ID   ZDH1_STAAS              Reviewed;         335 AA.
AC   Q6G7C8;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=Zinc-type alcohol dehydrogenase-like protein SAS2087;
GN   OrderedLocusNames=SAS2087;
OS   Staphylococcus aureus (strain MSSA476).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=282459;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MSSA476;
RX   PubMed=15213324; DOI=10.1073/pnas.0402521101;
RA   Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J.,
RA   Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A.,
RA   Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C.,
RA   Clark L., Corton C., Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z.,
RA   Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N.,
RA   Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A.,
RA   Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M.,
RA   Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J.;
RT   "Complete genomes of two clinical Staphylococcus aureus strains: evidence
RT   for the rapid evolution of virulence and drug resistance.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004).
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. Quinone oxidoreductase subfamily. {ECO:0000305}.
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DR   EMBL; BX571857; CAG43895.1; -; Genomic_DNA.
DR   RefSeq; WP_000781934.1; NC_002953.3.
DR   AlphaFoldDB; Q6G7C8; -.
DR   SMR; Q6G7C8; -.
DR   KEGG; sas:SAS2087; -.
DR   HOGENOM; CLU_026673_3_0_9; -.
DR   OMA; QGTYSEY; -.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd08252; AL_MDR; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH_N.
DR   InterPro; IPR014182; ADH_Zn_typ-1.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   InterPro; IPR002364; Quin_OxRdtase/zeta-crystal_CS.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; SSF50129; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   TIGRFAMs; TIGR02817; adh_fam_1; 1.
DR   PROSITE; PS01162; QOR_ZETA_CRYSTAL; 1.
PE   3: Inferred from homology;
KW   Metal-binding; Oxidoreductase; Zinc.
FT   CHAIN           1..335
FT                   /note="Zinc-type alcohol dehydrogenase-like protein
FT                   SAS2087"
FT                   /id="PRO_0000160930"
SQ   SEQUENCE   335 AA;  37563 MW;  0CE02EC5560063EB CRC64;
     MKMIGFEKPF KLEEGNLFKV YEQRKPTPEN DDILVKVNSI SVNPVDTKQR QMEVTQAPRV
     LGFDAIGTVE AIGPDVTLFS PGDVVFYAGS PNRQGSNATY QLVSEAIVAK APHNISANEA
     VSLPLTGITA YETFFDTFKI SHNPAENEGK SVLIINGAGG VGSIATQIAK RYGLTVITTA
     SRQETTEWCE KMGADIVLNH KEDLVRQFKE KEIPLVDYIF CTYNTDLYYN TMIELIKPLG
     HITTIVAFNE DQDLNALKLK SITFTHEFMF ARPIHRTPDM IKQHEYLEDI TKNIESGHYQ
     PTTTQVFEGL SPENLYQAHQ LLEKQSMIGK LVINI