ID   ZFPL1_BOVIN             Reviewed;         312 AA.
AC   Q2YDD3; Q1JP84;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Zinc finger protein-like 1;
GN   Name=ZFPL1;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-257.
RX   PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA   Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA   Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT   "Characterization of 954 bovine full-CDS cDNA sequences.";
RL   BMC Genomics 6:166-166(2005).
CC   -!- FUNCTION: Required for cis-Golgi integrity and efficient ER to Golgi
CC       transport. Involved in the maintenance of the integrity of the cis-
CC       Golgi, possibly via its interaction with GOLGA2/GM130 (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with GOLGA2/GM130. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, cis-Golgi network membrane
CC       {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
CC   -!- DOMAIN: The B box-type and RING-type zinc fingers although degenerate
CC       play a central role in function of the protein. {ECO:0000250}.
CC   -!- PTM: Phosphorylated. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ZFPL1 family. {ECO:0000305}.
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DR   EMBL; BC110275; AAI10276.1; -; mRNA.
DR   EMBL; BT025470; ABF57426.1; -; mRNA.
DR   RefSeq; NP_001069740.1; NM_001076272.1.
DR   RefSeq; XP_010819442.1; XM_010821140.2.
DR   AlphaFoldDB; Q2YDD3; -.
DR   STRING; 9913.ENSBTAP00000020585; -.
DR   PaxDb; Q2YDD3; -.
DR   PRIDE; Q2YDD3; -.
DR   Ensembl; ENSBTAT00000020585; ENSBTAP00000020585; ENSBTAG00000015479.
DR   Ensembl; ENSBTAT00000084470; ENSBTAP00000069206; ENSBTAG00000015479.
DR   GeneID; 613442; -.
DR   KEGG; bta:613442; -.
DR   CTD; 7542; -.
DR   VEuPathDB; HostDB:ENSBTAG00000015479; -.
DR   VGNC; VGNC:37170; ZFPL1.
DR   eggNOG; KOG3970; Eukaryota.
DR   GeneTree; ENSGT00390000009753; -.
DR   InParanoid; Q2YDD3; -.
DR   OMA; PNCALCN; -.
DR   OrthoDB; 807302at2759; -.
DR   Proteomes; UP000009136; Chromosome 29.
DR   GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
DR   InterPro; IPR039043; ZFPL1.
DR   PANTHER; PTHR12981; PTHR12981; 1.
PE   2: Evidence at transcript level;
KW   ER-Golgi transport; Golgi apparatus; Membrane; Metal-binding;
KW   Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix;
KW   Transport; Zinc; Zinc-finger.
FT   CHAIN           1..312
FT                   /note="Zinc finger protein-like 1"
FT                   /id="PRO_0000342147"
FT   TOPO_DOM        1..268
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        269..289
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        290..312
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   ZN_FING         1..43
FT                   /note="B box-type; degenerate"
FT   ZN_FING         53..101
FT                   /note="RING-type; degenerate"
FT   REGION          144..233
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        147..177
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        214..233
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   312 AA;  34401 MW;  0DCA441C2ABC7C72 CRC64;
     MGLCKCPKRK VTNLFCFEHR VNVCEHCLVA NHAKCIVQSY LQWLQDSDYN PNCRLCNIPL
     AARETTRLIC YDLFHWACLN ERAAQLPRNT APAGYQCPSC SGPIFPPTNL AGPVASALRE
     KLATVNWARA GLGLPLIDEL VSPEPEPLNT SEFSDWSSFN ASGSPEQEET ASASAAPAFY
     SQVPRPPASP SRPEQHTVIH MGNPEPLTHA SAPRKVYDTR DDERAPGLHR DCDDDKYRRR
     PALGWLAQLL RSRAGSRKRP LTLLQRAGLL LLLGLLGFLA LLALMSRLGR AAADSDPNLD
     PLMNPHIRVG PS