ID   ZFPL1_XENTR             Reviewed;         320 AA.
AC   Q0VFM0;
DT   25-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Zinc finger protein-like 1;
GN   Name=zfpl1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for cis-Golgi integrity and efficient ER to Golgi
CC       transport. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, cis-Golgi network membrane
CC       {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ZFPL1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC118779; AAI18780.1; -; mRNA.
DR   RefSeq; NP_001072211.1; NM_001078743.1.
DR   RefSeq; XP_012816743.1; XM_012961289.2.
DR   AlphaFoldDB; Q0VFM0; -.
DR   STRING; 8364.ENSXETP00000018044; -.
DR   PaxDb; Q0VFM0; -.
DR   DNASU; 779657; -.
DR   GeneID; 779657; -.
DR   KEGG; xtr:779657; -.
DR   CTD; 7542; -.
DR   Xenbase; XB-GENE-991966; zfpl1.
DR   eggNOG; KOG3970; Eukaryota.
DR   HOGENOM; CLU_075387_0_0_1; -.
DR   InParanoid; Q0VFM0; -.
DR   OMA; PNCALCN; -.
DR   OrthoDB; 807302at2759; -.
DR   PhylomeDB; Q0VFM0; -.
DR   TreeFam; TF315090; -.
DR   Proteomes; UP000008143; Chromosome 4.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000023095; Expressed in testis and 13 other tissues.
DR   ExpressionAtlas; Q0VFM0; baseline.
DR   GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
DR   InterPro; IPR039043; ZFPL1.
DR   InterPro; IPR001841; Znf_RING.
DR   PANTHER; PTHR12981; PTHR12981; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   2: Evidence at transcript level;
KW   ER-Golgi transport; Golgi apparatus; Membrane; Metal-binding;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport; Zinc;
KW   Zinc-finger.
FT   CHAIN           1..320
FT                   /note="Zinc finger protein-like 1"
FT                   /id="PRO_0000355174"
FT   TOPO_DOM        1..274
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        275..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        296..320
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000255"
FT   ZN_FING         1..43
FT                   /note="B box-type; degenerate"
FT   ZN_FING         53..101
FT                   /note="RING-type; degenerate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
FT   REGION          161..180
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   320 AA;  35523 MW;  8C42E1716540FCEA CRC64;
     MGLCKCPKRK VTNLFCFEHR VNVCEHCLVA NHAKCIVQSY LQWLQDSDYN PNCRLCNTLL
     SSKETARLVC YDLFHWSCLN DLATQLPPNT APAGYRCPSC QGPVFPPSNL VSPVAATLRE
     KLSTVNWARA GLGLPLIEVA EPVDDTMSHD ETDYRDWSVV NSSSDNLSET PETTSQTGYA
     YNSVPTSVAQ HSLNVNMSQD HAVTIRDTGS DSLTINAGSS PRKVYDTRET ARGQDAVIDF
     DDDKYRRRPT LSWLARILRN RSGSKSRPAS SMQRFLVILI IGVLGFLTLI LLMSKLGRAS
     ADNDPNLDPL LNPHIHVGKE