ZFPL1_DROPS
ID ZFPL1_DROPS Reviewed; 302 AA.
AC Q298N4;
DT 25-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT 04-APR-2006, sequence version 1.
DT 03-AUG-2022, entry version 72.
DE RecName: Full=Zinc finger protein-like 1 homolog;
GN ORFNames=GA18838;
OS Drosophila pseudoobscura pseudoobscura (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=46245;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MV2-25 / Tucson 14011-0121.94;
RX PubMed=15632085; DOI=10.1101/gr.3059305;
RA Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S.,
RA Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., Couronne O.,
RA Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., van Batenburg M.F.,
RA Howells S.L., Scherer S.E., Sodergren E., Matthews B.B., Crosby M.A.,
RA Schroeder A.J., Ortiz-Barrientos D., Rives C.M., Metzker M.L., Muzny D.M.,
RA Scott G., Steffen D., Wheeler D.A., Worley K.C., Havlak P., Durbin K.J.,
RA Egan A., Gill R., Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y.,
RA Waldron L., Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F.,
RA Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M.,
RA Weinstock G.M., Gibbs R.A.;
RT "Comparative genome sequencing of Drosophila pseudoobscura: chromosomal,
RT gene, and cis-element evolution.";
RL Genome Res. 15:1-18(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ZFPL1 family. {ECO:0000305}.
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DR EMBL; CM000070; EAL27921.1; -; Genomic_DNA.
DR RefSeq; XP_001358778.1; XM_001358741.4.
DR AlphaFoldDB; Q298N4; -.
DR STRING; 7237.FBpp0282022; -.
DR EnsemblMetazoa; FBtr0283584; FBpp0282022; FBgn0078838.
DR GeneID; 4801735; -.
DR KEGG; dpo:Dpse_GA18838; -.
DR eggNOG; KOG3970; Eukaryota.
DR HOGENOM; CLU_075387_0_0_1; -.
DR InParanoid; Q298N4; -.
DR OMA; PSGHQCP; -.
DR PhylomeDB; Q298N4; -.
DR Proteomes; UP000001819; Chromosome 2.
DR Bgee; FBgn0078838; Expressed in female reproductive system and 2 other tissues.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0033227; P:dsRNA transport; IEA:EnsemblMetazoa.
DR Gene3D; 3.30.40.10; -; 1.
DR InterPro; IPR039043; ZFPL1.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12981; PTHR12981; 1.
DR SMART; SM00184; RING; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Membrane; Metal-binding; Phosphoprotein; Reference proteome; Transmembrane;
KW Transmembrane helix; Zinc; Zinc-finger.
FT CHAIN 1..302
FT /note="Zinc finger protein-like 1 homolog"
FT /id="PRO_0000355180"
FT TRANSMEM 258..278
FT /note="Helical"
FT /evidence="ECO:0000255"
FT ZN_FING 1..43
FT /note="B box-type; degenerate"
FT ZN_FING 53..101
FT /note="RING-type; atypical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
FT REGION 168..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 217
FT /note="Phosphoserine"
FT /evidence="ECO:0000250"
SQ SEQUENCE 302 AA; 33772 MW; 82659B7EA5FC1377 CRC64;
MGLCKCPKRL VTNQFCFEHR VNVCEHCMVQ SHPKCIVQSY LQWLRDSDYI SNCNLCGTSL
EQGECVRLVC YHVFHWDCLN ARQAALPANT APRGHQCPGC SVEIFPNTNL VSPVADALKN
YLAQVNWGRN GLGLALLSED QSSSLKAIKS KASVSQAAVS NMTKVHHIHS GGERERGKPN
GGDASTPHSV LLMDAFNPPS SGDFNASSRR PLLPRQSPIG GTDRDDNKYQ RRTPAALLSR
WTRRFYSPSS RPPWRRTWFL VLSGILAFVM FIYLLAWMGR SGSNDGLDES WNNPNPQPNH
YE
