ID   ZEAYW_MAIZE             Reviewed;         266 AA.
AC   P04699;
DT   13-AUG-1987, integrated into UniProtKB/Swiss-Prot.
DT   13-AUG-1987, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=22 kDa alpha-zein 8 {ECO:0000303|PubMed:11691845};
DE   AltName: Full=22 kDa zein ZA1/M1 {ECO:0000303|PubMed:16453440};
DE   AltName: Full=Zein-alpha ZA1/M1 {ECO:0000303|PubMed:16453440};
DE   Flags: Precursor;
GN   Name=AZS22-8 {ECO:0000303|PubMed:11691845};
OS   Zea mays (Maize).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Tripsacinae; Zea.
OX   NCBI_TaxID=4577;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=cv. Wisconsin 64A;
RX   PubMed=16453440; DOI=10.1002/j.1460-2075.1982.tb01360.x;
RA   Spena A., Viotti A., Pirrotta V.;
RT   "A homologous repetitive block structure underlies the heterogeneity of
RT   heavy and light chain zein genes.";
RL   EMBO J. 1:1589-1594(1982).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=cv. Wisconsin 64A;
RA   Spena A.;
RL   Submitted (APR-1983) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=cv. Wisconsin 64A;
RX   PubMed=16453609; DOI=10.1002/j.1460-2075.1985.tb03746.x;
RA   Viotti A., Cairo G., Vitale A., Sala E.;
RT   "Each zein gene class can produce polypeptides of different sizes.";
RL   EMBO J. 4:1103-1110(1985).
RN   [4]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=11691845; DOI=10.1101/gr.197301;
RA   Song R., Llaca V., Linton E., Messing J.;
RT   "Sequence, regulation, and evolution of the maize 22-kD alpha zein gene
RT   family.";
RL   Genome Res. 11:1817-1825(2001).
CC   -!- FUNCTION: Zeins are major seed storage proteins. {ECO:0000305}.
CC   -!- MISCELLANEOUS: The alpha zeins of 19 kDa and 22 kDa account for 70% of
CC       the total zein fraction. They are encoded by a large multigene family.
CC   -!- MISCELLANEOUS: Structurally, 22K and 19K zeins are composed of nine
CC       adjacent, topologically antiparallel helices clustered within a
CC       distorted cylinder. {ECO:0000250|UniProtKB:P04698}.
CC   -!- SIMILARITY: Belongs to the zein family. {ECO:0000305}.
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DR   EMBL; V01475; CAA24722.1; -; Genomic_DNA.
DR   PIR; B22831; B22831.
DR   AlphaFoldDB; P04699; -.
DR   PaxDb; P04699; -.
DR   MaizeGDB; 58096; -.
DR   Proteomes; UP000007305; Unplaced.
DR   ExpressionAtlas; P04699; baseline and differential.
DR   GO; GO:0045735; F:nutrient reservoir activity; IEA:UniProtKB-KW.
DR   InterPro; IPR002530; Zein.
DR   Pfam; PF01559; Zein; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Seed storage protein; Signal; Storage protein.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..266
FT                   /note="22 kDa alpha-zein 8"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000041627"
SQ   SEQUENCE   266 AA;  28988 MW;  670227E05256C0D2 CRC64;
     MATKILALLA LLALFVSATN AFIIPQCSLA PSAIIPQFLP PVTSMGFEHL AVQAYRLQQA
     LAASVLQQPI NQLQQQSLAH LTIQTIATQQ QQQFLPALSQ LDVVNPVAYL QQQLLASNPL
     ALANVAAYQQ QQQLQQFLPA LSQLAMVNPA AYLQQQQLLS SSPLAVGNAP TYLQQQLLQQ
     IVPALTQLAV ANPAAYLQQL LPFNQLTVSN SAAYLQQRQQ LLNPLEVPNP LVAAFLQQQQ
     LLPYSQFSLM NPALSWQQPI VGGAIF