ID   CC172_BOVIN             Reviewed;         260 AA.
AC   Q2YDH9;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=Coiled-coil domain-containing protein 172;
GN   Name=CCDC172;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: May interact with TEKT2. {ECO:0000250|UniProtKB:Q810N9}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q810N9}. Cell
CC       projection, cilium {ECO:0000250|UniProtKB:Q6AXT4}. Note=In spermatozoa,
CC       localized in the middle piece, predominantly concentrated at the
CC       mitochondrial sheath of the flagella and to a lesser extent with outer
CC       dense fibers (ODF) (By similarity). Colocalized with TEKT2 at the
CC       perinuclear region (By similarity). {ECO:0000250|UniProtKB:Q6AXT4,
CC       ECO:0000250|UniProtKB:Q810N9}.
CC   -!- SIMILARITY: Belongs to the CCDC172 family. {ECO:0000305}.
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DR   EMBL; BC110215; AAI10216.1; -; mRNA.
DR   RefSeq; NP_001069301.1; NM_001075833.2.
DR   AlphaFoldDB; Q2YDH9; -.
DR   SMR; Q2YDH9; -.
DR   STRING; 9913.ENSBTAP00000043167; -.
DR   PaxDb; Q2YDH9; -.
DR   Ensembl; ENSBTAT00000045806; ENSBTAP00000043167; ENSBTAG00000032299.
DR   GeneID; 522573; -.
DR   KEGG; bta:522573; -.
DR   CTD; 374355; -.
DR   VEuPathDB; HostDB:ENSBTAG00000032299; -.
DR   VGNC; VGNC:26869; CCDC172.
DR   eggNOG; ENOG502S87V; Eukaryota.
DR   GeneTree; ENSGT00390000005203; -.
DR   InParanoid; Q2YDH9; -.
DR   OMA; LEMHKEG; -.
DR   OrthoDB; 1399070at2759; -.
DR   Proteomes; UP000009136; Chromosome 26.
DR   Bgee; ENSBTAG00000032299; Expressed in semen and 14 other tissues.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0097225; C:sperm midpiece; ISS:UniProtKB.
DR   InterPro; IPR029618; CCDC172.
DR   PANTHER; PTHR22419; PTHR22419; 1.
PE   2: Evidence at transcript level;
KW   Cell projection; Coiled coil; Cytoplasm; Reference proteome.
FT   CHAIN           1..260
FT                   /note="Coiled-coil domain-containing protein 172"
FT                   /id="PRO_0000344512"
FT   COILED          13..194
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   260 AA;  31183 MW;  DCAEA8F041CF8090 CRC64;
     MSLESLFQHI IFSEHQAEES RRLMREVRSE INRCREKIKK AAEQLNKEKI QLESKVQQFS
     EKAFLLQLLK THENALERQC NEITNQRNML LQTFEATKRR VTEEEEKFIK EITDFNNEYE
     LTKKRERLMK ENVKIQISDL ENQANILKME MKSMEHDSDL LNELQRQKNE LIQELSTLQR
     KLKGFEDKKH EAICTTKYLE AEKIKINEKP QNDAECLRLK KELELYKEDD MQSVHDALQT
     EIEFLELTLA QKDHQETNNL