   Name=ccdc167; ORFNames=si:ch211-214j24.7;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen;
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA   Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA   Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA   White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA   Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA   Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA   Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA   Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA   Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA   Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA   Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA   McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA   Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA   Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA   Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA   Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA   Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA   Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA   Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA   Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA   Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA   Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA   de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA   Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the human
RT   genome.";
RL   Nature 496:498-503(2013).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC   TISSUE=Embryo;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q5RHZ2-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q5RHZ2-2; Sequence=VSP_034840;
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DR   EMBL; BX323558; CAI11786.2; -; Genomic_DNA.
DR   EMBL; BX323558; CAQ14315.1; -; Genomic_DNA.
DR   EMBL; BC133988; AAI33989.1; -; mRNA.
DR   RefSeq; NP_001315525.1; NM_001328596.1. [Q5RHZ2-1]
DR   AlphaFoldDB; Q5RHZ2; -.
DR   SMR; Q5RHZ2; -.
DR   STRING; 7955.ENSDARP00000067379; -.
DR   PaxDb; Q5RHZ2; -.
DR   Ensembl; ENSDART00000137966; ENSDARP00000118096; ENSDARG00000045850. [Q5RHZ2-1]
DR   Ensembl; ENSDART00000144658; ENSDARP00000117654; ENSDARG00000045850. [Q5RHZ2-1]
DR   GeneID; 556080; -.
DR   KEGG; dre:556080; -.
DR   CTD; 154467; -.
DR   ZFIN; ZDB-GENE-041210-79; ccdc167.
DR   eggNOG; ENOG502SAF4; Eukaryota.
DR   GeneTree; ENSGT00390000010210; -.
DR   HOGENOM; CLU_152032_0_0_1; -.
DR   InParanoid; Q5RHZ2; -.
DR   OMA; IYACWTM; -.
DR   OrthoDB; 1588154at2759; -.
DR   PhylomeDB; Q5RHZ2; -.
DR   TreeFam; TF336097; -.
DR   PRO; PR:Q5RHZ2; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 4.
DR   Bgee; ENSDARG00000045850; Expressed in granulocyte and 29 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR028194; CCDC-167.
DR   PANTHER; PTHR31759; PTHR31759; 1.
DR   Pfam; PF15188; CCDC-167; 1.
PE   4: Predicted;
KW   Alternative splicing; Coiled coil; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..100
FT                   /note="Coiled-coil domain-containing protein 167"
FT                   /id="PRO_0000308552"
FT   TRANSMEM        82..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   COILED          14..81
FT                   /evidence="ECO:0000255"
FT   VAR_SEQ         67..100
FT                   /note="EKDLQVLRGENRRNMMLSVALLAISALFYYTFIY -> GIYGPRLTPSRFPS
FT                   TF (in isoform 2)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_034840"
FT   CONFLICT        10
FT                   /note="E -> G (in Ref. 2; AAI33989)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   100 AA;  12007 MW;  840AD19257FE9A93 CRC64;
     MTRTRTVKKE KISVASEIDR VEERKLQCKN SLERAEFRKR KQQLSDDDRL ALEDEMTILN
     ERVEKYEKDL QVLRGENRRN MMLSVALLAI SALFYYTFIY