ZFP1_ORYSJ
ID ZFP1_ORYSJ Reviewed; 523 AA.
AC Q5QLR5; Q5QLR6;
DT 07-JUN-2017, integrated into UniProtKB/Swiss-Prot.
DT 04-JAN-2005, sequence version 1.
DT 03-AUG-2022, entry version 141.
DE RecName: Full=Probable E3 ubiquitin-protein ligase ZFP1 {ECO:0000305};
DE Short=OsZFP1 {ECO:0000303|PubMed:28220688};
DE EC=2.3.2.27 {ECO:0000305};
GN Name=ZFP1 {ECO:0000303|PubMed:28220688};
GN OrderedLocusNames=Os01g0667700 {ECO:0000312|EMBL:BAF05724.1},
GN LOC_Os01g47740 {ECO:0000305};
GN ORFNames=OsJ_02947 {ECO:0000312|EMBL:EAZ13026.1},
GN OSJNBb0063G05.28-1 {ECO:0000312|EMBL:BAD73651.1},
GN OSJNBb0063G05.28-2 {ECO:0000312|EMBL:BAD73652.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447438; DOI=10.1038/nature01184;
RA Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT "The genome sequence and structure of rice chromosome 1.";
RL Nature 420:312-316(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP LACK OF INDUCTION BY SALT STRESS.
RX PubMed=27118216; DOI=10.1111/ppl.12459;
RA Hwang S.G., Kim J.J., Lim S.D., Park Y.C., Moon J.C., Jang C.S.;
RT "Molecular dissection of Oryza sativa salt-induced RING Finger Protein 1
RT (OsSIRP1): possible involvement in the sensitivity response to salinity
RT stress.";
RL Physiol. Plantarum 158:168-179(2016).
RN [8]
RP INTERACTION WITH DJA6, AND MUTAGENESIS OF HIS-491.
RX PubMed=28220688; DOI=10.1111/mpp.12546;
RA Zhong X., Yang J., Shi Y., Wang X., Wang G.L.;
RT "The DnaJ protein OsDjA6 negatively regulates rice innate immunity to the
RT blast fungus Magnaporthe oryzae.";
RL Mol. Plant Pathol. 19:607-614(2018).
CC -!- FUNCTION: Probable E3 ubiquitin-protein ligase.
CC {ECO:0000250|UniProtKB:Q6AVN2}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000250|UniProtKB:Q6AVN2};
CC -!- PATHWAY: Protein modification; protein ubiquitination. {ECO:0000305}.
CC -!- SUBUNIT: Interacts with DJA6. {ECO:0000269|PubMed:28220688}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q5QLR5-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q5QLR5-2; Sequence=VSP_058965;
CC -!- INDUCTION: Not induced by salt stress. {ECO:0000269|PubMed:27118216}.
CC -!- DOMAIN: The RING-type zinc finger domain mediates binding to an E2
CC ubiquitin-conjugating enzyme. {ECO:0000250}.
CC -!- MISCELLANEOUS: [Isoform 2]: May be due to a competing acceptor splice
CC site. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the RING-type zinc finger family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP003760; BAD73651.1; -; Genomic_DNA.
DR EMBL; AP003760; BAD73652.1; -; Genomic_DNA.
DR EMBL; AP008207; BAF05724.1; -; Genomic_DNA.
DR EMBL; AP014957; BAS73592.1; -; Genomic_DNA.
DR EMBL; AP014957; BAS73593.1; -; Genomic_DNA.
DR EMBL; CM000138; EAZ13026.1; -; Genomic_DNA.
DR EMBL; AK067662; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; AK069011; BAG91209.1; -; mRNA.
DR RefSeq; XP_015615383.1; XM_015759897.1. [Q5QLR5-2]
DR RefSeq; XP_015615392.1; XM_015759906.1. [Q5QLR5-1]
DR AlphaFoldDB; Q5QLR5; -.
DR SMR; Q5QLR5; -.
DR STRING; 4530.OS01T0667700-02; -.
DR PRIDE; Q5QLR5; -.
DR EnsemblPlants; Os01t0667700-01; Os01t0667700-01; Os01g0667700. [Q5QLR5-1]
DR EnsemblPlants; Os01t0667700-02; Os01t0667700-02; Os01g0667700. [Q5QLR5-2]
DR EnsemblPlants; Os01t0667700-04; Os01t0667700-04; Os01g0667700. [Q5QLR5-1]
DR GeneID; 4326322; -.
DR Gramene; Os01t0667700-01; Os01t0667700-01; Os01g0667700. [Q5QLR5-1]
DR Gramene; Os01t0667700-02; Os01t0667700-02; Os01g0667700. [Q5QLR5-2]
DR Gramene; Os01t0667700-04; Os01t0667700-04; Os01g0667700. [Q5QLR5-1]
DR KEGG; osa:4326322; -.
DR eggNOG; KOG0800; Eukaryota.
DR InParanoid; Q5QLR5; -.
DR OMA; CGHRYHE; -.
DR OrthoDB; 646422at2759; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000000763; Chromosome 1.
DR Proteomes; UP000007752; Chromosome 1.
DR Proteomes; UP000059680; Chromosome 1.
DR ExpressionAtlas; Q5QLR5; baseline and differential.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IBA:GO_Central.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR Gene3D; 3.30.40.10; -; 1.
DR InterPro; IPR045191; MBR1/2-like.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR22937; PTHR22937; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00184; RING; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Metal-binding; Reference proteome; Transferase;
KW Ubl conjugation pathway; Zinc; Zinc-finger.
FT CHAIN 1..523
FT /note="Probable E3 ubiquitin-protein ligase ZFP1"
FT /id="PRO_0000440261"
FT ZN_FING 471..512
FT /note="RING-type; atypical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
FT REGION 18..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..43
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 273
FT /note="P -> PA (in isoform 2)"
FT /id="VSP_058965"
FT MUTAGEN 491
FT /note="H->Y: Increases protein stability."
FT /evidence="ECO:0000269|PubMed:28220688"
SQ SEQUENCE 523 AA; 57682 MW; 4BDAA204B0C8384B CRC64;
MAYRNTVCTP QVIDLETEQG HSHIHSESFN RTGNDSSDQG AQHAVRGVGN ATNIGLSDMR
SYYDAGMNHP HQPVHNLPPN LGVDSGFVFP SSMYNPCMST TSMNQYVSHT QSFGLPSNQV
VLGSMDEGSR NENAGESARG FIKRKNAAVA GSYHCANGFA SSSSSHASLN PTHRPWDPSF
ESNVLPNTAS YNPSEYHSQT SWPSMEGSSI PSNGFNLMGA HPESAQHGNY AFPTSHISQC
FQPTSNTWIS QSANGIADGI PQWEYVNGMN NAPGRFSRSG MTETVNGSFR EYQNGPSTLC
RGPLPYFHQH AGMHAHNLLD HTQVQAPYQQ CHNNPVLHGV NHSGNRFHLG PRIPVLFSNS
ERTFGPPHHP LLANPVNHRN IRILPPEHAT IMDFSRLYEV SNVVDEHRDM RLDIDSMTYE
ELLALEEQIG DVNTGLAKSY IVEKLKTSLF VPGSSCMSNK SSESSMENDA CIICQEEYQV
KECIGTLDCG HRYHEDCIKQ WLMVKNLCPI CKTTALSTGR RSG
