ID   ZFPL1_XENLA             Reviewed;         320 AA.
AC   A1L2S8;
DT   25-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 55.
DE   RecName: Full=Zinc finger protein-like 1;
GN   Name=zfpl1;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Tail;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for cis-Golgi integrity and efficient ER to Golgi
CC       transport. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, cis-Golgi network membrane
CC       {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ZFPL1 family. {ECO:0000305}.
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DR   EMBL; BC129691; AAI29692.1; -; mRNA.
DR   RefSeq; NP_001091178.1; NM_001097709.1.
DR   RefSeq; XP_018111796.1; XM_018256307.1.
DR   AlphaFoldDB; A1L2S8; -.
DR   MaxQB; A1L2S8; -.
DR   DNASU; 100036939; -.
DR   GeneID; 100036939; -.
DR   KEGG; xla:100036939; -.
DR   CTD; 100036939; -.
DR   Xenbase; XB-GENE-991969; zfpl1.L.
DR   OMA; PSGHQCP; -.
DR   OrthoDB; 807302at2759; -.
DR   Proteomes; UP000186698; Chromosome 4L.
DR   Bgee; 100036939; Expressed in testis and 19 other tissues.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR039043; ZFPL1.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR12981; PTHR12981; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   2: Evidence at transcript level;
KW   ER-Golgi transport; Golgi apparatus; Membrane; Metal-binding;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport; Zinc;
KW   Zinc-finger.
FT   CHAIN           1..320
FT                   /note="Zinc finger protein-like 1"
FT                   /id="PRO_0000355173"
FT   TOPO_DOM        1..274
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        275..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        296..320
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   ZN_FING         1..43
FT                   /note="B box-type; degenerate"
FT   ZN_FING         53..101
FT                   /note="RING-type; degenerate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
SQ   SEQUENCE   320 AA;  35568 MW;  65BD45B1E4E75463 CRC64;
     MGLCKCPKRK VTNLFCFEHR VNVCEHCLVA NHAKCIVQSY LQWLQDSDYN PNCRLCNTLL
     SSKETARLVC YDLFHWSCLN DLATQQPPNT APAGYRCPSC QGPVFPPNNL VSPVAATLRE
     KLSTVNWARA GLGLPLIEVA EPVDDTMSHD ETDYRDWSVV NSSSDNLSET PETTSQTGYT
     YNSVAPGAVQ QSLNGNMSQD HAVTIRDTGS ESVPFNAASS PRKVYDTREN ARGQDAVIDF
     DDDKYRRRPT LNWLARILRN RSGSKSRPAS SMQRFLVILI IGVLGFLTLI LLMSKLGRAS
     ADNDPNLDPL LNPHIHVGKE