ID   ZDS_TARER               Reviewed;         587 AA.
AC   Q9FV46;
DT   02-NOV-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Zeta-carotene desaturase, chloroplastic/chromoplastic;
DE            EC=1.3.5.6;
DE   AltName: Full=9,9'-di-cis-zeta-carotene desaturase;
DE   AltName: Full=Carotene 7,8-desaturase;
DE   Flags: Precursor;
OS   Tagetes erecta (African marigold).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC   Heliantheae alliance; Tageteae; Tagetes.
OX   NCBI_TaxID=13708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=11292074; DOI=10.1023/a:1006417009203;
RA   Moehs C.P., Tian L., Osteryoung K.W., DellaPenna D.;
RT   "Analysis of carotenoid biosynthetic gene expression during marigold petal
RT   development.";
RL   Plant Mol. Biol. 45:281-293(2001).
CC   -!- FUNCTION: Catalyzes the conversion of zeta-carotene to lycopene via the
CC       intermediary of neurosporene. It carries out two consecutive
CC       desaturations (introduction of double bonds) at positions C-7 and C-7'
CC       (By similarity). {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=9,9'-di-cis-zeta-carotene + 2 a quinone = 7,7',9,9'-tetra-cis-
CC         lycopene + 2 a quinol; Xref=Rhea:RHEA:30955, ChEBI:CHEBI:24646,
CC         ChEBI:CHEBI:48716, ChEBI:CHEBI:62466, ChEBI:CHEBI:132124; EC=1.3.5.6;
CC   -!- COFACTOR:
CC       Name=NAD(+); Xref=ChEBI:CHEBI:57540; Evidence={ECO:0000305};
CC       Name=NADP(+); Xref=ChEBI:CHEBI:58349; Evidence={ECO:0000305};
CC       Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000305};
CC   -!- PATHWAY: Carotenoid biosynthesis; lycopene biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast. Plastid, chromoplast.
CC   -!- SIMILARITY: Belongs to the zeta carotene desaturase family.
CC       {ECO:0000305}.
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DR   EMBL; AF251013; AAG10425.1; -; mRNA.
DR   AlphaFoldDB; Q9FV46; -.
DR   SMR; Q9FV46; -.
DR   UniPathway; UPA00803; -.
DR   GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR   GO; GO:0009509; C:chromoplast; IEA:UniProtKB-SubCell.
DR   GO; GO:0052887; F:7,9,9'-tricis-neurosporene:quinone oxidoreductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052886; F:9,9'-dicis-carotene:quinone oxidoreductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016719; F:carotene 7,8-desaturase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.50.50.60; -; 1.
DR   InterPro; IPR002937; Amino_oxidase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR014103; Zeta_caro_desat.
DR   Pfam; PF01593; Amino_oxidase; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR02732; zeta_caro_desat; 1.
PE   2: Evidence at transcript level;
KW   Carotenoid biosynthesis; Chloroplast; Chromoplast; FAD; Flavoprotein; NAD;
KW   Oxidoreductase; Plastid; Transit peptide.
FT   TRANSIT         1..?
FT                   /note="Chloroplast and chromoplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..587
FT                   /note="Zeta-carotene desaturase,
FT                   chloroplastic/chromoplastic"
FT                   /id="PRO_0000041610"
SQ   SEQUENCE   587 AA;  65085 MW;  34D2DF150729B99C CRC64;
     MATSSTSSTT SLCFPATSAA GARTSFRTTD TFLRYRRSRQ LTRLKVRKAV VRSDLDRDVS
     DMRTNAPKGL FPPEPEHYRG PKLKVAIIGA GLAGMSTAVE LLDQGHEVDI YESRTFIGGK
     VGSFVDKQGN HIEMGLHVFF GCYNNLFRLL KKVGAEKNLL VKDHTHTFVN RGGELGELDF
     RFPVGAPLHG INAFLTTNQL KTYDKARNAV ALALSPVVRA LVDPDGAMTQ IRNLDNISFS
     EWFMSKGGTR TSIQRMWDPV AYALGFIDCD NISARCMLTI FSLFATKTEA SLLRMLKGSP
     DVYLSGPIRD YIIEKGGRFH LRWGCREILY EKSANGETYV TGLAMSKATQ KQIVKADVYI
     AACDVPGIKR LLPSNWREWE FFDNIYKLVG VPVVTVQLRY NGWVTELQDV ERSRQLRQAA
     GLDNLLYTPD ADFSCFADLA LASPEDYYIE GQGSLLQCVL TPGDPYMPLP NEEIISRVSK
     QVLALFPSSQ GLEVTWSSVV KIGQSLYREG PGKDPFRPDQ KTPVKNFFLA GSYTKQDYID
     SMEGATLSGR QASAFICDAG EELAALRKQL AAIQSIDSIG VDEMSLV