ID   ZEAYB_MAIZE             Reviewed;         266 AA.
AC   K7TUP3;
DT   02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2013, sequence version 1.
DT   03-AUG-2022, entry version 43.
DE   RecName: Full=22 kDa alpha-zein 8 {ECO:0000303|PubMed:11691845};
DE   AltName: Full=Zein-alpha 22C2 {ECO:0000303|PubMed:11691845};
DE   Flags: Precursor;
GN   Name=AZS22-8 {ECO:0000303|PubMed:11691845};
GN   ORFNames=GRMZM2G044152 {ECO:0000305},
GN   ZEAMMB73_370768 {ECO:0000312|EMBL:AFW60335.1}, Zm.97200;
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND IDENTIFICATION.
RC   STRAIN=cv. B73;
RX   PubMed=19965430; DOI=10.1126/science.1178534;
RA   Schnable P.S., Ware D., Fulton R.S., Stein J.C., Wei F., Pasternak S.,
RA   Liang C., Zhang J., Fulton L., Graves T.A., Minx P., Reily A.D.,
RA   Courtney L., Kruchowski S.S., Tomlinson C., Strong C., Delehaunty K.,
RA   Fronick C., Courtney B., Rock S.M., Belter E., Du F., Kim K., Abbott R.M.,
RA   Cotton M., Levy A., Marchetto P., Ochoa K., Jackson S.M., Gillam B.,
RA   Chen W., Yan L., Higginbotham J., Cardenas M., Waligorski J., Applebaum E.,
RA   Phelps L., Falcone J., Kanchi K., Thane T., Scimone A., Thane N., Henke J.,
RA   Wang T., Ruppert J., Shah N., Rotter K., Hodges J., Ingenthron E.,
RA   Cordes M., Kohlberg S., Sgro J., Delgado B., Mead K., Chinwalla A.,
RA   Leonard S., Crouse K., Collura K., Kudrna D., Currie J., He R.,
RA   Angelova A., Rajasekar S., Mueller T., Lomeli R., Scara G., Ko A.,
RA   Delaney K., Wissotski M., Lopez G., Campos D., Braidotti M., Ashley E.,
RA   Golser W., Kim H., Lee S., Lin J., Dujmic Z., Kim W., Talag J., Zuccolo A.,
RA   Fan C., Sebastian A., Kramer M., Spiegel L., Nascimento L., Zutavern T.,
RA   Miller B., Ambroise C., Muller S., Spooner W., Narechania A., Ren L.,
RA   Wei S., Kumari S., Faga B., Levy M.J., McMahan L., Van Buren P.,
RA   Vaughn M.W., Ying K., Yeh C.-T., Emrich S.J., Jia Y., Kalyanaraman A.,
RA   Hsia A.-P., Barbazuk W.B., Baucom R.S., Brutnell T.P., Carpita N.C.,
RA   Chaparro C., Chia J.-M., Deragon J.-M., Estill J.C., Fu Y., Jeddeloh J.A.,
RA   Han Y., Lee H., Li P., Lisch D.R., Liu S., Liu Z., Nagel D.H., McCann M.C.,
RA   SanMiguel P., Myers A.M., Nettleton D., Nguyen J., Penning B.W.,
RA   Ponnala L., Schneider K.L., Schwartz D.C., Sharma A., Soderlund C.,
RA   Springer N.M., Sun Q., Wang H., Waterman M., Westerman R., Wolfgruber T.K.,
RA   Yang L., Yu Y., Zhang L., Zhou S., Zhu Q., Bennetzen J.L., Dawe R.K.,
RA   Jiang J., Jiang N., Presting G.G., Wessler S.R., Aluru S.,
RA   Martienssen R.A., Clifton S.W., McCombie W.R., Wing R.A., Wilson R.K.;
RT   "The B73 maize genome: complexity, diversity, and dynamics.";
RL   Science 326:1112-1115(2009).
RN   [2]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=11691845; DOI=10.1101/gr.197301;
RA   Song R., Llaca V., Linton E., Messing J.;
RT   "Sequence, regulation, and evolution of the maize 22-kD alpha zein gene
RT   family.";
RL   Genome Res. 11:1817-1825(2001).
CC   -!- FUNCTION: Zeins are major seed storage proteins. {ECO:0000305}.
CC   -!- MISCELLANEOUS: The alpha zeins of 19 kDa and 22 kDa account for 70% of
CC       the total zein fraction. They are encoded by a large multigene family.
CC   -!- MISCELLANEOUS: Structurally, 22K and 19K zeins are composed of nine
CC       adjacent, topologically antiparallel helices clustered within a
CC       distorted cylinder. {ECO:0000250|UniProtKB:P04698}.
CC   -!- SIMILARITY: Belongs to the zein family. {ECO:0000305}.
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DR   EMBL; CM000780; AFW60335.1; -; Genomic_DNA.
DR   AlphaFoldDB; K7TUP3; -.
DR   STRING; 4577.GRMZM2G044152_P01; -.
DR   PRIDE; K7TUP3; -.
DR   EnsemblPlants; Zm00001eb166620_T001; Zm00001eb166620_P001; Zm00001eb166620.
DR   Gramene; Zm00001eb166620_T001; Zm00001eb166620_P001; Zm00001eb166620.
DR   eggNOG; ENOG502R48M; Eukaryota.
DR   HOGENOM; CLU_073697_0_0_1; -.
DR   OMA; YSQFSLM; -.
DR   Proteomes; UP000007305; Chromosome 4.
DR   ExpressionAtlas; K7TUP3; baseline and differential.
DR   GO; GO:0045735; F:nutrient reservoir activity; IEA:UniProtKB-KW.
DR   InterPro; IPR002530; Zein.
DR   Pfam; PF01559; Zein; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Seed storage protein; Signal; Storage protein.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..266
FT                   /note="22 kDa alpha-zein 8"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_5007683683"
SQ   SEQUENCE   266 AA;  29005 MW;  1E15B55FA50FBBF7 CRC64;
     MATKILALLA LLALFVSATN AFIIPQCSLA PSAIIPQFLR PVTSMGFEHL AVQAYKLQQA
     LAASVLQQPI NQLQQQSLAH LTIQTIATQQ QQQFLPALSQ LDVVNPVAYL QQQVLASNPL
     ALANVAAYQQ QQQLQQFLPA LSQLAMVNPA AYLQQQQLLS SSPLVVGNAP TYLQQQLLQQ
     IVPALTQLAV ANPAAYLQQL LPFNQLTVSN SAAYLQQRQQ LLNPLAVPNP LVTAFLQQQQ
     LLPYSQFSLM NPALSWQQPI VGGAIF