ID   ZDS_MAIZE               Reviewed;         570 AA.
AC   Q9ZTP4;
DT   02-NOV-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=Zeta-carotene desaturase, chloroplastic/chromoplastic;
DE            EC=1.3.5.6;
DE   AltName: Full=9,9'-di-cis-zeta-carotene desaturase;
DE   AltName: Full=Carotene 7,8-desaturase;
DE   Flags: Precursor;
GN   Name=ZDS1; Synonyms=ZDS;
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Luo R., Wurtzel E.T.;
RT   "A maize cDNA encoding zeta carotene desaturase.";
RL   (er) Plant Gene Register PGR99-118(1999).
CC   -!- FUNCTION: Catalyzes the conversion of zeta-carotene to lycopene via the
CC       intermediary of neurosporene. It carries out two consecutive
CC       desaturations (introduction of double bonds) at positions C-7 and C-7'.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=9,9'-di-cis-zeta-carotene + 2 a quinone = 7,7',9,9'-tetra-cis-
CC         lycopene + 2 a quinol; Xref=Rhea:RHEA:30955, ChEBI:CHEBI:24646,
CC         ChEBI:CHEBI:48716, ChEBI:CHEBI:62466, ChEBI:CHEBI:132124; EC=1.3.5.6;
CC   -!- COFACTOR:
CC       Name=NAD(+); Xref=ChEBI:CHEBI:57540; Evidence={ECO:0000305};
CC       Name=NADP(+); Xref=ChEBI:CHEBI:58349; Evidence={ECO:0000305};
CC       Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000305};
CC   -!- PATHWAY: Carotenoid biosynthesis; lycopene biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast. Plastid, chromoplast.
CC   -!- SIMILARITY: Belongs to the zeta carotene desaturase family.
CC       {ECO:0000305}.
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DR   EMBL; AF047490; AAD02462.1; -; mRNA.
DR   AlphaFoldDB; Q9ZTP4; -.
DR   SMR; Q9ZTP4; -.
DR   STRING; 4577.GRMZM2G454952_P01; -.
DR   PaxDb; Q9ZTP4; -.
DR   PRIDE; Q9ZTP4; -.
DR   MaizeGDB; 222743; -.
DR   eggNOG; KOG0029; Eukaryota.
DR   UniPathway; UPA00803; -.
DR   Proteomes; UP000007305; Unplaced.
DR   ExpressionAtlas; Q9ZTP4; baseline and differential.
DR   GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR   GO; GO:0009509; C:chromoplast; IEA:UniProtKB-SubCell.
DR   GO; GO:0052887; F:7,9,9'-tricis-neurosporene:quinone oxidoreductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052886; F:9,9'-dicis-carotene:quinone oxidoreductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016719; F:carotene 7,8-desaturase activity; IEA:UniProtKB-EC.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:UniProt.
DR   GO; GO:0016491; F:oxidoreductase activity; IBA:GO_Central.
DR   GO; GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.50.50.60; -; 1.
DR   InterPro; IPR002937; Amino_oxidase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR014103; Zeta_caro_desat.
DR   Pfam; PF01593; Amino_oxidase; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR02732; zeta_caro_desat; 1.
PE   2: Evidence at transcript level;
KW   Carotenoid biosynthesis; Chloroplast; Chromoplast; FAD; Flavoprotein; NAD;
KW   Oxidoreductase; Plastid; Reference proteome; Transit peptide.
FT   TRANSIT         1..?
FT                   /note="Chloroplast and chromoplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..570
FT                   /note="Zeta-carotene desaturase,
FT                   chloroplastic/chromoplastic"
FT                   /id="PRO_0000041608"
FT   REGION          1..33
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   570 AA;  63127 MW;  C7AD8F2FD62531E8 CRC64;
     MASVAATTTL APALAPRRAR PGTGLVPPRR ASAVAARSTV TSPTWRQRSQ RLFPPEPEHY
     RGPKLKVAII GAGLAGMSTA VELLDQGHEV DLYESRPFIG GKVGSFVDRQ GNHIEMGLHV
     FFGCYSNLFR LMKKVGADNN LLVKEHTHTF VNKGGTIGEL DFRFPVGAPL HGIQAFLRTN
     QLKVYDKARN AVALALSPVV RALVDPDGAL QQVRDLDDIS FSDWFMSKGG TRESITRMWD
     PVRYALGFID CDNISARCML TIFTLFATKT EASLLRMLKG SPDVYLSGPI KKYITDRGGR
     FHLRWGCREV LYEKSPDGET YVKGLLLTKA TSREIIKADA YVAACDVPGI KRLLPSEWRE
     WEMFDNIYKL DGVPVVTVQL RYNGWVTELQ DLEKSRQLQR AVGLDNLLYT ADADFSCFSD
     LALSSPADYY IEGQGSLIQA VLTPGDPYMP LPNEEIISKV QKQVVELFPS SRGLEVTWSS
     VVKIGQSLYR EAPGNDPFRP DQKTPVKNFF LSGSYTKQDY IDSMEGATLS GRRTSAYICG
     AGEELLALRK KLLIDDGEKA LGNVQVLQAS