ID   ZDH1_STAAN              Reviewed;         335 AA.
AC   P99173; Q99S81;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=Zinc-type alcohol dehydrogenase-like protein SA1988;
GN   OrderedLocusNames=SA1988;
OS   Staphylococcus aureus (strain N315).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=158879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=N315;
RX   PubMed=11418146; DOI=10.1016/s0140-6736(00)04403-2;
RA   Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L.,
RA   Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M.,
RA   Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y.,
RA   Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H.,
RA   Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K.,
RA   Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H.,
RA   Hiramatsu K.;
RT   "Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
RL   Lancet 357:1225-1240(2001).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RC   STRAIN=N315;
RX   PubMed=15590099; DOI=10.1016/j.mimet.2004.09.017;
RA   Scherl A., Francois P., Bento M., Deshusses J.M., Charbonnier Y.,
RA   Converset V., Huyghe A., Walter N., Hoogland C., Appel R.D., Sanchez J.-C.,
RA   Zimmermann-Ivol C.G., Corthals G.L., Hochstrasser D.F., Schrenzel J.;
RT   "Correlation of proteomic and transcriptomic profiles of Staphylococcus
RT   aureus during the post-exponential phase of growth.";
RL   J. Microbiol. Methods 60:247-257(2005).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=N315;
RA   Vaezzadeh A.R., Deshusses J., Lescuyer P., Hochstrasser D.F.;
RT   "Shotgun proteomic analysis of total and membrane protein extracts of S.
RT   aureus strain N315.";
RL   Submitted (OCT-2007) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. Quinone oxidoreductase subfamily. {ECO:0000305}.
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DR   EMBL; BA000018; BAB43278.1; -; Genomic_DNA.
DR   PIR; E90014; E90014.
DR   RefSeq; WP_000781951.1; NC_002745.2.
DR   AlphaFoldDB; P99173; -.
DR   SMR; P99173; -.
DR   SWISS-2DPAGE; P99173; -.
DR   EnsemblBacteria; BAB43278; BAB43278; BAB43278.
DR   KEGG; sau:SA1988; -.
DR   HOGENOM; CLU_026673_3_0_9; -.
DR   OMA; QGTYSEY; -.
DR   Proteomes; UP000000751; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd08252; AL_MDR; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH_N.
DR   InterPro; IPR014182; ADH_Zn_typ-1.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   InterPro; IPR002364; Quin_OxRdtase/zeta-crystal_CS.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; SSF50129; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   TIGRFAMs; TIGR02817; adh_fam_1; 1.
DR   PROSITE; PS01162; QOR_ZETA_CRYSTAL; 1.
PE   1: Evidence at protein level;
KW   Metal-binding; Oxidoreductase; Zinc.
FT   CHAIN           1..335
FT                   /note="Zinc-type alcohol dehydrogenase-like protein SA1988"
FT                   /id="PRO_0000160928"
SQ   SEQUENCE   335 AA;  37574 MW;  10C87330ADC4C612 CRC64;
     MKMIGFEKPF KLEEGNLFKV YEQRKPTPEN DDILVKVNSI SVNPVDTKQR QMKVTQAPRV
     LGFDAIGTVE AIGPDVTLFS PGDVVFYAGS PNRQGSNATY QLVSEAIVAK APHNISANEA
     VSLPLTGITA YETFFDTFKI SHNPSENVGK SVLIINGAGG VGSIATQIAK RYGLTVITTA
     SRQETTEWCE KMGADIVLNH KEDLVRQFKE KEIPLVDYIF CTYNTDLYYN TMIELIKPLG
     HITTIVAFNE DQDLNALKLK SITFTHEFMF ARPIHRTPDM IKQHEYLEDI TKNIELGHYQ
     PTTTQVFEGL SPENLYQAHQ LLEKQSMIGK LVINI