ID   ZDH1_STAAR              Reviewed;         335 AA.
AC   Q6GEP3;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=Zinc-type alcohol dehydrogenase-like protein SAR2277;
GN   OrderedLocusNames=SAR2277;
OS   Staphylococcus aureus (strain MRSA252).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=282458;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MRSA252;
RX   PubMed=15213324; DOI=10.1073/pnas.0402521101;
RA   Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J.,
RA   Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A.,
RA   Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C.,
RA   Clark L., Corton C., Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z.,
RA   Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N.,
RA   Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A.,
RA   Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M.,
RA   Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J.;
RT   "Complete genomes of two clinical Staphylococcus aureus strains: evidence
RT   for the rapid evolution of virulence and drug resistance.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004).
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. Quinone oxidoreductase subfamily. {ECO:0000305}.
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DR   EMBL; BX571856; CAG41255.1; -; Genomic_DNA.
DR   RefSeq; WP_000781946.1; NC_002952.2.
DR   AlphaFoldDB; Q6GEP3; -.
DR   SMR; Q6GEP3; -.
DR   KEGG; sar:SAR2277; -.
DR   HOGENOM; CLU_026673_3_0_9; -.
DR   OMA; QGTYSEY; -.
DR   OrthoDB; 1752728at2; -.
DR   Proteomes; UP000000596; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd08252; AL_MDR; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH_N.
DR   InterPro; IPR014182; ADH_Zn_typ-1.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   InterPro; IPR002364; Quin_OxRdtase/zeta-crystal_CS.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; SSF50129; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   TIGRFAMs; TIGR02817; adh_fam_1; 1.
DR   PROSITE; PS01162; QOR_ZETA_CRYSTAL; 1.
PE   3: Inferred from homology;
KW   Metal-binding; Oxidoreductase; Zinc.
FT   CHAIN           1..335
FT                   /note="Zinc-type alcohol dehydrogenase-like protein
FT                   SAR2277"
FT                   /id="PRO_0000160929"
SQ   SEQUENCE   335 AA;  37547 MW;  5AF39120799222C4 CRC64;
     MKMIGFEKPF KLEEGNLFKV YEQRKPTPEN DDILVKVNSI SVNPVDTKQR QMEVTQAPRV
     LGFDAIGTVE AIGPNVTLFS PGDVVFYAGS PNRQGSNATY QLVSEAIVAK APHNISANEA
     VSLPLTGITA YETFFDTFKI SHNPSENIGK SVLIINGAGG VGSIATQIAK RYGLTVITTA
     SRQETTEWCE KMGADIVLNH KEDLVRQFKE KEIPLVDYIF CTYNTDLYYN TMIELIKPLG
     HITTIVAFNE DQDLNALKLK SITFTHEFMF ARPIHRTPDM IKQHEYLEDI TKNIESGHYQ
     PTTTQVFEGL SPENLYQAHL LLEKQSMIGK LVINI