ID   CC174_RAT               Reviewed;         474 AA.
AC   Q5PQS7;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 2.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Coiled-coil domain-containing protein 174;
GN   Name=Ccdc174;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Probably involved in neuronal development.
CC       {ECO:0000250|UniProtKB:Q6PII3}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q6PII3}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAH87050.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; BC087050; AAH87050.1; ALT_INIT; mRNA.
DR   RefSeq; NP_001009659.2; NM_001009659.2.
DR   AlphaFoldDB; Q5PQS7; -.
DR   SMR; Q5PQS7; -.
DR   STRING; 10116.ENSRNOP00000013498; -.
DR   iPTMnet; Q5PQS7; -.
DR   PhosphoSitePlus; Q5PQS7; -.
DR   PaxDb; Q5PQS7; -.
DR   PRIDE; Q5PQS7; -.
DR   GeneID; 297458; -.
DR   KEGG; rno:297458; -.
DR   CTD; 51244; -.
DR   RGD; 1305225; Ccdc174.
DR   eggNOG; ENOG502QWJ9; Eukaryota.
DR   InParanoid; Q5PQS7; -.
DR   OrthoDB; 1585377at2759; -.
DR   PhylomeDB; Q5PQS7; -.
DR   PRO; PR:Q5PQS7; -.
DR   Proteomes; UP000002494; Unplaced.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   InterPro; IPR025066; CCDC174-like.
DR   PANTHER; PTHR15885; PTHR15885; 1.
DR   Pfam; PF13300; DUF4078; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Nucleus; Phosphoprotein; Reference proteome.
FT   CHAIN           1..474
FT                   /note="Coiled-coil domain-containing protein 174"
FT                   /id="PRO_0000251958"
FT   REGION          39..86
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          129..170
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          309..372
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          389..461
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          64..98
FT                   /evidence="ECO:0000255"
FT   COILED          276..317
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        48..62
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        63..86
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        129..144
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        145..159
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        315..331
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        354..372
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        406..422
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        429..461
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         206
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q6PII3"
SQ   SEQUENCE   474 AA;  54449 MW;  D821E8DD339A1AD6 CRC64;
     MDRKKKPLDV TASSLVDLKA ELFRKQEEFK QEKLLKDSGV FGKPKTSNKK PSIWSKQNAG
     VSSRAEKDAE QKLEEQKTLD KSREKLEEKA KLYEKMTKGD FLDEEVEDMY LVDFTQKIID
     KRKEMEVLGA TRDSRIKEER DAAVAAANDD DDEEEFSEKD IPPPQDPSEE WVDYVDSLGR
     SRRCMRKDLP SLLEMDKNLQ GRLFVSPANE KTLLSEDMRK ELQRQQWEEE EREALKKPMG
     PIHYEDIREN EARQLGVGYF AFARDKELRN KQMKTLEMLR EQTTDQRIKR ENIKEKRKAI
     LEARLAKLRQ KKMKKSKVDG TEEESRADGV VTEPSEPKSV PAPPPVAQSS KVEVIIQERK
     DSKPGVPHIR EWDRGKDFSF GFWSKKQSEL RAERDPEFAP PSNYFVGQKR TGSLSSQPWS
     RPGAAPSDLG HSSGQSQEPS SSHTSTPASE SSPQAPTVTF QTLDDMISYY KQVT