ID   CC174_CHICK             Reviewed;         514 AA.
AC   Q5ZIH9;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Coiled-coil domain-containing protein 174;
GN   Name=CCDC174; ORFNames=RCJMB04_26a16;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Probably involved in neuronal development.
CC       {ECO:0000250|UniProtKB:Q6PII3}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q6PII3}.
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DR   EMBL; AJ720805; CAG32464.1; -; mRNA.
DR   AlphaFoldDB; Q5ZIH9; -.
DR   SMR; Q5ZIH9; -.
DR   STRING; 9031.ENSGALP00000010416; -.
DR   PaxDb; Q5ZIH9; -.
DR   PRIDE; Q5ZIH9; -.
DR   VEuPathDB; HostDB:geneid_416044; -.
DR   eggNOG; ENOG502QWJ9; Eukaryota.
DR   InParanoid; Q5ZIH9; -.
DR   PhylomeDB; Q5ZIH9; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   InterPro; IPR025066; CCDC174-like.
DR   PANTHER; PTHR15885; PTHR15885; 1.
DR   Pfam; PF13300; DUF4078; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Nucleus; Reference proteome.
FT   CHAIN           1..514
FT                   /note="Coiled-coil domain-containing protein 174"
FT                   /id="PRO_0000251959"
FT   REGION          42..83
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          137..162
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          270..291
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          306..490
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          66..98
FT                   /evidence="ECO:0000255"
FT   COILED          203..227
FT                   /evidence="ECO:0000255"
FT   COILED          266..321
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        61..83
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        143..162
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        306..390
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        402..459
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        467..484
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   514 AA;  59323 MW;  C58DAD2DAC6D096A CRC64;
     MDRRKKPLDV AASSLVDLKA ELFRKQEEFK KEKLLKDAGI FAKPKPSNKK PSIWTKQNTG
     VAKRAEKDIE QKAEEDQTLD QSRKKLEEKA KLYEKMTKGD FPDEETEDLY LVDFTQKIID
     KQREVQELYQ NEAAIKTLEK ETDDEEIEPE MEIPPPEDPD EEWVDYVDSL GRSRRCMKKD
     LPSILKMDQE LQGKRLDPDG NTLLSEDMKR ELQRQQWEKE EEEALRKPMG PIHYEDIREN
     EARQLGVGYF AFSRDQDLRH KQRATLDMLR EQTLDQRTKR EQLKEKRKAA LESRLSKLRA
     RKVKKLREEG LEEEAERLEN GEVKDTTSPV EAEPEVPRPS RKVEVVIQER RDTKPGVPYV
     REWDKGKELM FGQWSKKQEE LRDERDPEFA PPSDYFMGQK KDDGYSSQNL NSPETSPGKT
     EPEISENQKK LSVQASTHRA EVVPPSVQAY SNNVQGGLAP AEASGSDAED GSTSAETDSS
     DEQDGVPSAH PLHLWCSDTC QPSNAGLWLW PLRI