ID   ZFAN3_XENLA             Reviewed;         226 AA.
AC   Q66J85;
DT   07-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=AN1-type zinc finger protein 3 homolog;
GN   Name=zfand3;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; BC081022; AAH81022.1; -; mRNA.
DR   RefSeq; NP_001087635.1; NM_001094166.1.
DR   AlphaFoldDB; Q66J85; -.
DR   SMR; Q66J85; -.
DR   DNASU; 447459; -.
DR   GeneID; 447459; -.
DR   KEGG; xla:447459; -.
DR   CTD; 447459; -.
DR   Xenbase; XB-GENE-947499; zfand3.S.
DR   OMA; SVHIQNG; -.
DR   OrthoDB; 1440530at2759; -.
DR   Proteomes; UP000186698; Chromosome 5S.
DR   Bgee; 447459; Expressed in blastula and 19 other tissues.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   Gene3D; 4.10.1110.10; -; 1.
DR   InterPro; IPR035896; AN1-like_Znf.
DR   InterPro; IPR002653; Znf_A20.
DR   InterPro; IPR000058; Znf_AN1.
DR   Pfam; PF01754; zf-A20; 1.
DR   Pfam; PF01428; zf-AN1; 1.
DR   SMART; SM00259; ZnF_A20; 1.
DR   SMART; SM00154; ZnF_AN1; 1.
DR   SUPFAM; SSF118310; SSF118310; 1.
DR   PROSITE; PS51036; ZF_A20; 1.
DR   PROSITE; PS51039; ZF_AN1; 1.
PE   2: Evidence at transcript level;
KW   Metal-binding; Reference proteome; Zinc; Zinc-finger.
FT   CHAIN           1..226
FT                   /note="AN1-type zinc finger protein 3 homolog"
FT                   /id="PRO_0000076373"
FT   ZN_FING         12..44
FT                   /note="A20-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00451"
FT   ZN_FING         150..199
FT                   /note="AN1-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT   REGION          42..149
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        46..90
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        118..149
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         18
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00451"
FT   BINDING         20
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00451"
FT   BINDING         32
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00451"
FT   BINDING         35
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00451"
FT   BINDING         156
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT   BINDING         159
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT   BINDING         173
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT   BINDING         175
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT   BINDING         180
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT   BINDING         183
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT   BINDING         189
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
FT   BINDING         191
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00449"
SQ   SEQUENCE   226 AA;  25013 MW;  5DF049882D1446D6 CRC64;
     MGDTGSERSN APSLPPRCPC GFWGSSKTMN LCSKCFADFQ KKQPDEDTAP STSSSQSDLF
     PSETDSDNGN TSIPTPTVNP TQQLPTELNV DSPSKEDCGP CTDSAHVSLT TPSKRSCDSD
     SQSEDDTSPM KRPRLLDSGD RPDNSSRSKQ KSRRRCFRCQ IKLELVQQEL GSCRCGYVFC
     MLHRLPEQHD CTFDHMGRGR EEAIMKMVKL DRKVGRSCQR IGEGCS