ID   ZFPL1_AEDAE             Reviewed;         290 AA.
AC   Q16N38;
DT   25-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   25-JUL-2006, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Zinc finger protein-like 1 homolog;
GN   ORFNames=AAEL012105;
OS   Aedes aegypti (Yellowfever mosquito) (Culex aegypti).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC   Culicinae; Aedini; Aedes; Stegomyia.
OX   NCBI_TaxID=7159;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LVPib12;
RX   PubMed=17510324; DOI=10.1126/science.1138878;
RA   Nene V., Wortman J.R., Lawson D., Haas B.J., Kodira C.D., Tu Z.J.,
RA   Loftus B.J., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., Lobo N.F.,
RA   Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., Sinkins S.P.,
RA   Hogenkamp D.G., Amedeo P., Arensburger P., Atkinson P.W., Bidwell S.L.,
RA   Biedler J., Birney E., Bruggner R.V., Costas J., Coy M.R., Crabtree J.,
RA   Crawford M., DeBruyn B., DeCaprio D., Eiglmeier K., Eisenstadt E.,
RA   El-Dorry H., Gelbart W.M., Gomes S.L., Hammond M., Hannick L.I.,
RA   Hogan J.R., Holmes M.H., Jaffe D., Johnston S.J., Kennedy R.C., Koo H.,
RA   Kravitz S., Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S.,
RA   Lovin D.D., Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P.,
RA   Mori A., Nascimento A.L., Naveira H.F., Nusbaum C., O'Leary S.B., Orvis J.,
RA   Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.-H.C., Roth C.W.,
RA   Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O.,
RA   Tubio J.M.C., Vanzee J.P., Verjovski-Almeida S., Werner D., White O.R.,
RA   Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., Soares M.B.,
RA   Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., Paulsen I.T.,
RA   Dimopoulos G., Collins F.H., Bruce B., Fraser-Liggett C.M., Severson D.W.;
RT   "Genome sequence of Aedes aegypti, a major arbovirus vector.";
RL   Science 316:1718-1723(2007).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the ZFPL1 family. {ECO:0000305}.
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DR   EMBL; CH477841; EAT35748.1; -; Genomic_DNA.
DR   RefSeq; XP_001655852.1; XM_001655802.1.
DR   AlphaFoldDB; Q16N38; -.
DR   STRING; 7159.AAEL012105-PA; -.
DR   PRIDE; Q16N38; -.
DR   GeneID; 5575829; -.
DR   KEGG; aag:5575829; -.
DR   VEuPathDB; VectorBase:AAEL012105; -.
DR   eggNOG; KOG3970; Eukaryota.
DR   HOGENOM; CLU_075387_0_0_1; -.
DR   InParanoid; Q16N38; -.
DR   OMA; PSGHQCP; -.
DR   OrthoDB; 807302at2759; -.
DR   PhylomeDB; Q16N38; -.
DR   Proteomes; UP000008820; Chromosome 1.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR039043; ZFPL1.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR12981; PTHR12981; 1.
DR   Pfam; PF13639; zf-RING_2; 1.
DR   SMART; SM00184; RING; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   3: Inferred from homology;
KW   Membrane; Metal-binding; Reference proteome; Transmembrane;
KW   Transmembrane helix; Zinc; Zinc-finger.
FT   CHAIN           1..290
FT                   /note="Zinc finger protein-like 1 homolog"
FT                   /id="PRO_0000355177"
FT   TRANSMEM        249..269
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   ZN_FING         1..43
FT                   /note="B box-type; degenerate"
FT   ZN_FING         53..101
FT                   /note="RING-type; atypical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
FT   REGION          156..175
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   290 AA;  32597 MW;  0F006F71369FD049 CRC64;
     MGLCKCPKRQ VTTQFCFEHR VNVCENCMVV NHTKCTVQSY IQWLKDSDFD SSCPLCGSPL
     DNEDCVRLIC YHVFHWKCLN AKQQSLPANT APGGHTCPTC SDPIFPPVNL VSPVADVLRT
     RLGQVNWARN VLELPLLSED KPDYYTTATT SAGVHNGNTF ASSMSQTRSN ERPESPHSIV
     NMESYVSNAS PALDFHASSR RPLLARESPI GASDRDDNKY KRRTPQEIFS RWSRRLYAPS
     SKPPWRRTWF LVLGGCIGFV CIIYVLATLG RRGGDGEVGL IYNRNLPHEE