CC169_MOUSE
ID CC169_MOUSE Reviewed; 214 AA.
AC Q8BXX9; Q8BVQ6;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 04-NOV-2008, sequence version 2.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=Coiled-coil domain-containing protein 169;
GN Name=Ccdc169;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=C57BL/6J; TISSUE=Cerebellum, and Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q8BXX9-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q8BXX9-2; Sequence=VSP_035638;
CC -!- SIMILARITY: Belongs to the CCDC169 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AK042903; BAC31401.1; -; mRNA.
DR EMBL; AK076919; BAC36528.2; -; mRNA.
DR EMBL; AK160422; BAE35780.1; -; mRNA.
DR CCDS; CCDS17357.2; -. [Q8BXX9-1]
DR CCDS; CCDS79907.1; -. [Q8BXX9-2]
DR RefSeq; NP_001277067.1; NM_001290138.1. [Q8BXX9-2]
DR RefSeq; NP_001277070.1; NM_001290141.1. [Q8BXX9-2]
DR RefSeq; NP_796177.2; NM_177203.3. [Q8BXX9-1]
DR RefSeq; XP_006501638.1; XM_006501575.2. [Q8BXX9-2]
DR RefSeq; XP_017175102.1; XM_017319613.1. [Q8BXX9-2]
DR RefSeq; XP_017175103.1; XM_017319614.1. [Q8BXX9-2]
DR AlphaFoldDB; Q8BXX9; -.
DR SMR; Q8BXX9; -.
DR STRING; 10090.ENSMUSP00000054771; -.
DR iPTMnet; Q8BXX9; -.
DR PhosphoSitePlus; Q8BXX9; -.
DR PaxDb; Q8BXX9; -.
DR PRIDE; Q8BXX9; -.
DR ProteomicsDB; 283713; -. [Q8BXX9-1]
DR ProteomicsDB; 283714; -. [Q8BXX9-2]
DR Antibodypedia; 52943; 15 antibodies from 3 providers.
DR Ensembl; ENSMUST00000052904; ENSMUSP00000049698; ENSMUSG00000048655. [Q8BXX9-2]
DR Ensembl; ENSMUST00000061099; ENSMUSP00000054771; ENSMUSG00000048655. [Q8BXX9-1]
DR GeneID; 320604; -.
DR KEGG; mmu:320604; -.
DR UCSC; uc008pgg.3; mouse. [Q8BXX9-1]
DR UCSC; uc012cpo.2; mouse. [Q8BXX9-2]
DR CTD; 728591; -.
DR MGI; MGI:2444356; Ccdc169.
DR VEuPathDB; HostDB:ENSMUSG00000048655; -.
DR eggNOG; ENOG502S1I0; Eukaryota.
DR GeneTree; ENSGT00390000011174; -.
DR HOGENOM; CLU_158060_0_0_1; -.
DR InParanoid; Q8BXX9; -.
DR OMA; YERMSVE; -.
DR OrthoDB; 1431259at2759; -.
DR PhylomeDB; Q8BXX9; -.
DR TreeFam; TF329642; -.
DR BioGRID-ORCS; 320604; 5 hits in 67 CRISPR screens.
DR PRO; PR:Q8BXX9; -.
DR Proteomes; UP000000589; Chromosome 3.
DR RNAct; Q8BXX9; protein.
DR Bgee; ENSMUSG00000048655; Expressed in spermatid and 19 other tissues.
DR ExpressionAtlas; Q8BXX9; baseline and differential.
DR Genevisible; Q8BXX9; MM.
DR InterPro; IPR028022; DUF4600.
DR PANTHER; PTHR28671; PTHR28671; 1.
DR Pfam; PF15372; DUF4600; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Coiled coil; Reference proteome.
FT CHAIN 1..214
FT /note="Coiled-coil domain-containing protein 169"
FT /id="PRO_0000341367"
FT REGION 154..214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 56..138
FT /evidence="ECO:0000255"
FT COMPBIAS 154..168
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 182..196
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..82
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_035638"
SQ SEQUENCE 214 AA; 24754 MW; B33D5D9BC457F054 CRC64;
MGEGHGDTFE GVSTDRLKLE LLEEIHMKDV VQLSTLEIRH KIAELEANLN GDLAGSEWKT
RYETQLELND QLEKQIVSLK EKMEKMRGNP SDRLSSIRVY EKMPVESLNV LLKQLEKEKR
SLESQVKEYA FRLEQESKAY HRTNNERRSY IAEMTQVSGS NQVSKRQQMD PLPRMKESPV
KTGRHNSMNQ KTTNAKKGPV KKVPRSNHLP KLNP
