ID   ZDS_SYNE7               Reviewed;         481 AA.
AC   Q31N27;
DT   19-OCT-2011, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Probable zeta-carotene desaturase;
DE            EC=1.3.5.6;
DE   AltName: Full=9,9'-di-cis-zeta-carotene desaturase;
DE   AltName: Full=Carotene 7,8-desaturase;
GN   Name=zds; Synonyms=crtQb; OrderedLocusNames=Synpcc7942_1512;
OS   Synechococcus elongatus (strain PCC 7942 / FACHB-805) (Anacystis nidulans
OS   R2).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus.
OX   NCBI_TaxID=1140;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7942 / FACHB-805;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Lykidis A., Richardson P.;
RT   "Complete sequence of chromosome 1 of Synechococcus elongatus PCC 7942.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the conversion of zeta-carotene to lycopene via the
CC       intermediary of neurosporene. It carries out two consecutive
CC       desaturations (introduction of double bonds) at positions C-7 and C-7'
CC       (By similarity). {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=9,9'-di-cis-zeta-carotene + 2 a quinone = 7,7',9,9'-tetra-cis-
CC         lycopene + 2 a quinol; Xref=Rhea:RHEA:30955, ChEBI:CHEBI:24646,
CC         ChEBI:CHEBI:48716, ChEBI:CHEBI:62466, ChEBI:CHEBI:132124; EC=1.3.5.6;
CC   -!- COFACTOR:
CC       Name=decylplastoquinone; Xref=ChEBI:CHEBI:72953;
CC         Evidence={ECO:0000250};
CC       Name=6-decylubiquinone; Xref=ChEBI:CHEBI:52020; Evidence={ECO:0000250};
CC       Note=Lipophilic quinones such as decyl-plastoquinone or decyl-
CC       ubiquinone. {ECO:0000250};
CC   -!- PATHWAY: Carotenoid biosynthesis; lycopene biosynthesis.
CC   -!- SIMILARITY: Belongs to the zeta carotene desaturase family.
CC       {ECO:0000305}.
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DR   EMBL; CP000100; ABB57542.1; -; Genomic_DNA.
DR   RefSeq; WP_011378061.1; NC_007604.1.
DR   AlphaFoldDB; Q31N27; -.
DR   SMR; Q31N27; -.
DR   STRING; 1140.Synpcc7942_1512; -.
DR   PRIDE; Q31N27; -.
DR   EnsemblBacteria; ABB57542; ABB57542; Synpcc7942_1512.
DR   KEGG; syf:Synpcc7942_1512; -.
DR   eggNOG; COG3349; Bacteria.
DR   HOGENOM; CLU_022687_1_1_3; -.
DR   OMA; MLTIFMM; -.
DR   OrthoDB; 630753at2; -.
DR   BioCyc; SYNEL:SYNPCC7942_1512-MON; -.
DR   UniPathway; UPA00803; -.
DR   GO; GO:0052887; F:7,9,9'-tricis-neurosporene:quinone oxidoreductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052886; F:9,9'-dicis-carotene:quinone oxidoreductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016719; F:carotene 7,8-desaturase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.50.50.60; -; 2.
DR   InterPro; IPR002937; Amino_oxidase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR014103; Zeta_caro_desat.
DR   Pfam; PF01593; Amino_oxidase; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR02732; zeta_caro_desat; 1.
PE   3: Inferred from homology;
KW   Carotenoid biosynthesis; Oxidoreductase.
FT   CHAIN           1..481
FT                   /note="Probable zeta-carotene desaturase"
FT                   /id="PRO_0000413009"
SQ   SEQUENCE   481 AA;  53278 MW;  3C74037C3939F6B9 CRC64;
     MRVAIVGAGL AGLAAAIDLV DAGHQVAIYD SRPFVGGKVG SWIDADGNHI EMGLHVFFFN
     YANLFALMRK VGAFENLLPK AHTHTFINKG GEVGELDFRF PIGAPFNGLK AFFTTSQLTW
     LDKLQNALAL GTSPLVRGIL DYEGAMKIIR ALDRISFADW FRSHGGSEGS LKRMWNPIAY
     ALGFIDTENI SARCMLTVFQ MFAAKTEASK LNLLAGSPAE YLHKPILDYI QARGATLHLR
     RRVREIEYTE TNGQTVVTGL QIADGDAVER VEADVYLAAC DVPGIQRLLP EAWRKWSEFD
     NIYKLDAVPV ATVQLRFDGW VTELGDREKR HQLDHATGLD NLLYTADADF SCFTDLALSS
     PKDYYRKGQG SLLQCVLTPG DPFIAMKNED IAQHVLKQVH ELFPSSRDLN MTWSNVVKLA
     QSLYREAPGM DPFRPDQKTP IANFFLAGSY TQQDYIDSME GATISGRRAA KAMLEAQAIA
     A