ZFP36_ORYSJ
ID ZFP36_ORYSJ Reviewed; 220 AA.
AC Q75KE5; A3AJF7; Q7X9P9;
DT 25-OCT-2017, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 136.
DE RecName: Full=Zinc finger protein 36 {ECO:0000303|PubMed:25071223};
DE AltName: Full=Protein BROAD-SPECTRUM RESISTANCE DIGU 1 {ECO:0000303|PubMed:28666113};
GN Name=ZFP36 {ECO:0000303|PubMed:25071223};
GN Synonyms=BSR-D1 {ECO:0000303|PubMed:28666113};
GN OrderedLocusNames=Os03g0437200 {ECO:0000312|EMBL:BAF12358.1},
GN LOC_Os03g32230 {ECO:0000312|EMBL:ABF96814.1};
GN ORFNames=OsJ_11395 {ECO:0000312|EMBL:EAZ27446.1},
GN OSJNBa0054H04.4 {ECO:0000312|EMBL:AAR89021.1},
GN OSJNBb0034P05.8 {ECO:0000312|EMBL:AAU89183.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=18987217; DOI=10.1104/pp.108.128579;
RA Yilmaz A., Nishiyama M.Y., Fuentes B.G., Souza G.M., Janies D., Gray J.,
RA Grotewold E.;
RT "GRASSIUS: a platform for comparative regulatory genomics across the
RT grasses.";
RL Plant Physiol. 149:171-180(2009).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND INDUCTION.
RC STRAIN=cv. Jiu Caiqing;
RX PubMed=25071223; DOI=10.1093/jxb/eru313;
RA Zhang H., Liu Y., Wen F., Yao D., Wang L., Guo J., Ni L., Zhang A., Tan M.,
RA Jiang M.;
RT "A novel rice C2H2-type zinc finger protein, ZFP36, is a key player
RT involved in abscisic acid-induced antioxidant defence and oxidative stress
RT tolerance in rice.";
RL J. Exp. Bot. 65:5795-5809(2014).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16109971; DOI=10.1101/gr.3869505;
RG The rice chromosome 3 sequencing consortium;
RA Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B.,
RA Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T.,
RA Fadrosh D., Bera J., Weaver B., Jin S., Johri S., Reardon M., Webb K.,
RA Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T.,
RA Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R.,
RA Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J.,
RA Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S.,
RA Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M.,
RA Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M.,
RA Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L.,
RA O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R.,
RA Jin W., Lee H.R., Jiang J., Jackson S.;
RT "Sequence, annotation, and analysis of synteny between rice chromosome 3
RT and diverged grass species.";
RL Genome Res. 15:1284-1291(2005).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [6]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [8]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [9]
RP MISCELLANEOUS.
RX PubMed=28666113; DOI=10.1016/j.cell.2017.06.008;
RA Li W., Zhu Z., Chern M., Yin J., Yang C., Ran L., Cheng M., He M., Wang K.,
RA Wang J., Zhou X., Zhu X., Chen Z., Wang J., Zhao W., Ma B., Qin P.,
RA Chen W., Wang Y., Liu J., Wang W., Wu X., Li P., Wang J., Zhu L., Li S.,
RA Chen X.;
RT "A natural allele of a transcription factor in rice confers broad-spectrum
RT blast resistance.";
RL Cell 170:114-126(2017).
CC -!- FUNCTION: Probable transcription factor involved in abscisic acid (ABA)
CC signaling. Required for the regulation of the cross-talk between NADPH
CC oxidase, hydrogen peroxide and MAP kinase in ABA signaling. Regulates
CC the expression of the NADPH oxidase genes RBOHB and RBOHE, and the MAPK
CC genes MPK1, MPK4, MPK5, MPK7 and MPK14. Regulates ABA-induced hydrogen
CC peroxide production and antioxidant defense. Required for tolerance to
CC water stress and oxidative stress. {ECO:0000269|PubMed:25071223}.
CC -!- INDUCTION: Induced by abscisic acid (ABA) and hydrogen peroxide.
CC {ECO:0000269|PubMed:25071223}.
CC -!- MISCELLANEOUS: Plants over-expressing ZFP36 display enhanced tolerance
CC to drought and oxidative stresses (PubMed:25071223). A natural allele
CC in the promoter of ZFP36 in the durably resistant rice variety Digu
CC confers broad-spectrum resistance to rice blast (Magnaporthe oryzae)
CC (PubMed:28666113). {ECO:0000269|PubMed:25071223,
CC ECO:0000269|PubMed:28666113}.
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DR EMBL; HQ858823; ADX60235.1; -; mRNA.
DR EMBL; AY295345; AAP51130.1; -; mRNA.
DR EMBL; AC106887; AAR89021.1; -; Genomic_DNA.
DR EMBL; AC147803; AAU89183.1; -; Genomic_DNA.
DR EMBL; DP000009; ABF96814.1; -; Genomic_DNA.
DR EMBL; AP008209; BAF12358.1; -; Genomic_DNA.
DR EMBL; AP014959; BAS84848.1; -; Genomic_DNA.
DR EMBL; CM000140; EAZ27446.1; -; Genomic_DNA.
DR EMBL; AK059839; BAG87161.1; -; mRNA.
DR RefSeq; XP_015629109.1; XM_015773623.1.
DR AlphaFoldDB; Q75KE5; -.
DR STRING; 4530.OS03T0437200-01; -.
DR PaxDb; Q75KE5; -.
DR PRIDE; Q75KE5; -.
DR EnsemblPlants; Os03t0437200-01; Os03t0437200-01; Os03g0437200.
DR GeneID; 4333197; -.
DR Gramene; Os03t0437200-01; Os03t0437200-01; Os03g0437200.
DR KEGG; osa:4333197; -.
DR eggNOG; KOG1721; Eukaryota.
DR HOGENOM; CLU_059471_1_1_1; -.
DR InParanoid; Q75KE5; -.
DR OMA; KRWAREE; -.
DR OrthoDB; 1395906at2759; -.
DR Proteomes; UP000000763; Chromosome 3.
DR Proteomes; UP000007752; Chromosome 3.
DR Proteomes; UP000059680; Chromosome 3.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006979; P:response to oxidative stress; IMP:UniProtKB.
DR GO; GO:0009414; P:response to water deprivation; IMP:UniProtKB.
DR InterPro; IPR044653; AZF1/2/3-like.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR45988; PTHR45988; 1.
DR SMART; SM00355; ZnF_C2H2; 2.
DR SUPFAM; SSF57667; SSF57667; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 2.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE 2: Evidence at transcript level;
KW DNA-binding; Metal-binding; Reference proteome; Repeat; Stress response;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..220
FT /note="Zinc finger protein 36"
FT /id="PRO_0000441774"
FT ZN_FING 73..95
FT /note="C2H2-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 135..157
FT /note="C2H2-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT REGION 90..134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 117..133
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 58
FT /note="N -> S (in Ref. 2; AAP51130)"
FT /evidence="ECO:0000305"
FT CONFLICT 100
FT /note="S -> F (in Ref. 7; EAZ27446)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 220 AA; 22804 MW; 541EF5115A8886F7 CRC64;
MTAALQALLD PTALSLGLPT PAINKEEYLA ICLAALACTR AGKALVGVGG QQQVQACNKW
LCPAPAAPEE LRFRCTVCGK AFASYQALGG HKSSHRKPPS PGDHYGAAAA AQQLASAGDS
KEDSASSAAG STGPHRCTIC RRSFATGQAL GGHKRCHYWD GTSVSVSVSA SASAASSAVR
NFDLNLMPLP ESTAAAGIKR WAEEEEVQSP LPVKKLRMSN
