ID   ZFPL1_DANRE             Reviewed;         317 AA.
AC   P62447;
DT   05-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Zinc finger protein-like 1;
GN   Name=zfpl1; ORFNames=zgc:63760;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=AB;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for cis-Golgi integrity and efficient ER to Golgi
CC       transport. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, cis-Golgi network membrane
CC       {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ZFPL1 family. {ECO:0000305}.
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DR   EMBL; BC058063; AAH58063.1; -; mRNA.
DR   RefSeq; NP_956967.1; NM_200673.1.
DR   AlphaFoldDB; P62447; -.
DR   STRING; 7955.ENSDARP00000037977; -.
DR   PaxDb; P62447; -.
DR   GeneID; 393646; -.
DR   KEGG; dre:393646; -.
DR   CTD; 7542; -.
DR   ZFIN; ZDB-GENE-040426-1255; zfpl1.
DR   eggNOG; KOG3970; Eukaryota.
DR   InParanoid; P62447; -.
DR   OrthoDB; 807302at2759; -.
DR   PhylomeDB; P62447; -.
DR   PRO; PR:P62447; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR039043; ZFPL1.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR12981; PTHR12981; 1.
DR   Pfam; PF13639; zf-RING_2; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   2: Evidence at transcript level;
KW   ER-Golgi transport; Golgi apparatus; Membrane; Metal-binding;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport; Zinc;
KW   Zinc-finger.
FT   CHAIN           1..317
FT                   /note="Zinc finger protein-like 1"
FT                   /id="PRO_0000056320"
FT   TOPO_DOM        1..271
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        272..292
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        293..317
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   ZN_FING         1..43
FT                   /note="B box-type; degenerate"
FT   ZN_FING         53..101
FT                   /note="RING-type; degenerate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
SQ   SEQUENCE   317 AA;  35704 MW;  B94A3849E2F7C869 CRC64;
     MGLCKCPKKK VTNLFCFKHR VNVCEHCLVS NHNKCIVQSY LQWLQDSDYN PNCSLCIQPL
     DSQDTVRLVC YDLFHWSCLN ELASHQPLNT APDGYQCPTC QGPVFPPRNL ASPVADMLRE
     QLSSVNWARA GLGLPLIEDP EEEETTTHSG TSFSEWSTFE TTSVDVSMSN PTLTSLPPHQ
     DGEHIYNNRE QSAPNNTVFN MVTTSATDTV TISTVTSPRK LYDTRDLGHS AVMQIDFDDD
     KYRRRPALNW FAQVLKNCTS TKKKTLALKH RIFLLLLFGV IGFFTLIIIM AKFGRASAET
     DPNLDPLLNP NIRIGNM